Responsibilities:
- Work closely with the team of Scientists/Associate Scientists in the Development team to define projects and drive results
- Be responsible for cross functional leadership of projects with high complexity, requiring detailed planning and execution
- Translate product needs into technical requirements to define project scope, team and timeline
- Lead technical troubleshooting
- Liaison with cross functional stakeholders to come to decisions and provide solutions for team execution as needed
- Perform deep and detailed technical review of data to identify trends and issues that need further investigation and testing
- Propose new ideas to improve methodologies in the lab, being either new/continuous development, application of new technologies, modification of quality control methods
- Define plans to validate assay performance aligned with CLSI guidelines
- Become an expert in our current assay performance, with deep understanding of quality metrics and analytical performance to inform improvements and continued development
- Develop test protocols, reports and any other technical documents that are clear, direct and complete
- Work closely with Quality, Regulatory and technical writers to perfect technical documentation; iterate new versions to incorporate cross functional feedback
- Understand and address needs from the Regulatory and Quality teams for successful regulatory filings
- Provide formal management of team members, as needed
- Support on new team member hiring and onboarding, as needed
- Assist with training of new laboratory personnel and training of new procedures with existing personnel
- These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.
Required Qualifications:
- Ph.D. or equivalent in Molecular Biology or other relevant field
- At least 8 years of related experience in a laboratory with high-complexity molecular assays
- Expertise in understanding and handling high dimensional datasets generated from sequencing technologies
- Former experience working with automated platforms is required
- Proficient in data analysis using R, JMP or other coding languages
- Proficient in Google Suite and Microsoft office (text editor, spreadsheets and slides)
Preferred Qualifications:
- Former experience with methylation and cfDNA assays is a plus
- Experience with the development and implementation of clinical laboratory tests under CAP/CLIA or IVD/FDA/regulated environments is a plus
Physical Demands and Work Environment
- Hours and days may vary depending on operational needs.
- Working with dry ice may be necessary.
- Standing or sitting for long periods of time may be necessary.
- May be exposed to hazardous materials, blood specimens and instruments with moving parts, heating or freezing elements, and high speed centrifugation.
- Repetitive manual pipetting may be necessary.
- Some lifting (up to 25 pounds) may be necessary
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What We Do
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is using the power of high-intensity sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop and commercialize pioneering products.
Why Work With Us
Everything we do is guided by our mission to detect cancer early, when it can be cured. It’s the reason we’re here, and it’s no small task. The right people make all the difference. That’s why we’re looking for those who strive to share their knowledge, contribute their skills, inspire each other and commit to something bigger than themselves.
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GRAIL Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
GRAIL has a variety of work types depending on the roles. Some are onsite like a lab role, others are hybrid and still others are remote. Hybrid is typically Tuesday and Thursday but leaders may be flexible depending on the role.








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