We are seeking a Senior Systems Engineer to join our team in Portland, OR (PDX). In this role, you will lead the development, validation, and integration of cutting-edge automated laboratory instrumentation and bioprocess technologies. Working at the intersection of hardware, software, and biology, you will design automated workflows, write custom integration scripts, and connect robotic systems with enterprise LIMS infrastructure to drive operational excellence and product quality under ISO 13485 standards.
What You’ll Do- Develop, validate, and release new processes and technologies to achieve cost-effectiveness and improved product quality
- Develop and test protocols, scripts, and systems to automate certain bioprocesses
- Operation and maintenance of a range of scientific instruments and tools with a focus on laboratory automation systems and cross-integration systems
- Collaborate with multi-disciplinary teams in troubleshooting and resolving issues concerning equipment and systems
- Prepare and participate in documentation, knowledge transfer, and training activities
- Follow regulatory and ISO 13485 requirements
- Ph.D. or MS with 3 years, BS with 5 years of related experience in Biomedical Engineering, Chemical Engineering, Mechanical/Electrical Engineering, or related field
- Experience in developing automated instrumentation for bioprocesses
- Experience with DoE for testing and troubleshooting of certain processes
- Experience in designing and writing scripts (C#, Python, etc) using control software or dynamic scheduling software native to laboratory automation systems and cross-integration systems
- Experience with sample tracking software and developed interfaces between robotic instrumentation and LIMS systems (MES/Maestro, Twist build)
- Excellent scientific computation and data analysis capabilities
- Hands-on skills to assemble and maintain hardware
- Experience with biological instrumentation for liquid transfer, PCR, cell-based cloning, DNA extraction, and purification is desirable
- Working collaboratively with other functional groups
- Excellent communication and writing skills, and ability to work in a fast-paced team environment
About Twist Bioscience
Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.
At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.
Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.
Skills Required
- Ph.D. or M.S. in Biomedical Engineering, Chemical Engineering, Mechanical Engineering, Electrical Engineering, or a related field, plus 3 years of related experience
- B.S. in Biomedical Engineering, Chemical Engineering, Mechanical Engineering, Electrical Engineering, or a related field, plus 5 years of related experience
- Experience developing automated instrumentation for bioprocesses
- Experience using Design of Experiments for process testing and troubleshooting
- Experience designing and writing scripts in C#, Python, or similar languages for laboratory automation control or scheduling software
- Experience with sample-tracking software and interfaces between robotic instrumentation and LIMS systems, including MES/Maestro or Twist Build
- Strong scientific computation and data analysis capabilities
- Hands-on ability to assemble and maintain hardware
- Experience with liquid-transfer, PCR, cell-based cloning, DNA extraction, and purification instrumentation
- Ability to collaborate with other functional groups
- Excellent communication and technical writing skills
- Ability to work effectively in a fast-paced team environment
What We Do
Twist Bioscience is a synthetic biology company based in South San Francisco, California. The company has developed a proprietary silicon-based manufacturing process for the production of synthetic DNA. Twist Bioscience serves Life Science researchers who are changing the world for the better. Coming from diverse fields of medicine, agriculture, industrial chemicals and data storage, scientists use our synthetic genes, oligo pools, and NGS target enrichment to better lives and improve the sustainability of the planet. Twist Bioscience is uniquely positioned to help accelerate these efforts by providing precision at a scale that is otherwise unavailable. Our technology overcomes inefficiencies and enables cost-effective, rapid, precise, high-throughput DNA synthesis and sequencing. We offer both the quality and quantity researchers need now to rapidly realize opportunities ahead.
