About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job DescriptionThe Quantitative, Translational ADME Sciences (QTAS) department at AbbVie is seeking a highly motivated scientist to join the Biologics bioanalysis, characterization, and proteomics group. The main function of this position is to develop and implement LC/MS (liquid chromatography/mass spectrometry)-based bioanalysis and in vitro characterization assays of novel biologics entities. The successful candidate will be experienced in the optimization and implementation of novel and routine LC/MS-based bioanalytical methods to drive in vivo PK, TK, and PK/PD analysis as well as in vitro stability characterization of biotherapeutics. The candidate will be responsible for sample preparation, method development, bioanalytical assay operations, data analysis, report generation, and data presentation.
Key tasks and responsibilities:
- Operate and maintain LC/MS instruments to generate high-quality experimental data.
- Perform affinity purification of biotherapeutic (including but not limited to monoclonal and multispecific antibody, antibody drug conjugates, antibody-siRNA conjugates, and tLNPs).
- Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
- Facilitate assay optimization and implementation to ensure laboratory capacity and data quality.
- Communicate data interpretation internally and externally.
Qualifications
- Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
- Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as team player and individual contributor.
- Prior industry experience in drug discovery/development is preferred. In-depth understanding of in vivo PK, TK and PK/PD studies and corresponding bioanalytical assays as well as in vitro characterization assays is highly desired.
- In-depth understanding of protein mass spectrometry and hands-on experience with QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers are highly desired.
- Hands-on experience with automated liquid handling systems is highly desired.
- Demonstrated ability to manage and analyze data using advanced software tools such as Protein Metrics Byos and GraphPad Prism.
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Skills Required
- Bachelor's Degree (10 years' experience) or Master's Degree (8 years' experience) or PhD (no experience required)
- Develop and implement LC/MS-based bioanalysis and in vitro characterization assays
- Operate and maintain LC/MS instruments and generate high-quality experimental data
- Perform affinity purification of biotherapeutics (mAbs, multispecifics, ADCs, antibody-siRNA conjugates, tLNPs)
- In-depth understanding of protein mass spectrometry
- Hands-on experience with QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX), and/or Orbitrap (Thermo) mass spectrometers
- Hands-on experience with automated liquid handling systems
- Demonstrated ability to manage and analyze data using Protein Metrics Byos and GraphPad Prism
- Maintain detailed, accurate study documentation in electronic laboratory notebooks
- Prior industry experience in drug discovery/development (preferred)
- In-depth understanding of in vivo PK, TK, and PK/PD studies and corresponding bioanalytical assays
AbbVie Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AbbVie and has not been reviewed or approved by AbbVie.
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Retirement Support — 401(k) contributions include a dollar-for-dollar match up to 6% plus an additional annual company contribution tied to age and service. Company-paid life insurance and other financial protections further strengthen long-term security.
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Parental & Family Support — Paid leave programs include up to 12 weeks at 100% for parental leave and separate paid caregiver leave, with eligibility after six months where noted. Adoption and surrogacy reimbursements and family-building resources add further support.
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Healthcare Strength — Health coverage begins on day one with medical, dental, vision, mental health, and prescription benefits, and preventive care covered at 100%. Options such as HSAs/FSAs and coverage for spouses/domestic partners and children up to age 26 broaden accessibility.
AbbVie Insights
What We Do
AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.
