About This Role:
As a Sr. Scientist in Biomarker Discovery, you will play a pivotal role in advancing immunology therapeutics within our organization. Working with the WCH team, you will lead and execute cutting-edge biomarker research across non-clinical and clinical stages. Your expertise will be crucial in generating high-quality biomarker data from non-human primate and human samples, focusing on mechanism of action, target engagement, and immune pathway modulation. This position requires a strong hands-on approach to experimental work, particularly in flow cytometry-based assays, while collaborating closely with clinical and translational partners. Your contributions will be essential in bridging immune biology with clinical development, providing decision-enabling insights that drive clinical strategies and therapeutic advancements.
What You’ll Do:
Lead and execute clinical and translational biomarker research to establish mechanism of action, target engagement, and immune pathway modulation for clinical-stage immunology therapeutics.
Independently design, perform, analyze, and interpret experiments using primary human samples to generate robust, decision-enabling biomarker data.
Develop, optimize, and own multiparameter flow cytometry–based clinical biomarker assays, including immune phenotyping, receptor occupancy, and pharmacodynamic readouts.
Support assay qualification, method transfer to CROs, and longitudinal clinical biomarker data review, ensuring assay robustness and interpretability.
Communicate biomarker insights clearly to cross-functional stakeholders to influence clinical strategy, study interpretation, development decision, and scientific narrative.
Who You Are:
You are an innovative thinker with a passion for immunology and biomarker research. Your meticulous attention to detail and analytical mindset enables you to design and interpret complex experiments. You thrive in collaborative environments, where your ability to communicate complex scientific concepts clearly to various stakeholders makes you an invaluable team member. Your dedication to advancing clinical-stage therapeutics is driven by a desire to impact patient care positively.
Required Skills:
PhD in Immunology or related biomedical science field (Bachelors or Masters with additional directly relevant experience may be considered).
2+ years of relevant industry or translational research experience supporting clinical-stage immunology programs (6+ years with MS, 8+ years with BS).
Expertise in flow cytometry based assays and biomarker development.
Strong analytical and experimental skills in immunology research.
Excellent communication skills to convey scientific insights effectively.
Preferred Skills:
Experience in assay qualification and method transfer to CROs.
Proficiency in immune phenotyping, receptor occupancy, and pharmacodynamic readouts.
Familiarity with clinical biomarker data review and interpretation.
Additional Information
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to:
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
Skills Required
- PhD in Immunology or related biomedical science field
- 2+ years of relevant industry or translational research experience
- Expertise in flow cytometry based assays and biomarker development
- Strong analytical and experimental skills in immunology research
- Excellent communication skills to convey scientific insights effectively
Biogen Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Biogen and has not been reviewed or approved by Biogen.
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Fair & Transparent Compensation — Pay is generally positioned as competitive and often perceived as fair across roles, with total compensation framed as strong when bonus and equity are included. Compensation sentiment is described as above-average overall, though it varies by function and business cycle.
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Equity Value & Accessibility — Equity programs are repeatedly highlighted as a meaningful part of the total package, including stock programs and an employee stock purchase plan. Equity and bonus elements are portrayed as important contributors to feeling well rewarded beyond base pay.
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Leave & Time Off Breadth — Time-off benefits are described as distinctive, including a year-end shutdown and a paid sabbatical after extended tenure. Vacation, holidays, sick time, and personal-significance days are also presented as supportive of work-life needs.
Biogen Insights
What We Do
Through cutting-edge science and medicine, Biogen discovers, develops and delivers innovative therapies worldwide for people living with serious neurological and neurodegenerative diseases. Founded in 1978, Biogen is a pioneer in biotechnology and today the Company has the leading portfolio of medicines to treat multiple sclerosis, has introduced the first and only approved treatment for spinal muscular atrophy, and is at the forefront of neurology research for conditions including Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis. Biogen also manufactures and commercializes biosimilars of advanced biologics. With approximately 7000 people worldwide, we are truly a global organization, headquartered in Cambridge, Massachusetts, which is also home to our research operations. Our international headquarters are based in Zug, Switzerland and we have world-class manufacturing facilities in North Carolina and Denmark. We offer therapies globally through direct affiliate presence in 30 countries and a network of distribution partners in over 50 additional countries. For more information, please visit www.biogen.com. Follow us on social media – Twitter, LinkedIn, Facebook, YouTube.
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