As a Senior Plant Engineer in Facilities and Engineering, you will own the technical systems and ensure the efficient, safe, and reliable operation of critical mechanical, electrical, and process / utilities infrastructure at the Dixon and South San Francisco (SSF) sites. This high-impact, strategic role directly mitigates severe business interruption risks to critical research and manufacturing facilities, influencing multi-million-dollar investments and operational costs. You will consult on construction, represent the organization on infrastructure initiatives, collaborate with IFM providers, and develop maintenance/operation strategies and procedures. You will work autonomously as a subject matter expert, supporting gRED Research Customers and Facilities leadership. This role combines hands-on technical system ownership with strategic data analysis to enable our mission.
The Opportunity
Responsibilities:
Technical System Ownership
Provide technical expertise and operational support for mechanical, electrical, and process / utilities infrastructure, maximizing system uptime and ensuring equipment reliability.
Maintain engineering documentation, risk/criticality assessments, maintenance strategies, and critical spares, overseeing the full asset lifecycle.
Ensure reliable facility operations while applying proficient knowledge of technical standards, drawings, schematics, and codes (ASHRAE, OSHA, NFPA).
Support audits for regulatory/internal compliance.
Define critical spare parts, BoMs, maintenance strategies, and ensure accurate asset data in CMMS.
Own the sequence of operations and functional requirements for equipment controlled, monitored and alarmed by the Building Automation System (BAS).
Leverage Building Automation data and history for trending, troubleshooting, and continuous improvement.
Develop complex PM and LOTO job plans.
Asset Reliability Responsibilities and Expertise
Act as system owner for critical mechanical, electrical, and process infrastructure throughout the asset lifecycle.
Execute risk/criticality and condition assessments.
Ensure reliability/maintainability from design through hand-over to operations for capital projects.
Champion Reliability-Centered Maintenance (RCM) to maximize system uptime, Reliability, Maintainability, and Availability (RMA).
Lead structured Root Cause Analysis (RCA) and Root Cause Failure Analysis (RCFA) for equipment failures and emerging issues.
Analyze data from CMMS, BAS, and Historians for RCAs and continuous improvement.
Areas of Expertise
Comprehensive knowledge of critical facilities infrastructure including HVAC (cooling towers, chillers, refrigerated water, heating hot water) industrial/domestic water, purified water, compressed air and steam generation systems.
Ownership of electrical infrastructure including emergency backup power, UPS, lighting, and building electrical distribution.
Leveraging BAS knowledge and experience for troubleshooting and making corrective adjustments as needed to maintain critical environmental conditions.
Reliability Engineering proficiency in root cause and failure analysis methods (FMEA, RCFA) and statistical process control.
Drive sustainability, energy efficiency, and operational improvements to reduce costs and risks.
Who You Are
Required Qualifications
BA/BS in Mechanical, Chemical, Industrial engineering or equivalent technical field.
Minimum 8 years of relevant mechanical, electrical, and process / utilities infrastructure design/operation experience in high-tech, industrial, life sciences, or chemical manufacturing.
Minimum 3 years of experience in a large, multi-functional campus environment.
Proficient knowledge of BAS and CMMS (e.g., SAP, Siemens).
Working knowledge of industry standards (ANSI/ASHRAE, NEMA, NFPA, EPA, OSHA) and documentation (P&IDs, process flow diagrams).
Proven experience investigating, troubleshooting, and correcting mechanical, electrical, and process / utilities infrastructure equipment/systems.
Experience in plant engineering across R&D, manufacturing, and commercial operations.
Demonstrated experience optimizing equipment operation for efficiency and reliability.
Excellent interpersonal effectiveness and communication skills (written/oral).
Proficient understanding of safety principles and quality systems in regulated environments.
This position is not eligible for relocation.
The expected salary range for this position based on the primary location of California is $109,500 - $203,300 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Skills Required
- Bachelor of Science in Mechanical, Chemical, Industrial or equivalent field of Engineering
- 8 or more years of relevant experience in design and operation of facilities, equipment, and utilities
- Experience with optimization of equipment operation
- Understanding of interface with automation and controls
- Requires overall working knowledge of Reliability Centered Maintenance
- Proficient in facilitating failure analysis methods
- Formal training in statistics and/or statistical process control
- Experienced in gathering and analyzing large amounts of data
- Proficiency with SAP CMMS
Genentech Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Genentech and has not been reviewed or approved by Genentech.
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Healthcare Strength — Health coverage is described as comprehensive across medical, dental, vision, mental health, and prescriptions, supported by HSAs/FSAs and broad wellness resources. On‑site fitness and health centers, mental‑health clinicians, and specialized programs like fully covered preventive cancer screenings and menopause support deepen the offering.
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Retirement Support — Retirement benefits feature a 401(k) with up to a 4% company match plus an additional annual 6% company contribution to eligible pay. Additional financial protections such as life and accident insurance complement salary, bonuses, and stock options.
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Leave & Time Off Breadth — Time away includes about 20 paid vacation days, paid holidays, personal days, and a year‑end shutdown. A paid six‑week sabbatical every six years notably expands long‑term time‑off flexibility.
Genentech Insights
What We Do
Considered the founder of the industry, Genentech, now a member of the Roche Group, has been delivering on the promise of biotechnology for more than 40 years. Genentech is a biotechnology company dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions. That is why we use cutting-edge science to create and deliver innovative medicines around the globe. To us, science is personal. Making a difference in the lives of millions starts when you make a change in yours.
