Software Engineer II

Posted Yesterday
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Chicago, IL, USA
Hybrid
85K-130K Annually
Mid level
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Analytics • Biotech • Generative AI
Tempus is a technology company leading the adoption of AI to advance precision medicine and patient care.
The Role
Design, implement, and deliver full‑stack features for Genomics AI initiatives. Integrate generative AI tools and agents, build scalable microservices and APIs, optimize relational queries and caching, mentor junior engineers, and collaborate cross‑functionally to resolve technical dependencies and shape architecture decisions.
Summary Generated by Built In

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

About our Teams:

At Tempus, products are owned and developed by small, autonomous teams composed of developers, designers, scientists, and product managers. You and your team set the goals, build the software, deploy the code, and contribute to a growing software platform that will make a lasting impact in the field of cancer research and treatment.

About the Role: 

We are seeking a highly motivated and capable Software Engineer to further our Genomics AI initiatives. This person should have experience and interest in leading analysis and design of technical problems, mentoring & coaching emerging talent during this transformative time in Tech. This position requires experience with programming (full stack), relational data systems and algorithms development. Top candidates will also have experience crafting code while leveraging AI tooling and embedding agentic workflows in their product.

Why We’re Looking for You

  • You bring solid experience on software development teams, stepping beyond feature execution into leading technical analysis, design, and tradeoffs.

  • You excel at solving complex problems through data-driven, iterative software development in distributed, event-based architectures.

  • You possess a strong command of modern backend and frontend technologies and are excited to leverage AI-assisted development tools to move faster and build smarter.

  • You thrive in fast-paced, agile environments—helping coordinate cross-team collaboration, troubleshooting technical roadblocks, and documenting architecture.

  • You take pride in mentoring other engineers, elevating engineering standards, and continuously learning alongside a collaborative team.

Responsibilities

  • Own end-to-end design, implementation, and delivery of core features in service of team and quarterly goals.

  • Integrate Generative AI tools and autonomous coding agents (e.g., GitHub Copilot, Cursor, Claude Code) into your workflow to accelerate feature development, streamline test generation, and rapidly prototype solutions.

  • Write clean, resilient code using enterprise design patterns that are flexible, performant, and adaptable to evolving business requirements.

  • Contribute to microservice and database architecture decisions, keeping scalability, caching strategies, and distributed performance top of mind.

  • Proactively identify technical dependencies, surface roadblocks early, and coordinate with product managers and other engineering teams.

  • Support junior team members through constructive code reviews, pair programming, and actionable coaching.

Technical Requirements

  • 3+ years of professional software development experience in an agile development environment.

  • Strong proficiency in TypeScript/JavaScript, Node.js, and modern frontend frameworks like React.

  • Hands-on experience using GenAI coding tools and agents (e.g., Copilot, Cursor, LLM APIs) to assist in writing code, refactoring, writing unit/integration tests, and accelerating feature delivery.

  • Solid experience working with relational databases (PostgreSQL or MySQL) and query optimization, as well as caching solutions (Redis).

  • Proven track record designing RESTful/GraphQL APIs and building within distributed or microservice architectures.

  • Hands-on experience with cloud platforms (GCP or AWS) and CI/CD development pipelines.

Bonus Points

  • Experience building features that incorporate GenAI/LLM APIs into user-facing applications.

  • Experience with Elasticsearch/Opensearch

  • Experience with containerization and orchestration (Docker, Kubernetes).

  • Background in biotech, genomics, or precision medicine.

CHI: $85,000-$130,000


The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. 

Skills Required

  • 3+ years of professional software development experience in an agile development environment.
  • Proficiency in TypeScript and JavaScript.
  • Experience with Node.js.
  • Experience with modern frontend frameworks such as React.
  • Full-stack development experience.
  • Experience with algorithms development.
  • Hands-on experience using GenAI coding tools and agents (e.g., GitHub Copilot, Cursor, LLM APIs).
  • Experience with relational databases (PostgreSQL or MySQL) and query optimization.
  • Experience with caching solutions (Redis).
  • Proven track record designing RESTful and/or GraphQL APIs.
  • Experience building within distributed or microservice architectures.
  • Hands-on experience with cloud platforms (GCP or AWS) and CI/CD pipelines.
  • Mentoring and coaching junior engineers.
  • Experience building features that incorporate GenAI/LLM APIs into user-facing applications.
  • Experience with Elasticsearch or OpenSearch.
  • Experience with Docker and Kubernetes.
  • Background in biotech, genomics, or precision medicine.

What the Team is Saying

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Tempus AI Compensation & Benefits Highlights

  • Healthcare Strength Medical, dental, and vision insurance are standard and employer‑verified, complemented by life/disability coverage, HSA/FSA, mental health resources, and EAP. Company materials and verified listings indicate these core benefits are well established as of mid‑2026.
  • Leave & Time Off Breadth Vacation/Paid Time Off, Sick Leave, and Paid Holidays are explicitly offered on employer‑verified pages. Many roles are described as having flexible or unlimited PTO, though laboratory staff may follow separate policies.
  • Wellbeing & Lifestyle Benefits On‑site conveniences such as a cafeteria, stocked kitchens, and an on‑site barista are highlighted for select offices, alongside wellness initiatives, gym discounts, commuter benefits, and charitable matching. These day‑to‑day perks are emphasized on official culture/benefits pages and aligned third‑party summaries.

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The Company
HQ: Chicago, IL
3,775 Employees
Year Founded: 2015

What We Do

We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time, connect patients with therapies and clinical trials, and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data, Tempus partners with more than half of U.S. oncologists and the majority of the top 20 global pharma companies. Our teams are pioneering work across oncology, neurology, psychiatry, cardiology, and beyond—transforming how care is delivered and therapies are developed. At Tempus, every role contributes to our mission: to help each patient benefit from the experiences of those who came before. For more information, visit tempus.com.

Why Work With Us

We’re looking for people who can change the world. People who question the status quo and refuse to shy away from tough problems. For builders who are never done building, and the learners who are never done learning. Passionate individuals with undying curiosity who want to take on one of the greatest challenges humanity has ever faced—head on.

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Tempus AI Offices

Hybrid Workspace

Employees engage in a combination of remote and on-site work.

Most of the team follows a hybrid policy, with some roles allowing for a fully remote arrangement and some roles being onsite only.

Typical time on-site: 3 days a week
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