Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
The EHS Senior Specialist reports to the Site Environmental, Health & Safety (EHS) Manager and supports the planning, implementation, and continuous improvement of EHS programs for the Madison facility. This role helps develop and maintain a comprehensive occupational health and safety program, including safety inspections, incident investigations, laboratory-focused EHS training, and environmental compliance activities.
The EHS Senior Specialist will help ensure compliance with applicable federal, state, and local environmental, health, and safety regulations while promoting a strong site safety culture.
Responsibilities
- Support the development and implementation of EHS systems, programs, and procedures designed to prevent occupational injuries and illnesses, reduce unsafe conditions and behaviors, and strengthen employee engagement in site safety.
- Participate in incident investigations to identify root causes and support the development and implementation of sustainable corrective and preventive actions.
- Conduct facility audits, surveys, and inspections to identify environmental, occupational health, and safety hazards; evaluate compliance with applicable regulations; and recommend practical corrective actions and process improvements.
- Maintain required EHS records and support timely regulatory reporting.
- Review and support risk assessments related to process hazards, new equipment and processes, chemicals, biological materials, and personal protective equipment (PPE).
- Support hazardous chemical and biological waste management activities, including proper handling, transportation, documentation, and disposal.
- Develop and deliver EHS training programs, with an emphasis on laboratory safety, chemical safety, biosafety, and injury prevention.
- Monitor contractor activities to ensure compliance with site safety policies and applicable requirements.
- Serve as the EHS representative on projects involving new equipment, process improvements, facility changes, and PPE assessments.
- Recommend and implement improvements that promote environmental, health, and safety excellence across the site.
- Perform other duties as assigned based on business needs.
- Comply with all applicable regulations, company policies, standard operating procedures, work instructions, and safety requirements.
Requirements
- Bachelor’s degree in Occupational Safety, Engineering, Environmental Science, or a related discipline.
- 5 years of experience in an EHS role, preferably within a research and development, laboratory, manufacturing, or biotechnology environment.
- Strong knowledge of biosafety and chemical safety practices in a research and development environment.
- Demonstrated ability to develop and deliver effective EHS training.
- Excellent written, verbal, and interpersonal communication skills.
- Strong organizational, analytical, and problem-solving skills, with a high level of initiative and sound judgment.
- Proficiency with standard business software, including Microsoft Office applications.
- Ability to lift and move materials weighing up to 50 pounds, with or without reasonable accommodation.
Preferred
- Experience working in a regulated pharmaceutical, biotechnology, laboratory, or manufacturing environment.
- Working knowledge of applicable EHS regulations and compliance requirements.
- Ability to work effectively both independently and collaboratively in a cross-functional environment.
- Commitment to maintaining compliance with company quality, safety, and standard operating procedures.
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
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Skills Required
- Bachelor’s degree in Occupational Safety, Engineering, Environmental Science, or a related discipline
- Five years of experience in an EHS role
- Strong knowledge of biosafety and chemical safety practices in a research and development environment
- Demonstrated ability to develop and deliver effective EHS training
- Excellent written, verbal, and interpersonal communication skills
- Strong organizational, analytical, and problem-solving skills
- High level of initiative and sound judgment
- Proficiency with standard business software, including Microsoft Office applications
- Ability to lift and move materials weighing up to 50 pounds, with or without reasonable accommodation
- Experience in a regulated pharmaceutical, biotechnology, laboratory, or manufacturing environment
- Working knowledge of applicable EHS regulations and compliance requirements
- Ability to work effectively independently and collaboratively in a cross-functional environment
- Commitment to compliance with company quality, safety, and standard operating procedures
What We Do
Arrowhead Pharmaceuticals is a clinical stage, Nasdaq listed (ticker ARWR) company developing medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, our therapies trigger the RNA interference mechanism to induce rapid, deep and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Our RNAi-based therapeutics are at the leading edge of genetic-based therapy with the potential to bring life changing treatments for patients. Our Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. The TRiM platform builds on more than a decade of work on actively targeted drug delivery and offers several advantages including simplified manufacturing and reduced costs; multiple routes of administration; and potential for improved safety. Our employees are nimble, science-driven, and innovative professionals. A career at Arrowhead offers the opportunity to collaborate with top notch scientists to rapidly discover and develop RNAi-based therapeutics to add to our growing pipeline. Research and development activities are located in Madison, WI. Our R&D group includes fully-integrated capabilities for chemistry, biology, and toxicology. Madison is an exciting and sophisticated city that includes state government, the flagship campus of the University of Wisconsin, and major research organizations. Our HQ, clinical and regulatory operations are located in Pasadena, CA. Just north of Los Angeles and resting in the foothills of the San Gabriel Mountains, Pasadena is known for its natural scenic beauty, vibrant cultural and academic environment and rich architectural setting.
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