Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis—provides a color-coded, 3D model of a patient’s coronary arteries indicating the impact blockages have on blood flow to the heart. Heartflow is the first AI-driven non-invasive integrated heart care solution across the CCTA pathway that helps clinicians identify stenoses in the coronary arteries (RoadMap™Analysis), assess coronary blood flow (FFRCT Analysis), and characterize and quantify coronary atherosclerosis (Plaque Analysis). Our pipeline of products is growing and so is our team; join us in helping to revolutionize precision heartcare.
Heartflow is a publicly traded company (HTFL) that has received international recognition for exceptional strides in healthcare innovation, is supported by medical societies around the world, cleared for use in the US, UK, Europe, Japan and Canada, and has been used for more than 500,000 patients worldwide.
We are looking for a Senior Software Engineer to join our world-class engineering team. In this role, you will help design and develop cloud-based services and modern web applications that power the next generation of Heartflow technologies, including a new orchestration pipeline, which will drive critical workflows across the company.
You will work cross-functionally with Software Engineers, Product Managers, Quality Assurance, Usability Designers, Process Engineers, and Regulatory to create impactful internal applications and infrastructure. This role offers the opportunity to contribute meaningfully to the design, scalability, and performance of our platforms, while ensuring regulatory compliance in a fast-paced, innovative environment.
Key Responsibilities- Lead end-to-end feature development across the full technology stack
- Independent, end-to-end ownership of the design, development, testing, and maintenance of robust APIs (Python, AWS), interactive web applications (Django backend and Vue.js frontend), pipeline orchestrations, and associated infrastructure.
- Contribute to the long-term technical roadmap by providing architectural feedback that ensures current systems remain compatible with future orchestration goals.
- Mentor junior engineers and contribute to the technical excellence of our team.
- Make data-driven decisions while practicing creative problem solving.
- Write clean, maintainable, well-documented code with a focus on high-stakes quality, performance, and user experience.
- Improve infrastructure components including orchestration pipelines, test frameworks, and CI/CD workflows.
- Lead the technical integration of emerging tools, such as Agentic AI frameworks, to automate internal developer workflows and improve team velocity.
- Contribute to releases of application deployments and participate in on-call production support as needed.
- Collaborate cross-functionally with Product, Design, and Engineering stakeholders to define and implement product features.
- Participate in code reviews and champion engineering best practices.
- Contribute to a culture of technical excellence, innovation, best practices, and continuous improvement.
- Ensure compliance with FDA regulations for medical software and supporting systems, including documentation and quality assurance processes.
- Education:
- BS in Computer Science or a related technical field + 5 years of experience;
- OR MS/PhD in Computer Science or related field + 3 years;
- OR equivalent practical experience as a full-stack software engineer.
- Proficiency in TypeScript or JavaScript.
- Strong development experience with Python.
- Strong cloud development experience (preferably AWS).
- Familiarity with modern web frameworks (Django & Vue.js strongly preferred, but Angular/React is acceptable).
- Deep understanding of backend and frontend security best practices.
- Strong problem-solving skills with the ability to analyze and resolve complex issues.
- Solid grasp of modern software development methodologies including CI/CD, testing, and Agile practices.
- Excellent communication and collaboration skills.
- Advanced proficiency in:
- Python, Django, JavaScript, TypeScript, Vue.js
- Nginx, Pytest, GitHub, GitHub Actions
- Hands-on experience designing and building orchestration pipelines.
- Strong AWS experience with services such as:
- Kubernetes, CDK, Step Functions, Lambdas, API Gateway, Fargate, ECS, Aurora (MySQL 8.0+)
- Demonstrated success in delivering cloud-native APIs, scalable web apps, and complex distributed systems.
- Experience developing regulated medical software (e.g., Software as a Medical Device) in compliance with FDA
Why Join Heartflow?
- Work on meaningful, life-changing products.
- Collaborate with top-tier engineers and innovators.
- Competitive compensation and benefits.
- Be part of a mission-driven company improving cardiovascular care globally.
If you're passionate about solving complex challenges, innovating in cloud technology, and creating impactful software that improves patient outcomes, we’d love to hear from you.
A reasonable estimate of the base salary compensation range is $180,000 to $215,000, bonus, and equity. #LI-IB1
Skills Required
- BS in Computer Science or related field or MS/PhD with 3 years of experience
- Proficiency in TypeScript or JavaScript
- Strong development experience with Python
- Strong cloud development experience with AWS
- Familiarity with Django and JavaScript frameworks
- Deep understanding of backend and frontend security best practices
- Strong problem-solving skills
- Solid grasp of modern software development methodologies including CI/CD and Agile practices
- Excellent communication and collaboration skills
What We Do
Heartflow is the global leader in AI-driven coronary artery disease (CAD) management, transforming how CAD — the world’s leading cause of death — is diagnosed and treated. Our advanced technology generates personalized, precision 3D heart models from a single CT scan, providing clinicians with the clarity and confidence to deliver earlier, more effective treatments — transforming CAD into a disease that can be managed for life. Heartflow One is the only complete, non-invasive, precision coronary care platform providing patient insights throughout the guideline-directed CCTA pathway. The AI-driven platform — including Roadmap™ Analysis, FFRCT Analysis and Plaque Analysis — is supported by the ACC/AHA Chest Pain Guideline and backed by more than 600 peer-reviewed publications. With over 400,000 patients treated, more than 1,400 leading institutions adopting our solution, and 99.5% of U.S. lives covered — Heartflow is redefining the standard of coronary care. We're a global company, with employees across the United States, Europe and Japan. Our headquarters are in Mountain View, California, with additional offices in California, Texas, the UK, and Japan. We believe CAD shouldn’t be a silent threat. By making it screenable, diagnosable, and manageable, we’re changing the story of CAD, empowering clinicians to save lives and giving patients more time for what matters most.
Why Work With Us
Join Us to Rewrite the Story of CAD.
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