Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
We are seeking a Senior Software Engineer to help design, build, and scale high-quality software systems at Tempus. This role is ideal for an experienced engineer who can work across the stack, contribute to architecture and design, improve engineering quality, and collaborate effectively across teams to deliver reliable products and services. Come help our team build the de-identification systems behind Tempus, which turn identified clinical, molecular, and other patient data into research-ready datasets. You'll design and scale the data pipelines and event-driven services that protect patient privacy while preserving the data's analytic utility for precision medicine research.
Why we’re looking for you:
- You've got a few years of experience working on software development teams, and can help lead in technical analysis & design, evaluating tradeoffs, and establishing best practices
- You love exploring hard problems and solving them with data-driven, iterative software development
- You understand the challenges and appreciate the rewards of a distributed and event-based architecture
- You've worked in fast-paced, agile environments and helped keep projects on track, troubleshoot roadblocks, write documentation, and coordinate cross-team collaboration
- You enjoy learning from and collaborating with a diverse, talented team and mentoring junior team members
Bonus points for:
- Experience with Docker, AWS, GCP
- Experience in Python, Spark, dbt, SQL, Airflow
- Experience in biotech, genomics, and precision medicine
Responsibilities:
- Own and deliver projects in service of quarterly goals of the team
- Navigate ambiguity and remain resilient through ups and downs
- Work collaboratively with leadership to set realistic ambitious goals, breaking those goals down to smaller projects for the team to execute on
- Support the growth of teammates by taking into account their skills, background and workstyles
- Give constructive feedback, coaching more than criticizing and avoiding blame to solve the right problems. Ultimately, disagreeing and committing when necessary.
- Write code that captures the essential nature of the solution and is appropriately flexible, reusable, efficient, and adaptable to changing requirements
- Proactively identify issues with technical dependencies of your project that are owned by other teams and surface them
What Success Looks Like
- You consistently deliver robust, scalable features across the stack.
- You improve system quality through strong design, testing, and code review practices.
- You help the team move faster by solving recurring engineering problems.
- You collaborate effectively across teams to improve product quality and reliability.
CHI: $110,000-$160,000
NYC: $125,000-$175,000
The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Skills Required
- A few years of experience working on software development teams
- Experience contributing to technical analysis, system design, tradeoff evaluation, and engineering best practices
- Understanding of distributed and event-based architecture
- Experience working in fast-paced, agile environments
- Ability to troubleshoot roadblocks, write documentation, and coordinate cross-team collaboration
- Experience mentoring junior team members
- Experience with Docker
- Experience with AWS or GCP
- Experience with Python, Spark, dbt, SQL, or Airflow
- Experience in biotech, genomics, or precision medicine
Tempus AI Compensation & Benefits Highlights
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Healthcare Strength — Healthcare is considered solid, with PPO coverage often described as good and medical, dental, and vision options broadly available. Feedback suggests the overall health offering is a relative strong point despite mixed comments on premiums.
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Leave & Time Off Breadth — Time off is frequently characterized as flexible, with reports of unlimited or generous PTO in many corporate roles. Feedback suggests policies can vary by team, but the offering is generally viewed favorably.
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Wellbeing & Lifestyle Benefits — Workplace perks such as free meals/snacks, on-site amenities like a barista, gym discounts, and commuter benefits are commonly highlighted. Feedback suggests these lifestyle benefits add day-to-day value, especially at larger offices.
Tempus AI Insights
What We Do
We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time, connect patients with therapies and clinical trials, and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data, Tempus partners with more than half of U.S. oncologists and the majority of the top 20 global pharma companies. Our teams are pioneering work across oncology, neurology, psychiatry, cardiology, and beyond—transforming how care is delivered and therapies are developed. At Tempus, every role contributes to our mission: to help each patient benefit from the experiences of those who came before. For more information, visit tempus.com.
Why Work With Us
We’re looking for people who can change the world. People who question the status quo and refuse to shy away from tough problems. For builders who are never done building, and the learners who are never done learning. Passionate individuals with undying curiosity who want to take on one of the greatest challenges humanity has ever faced—head on.
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Tempus AI Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
Most of the team follows a hybrid policy, with some roles allowing for a fully remote arrangement and some roles being onsite only.
































