We are seeking a motivated and detail-oriented Senior Research Technologist to join a translational research laboratory focused on neuroimmunology, biomarker discovery, and development of advanced immunologic assays. The individual in this role will support ongoing research studies through hands-on laboratory work, experimental organization, data analysis, and maintenance of accurate laboratory records.
The ideal candidate is highly organized, dependable, intellectually curious, and comfortable working in a fast-paced research environment that bridges basic science and clinical applications.
Primary Responsibilities
- Perform routine and advanced laboratory procedures in support of research studies and assay development
- Prepare reagents, buffers, samples, and laboratory materials
- Conduct pipetting-intensive experiments and 96-well plate-based assays with precision and consistency
- Maintain accurate and organized laboratory notebooks and experimental records
- Assist with optimization, validation, and troubleshooting of laboratory assays
- Process and organize biological specimens according to laboratory protocols
- Analyze and organize experimental data using Excel, RStudio, or related software tools
- Assist with inventory management, ordering supplies, and maintaining laboratory organization
- Collaborate with laboratory staff, trainees, and investigators on ongoing projects
- Follow all laboratory safety, biosafety, and quality control procedures
Desired Characteristics
- Strong problem-solving and troubleshooting abilities
- Ability to learn new techniques quickly
- Reliable, organized, and self-motivated
- Strong communication skills
- Interest in translational medicine, immunology, or biomarker research
Environment
This position involves substantial hands-on laboratory work and interaction with multidisciplinary research teams in a collaborative academic medical center environment. The role offers opportunities to develop advanced laboratory and analytical skills while contributing to clinically impactful research projects.
QualificationsRequires bachelor's degree in biology, chemistry, or other relevant science with 4 years of research laboratory experience. Master's degree in biology, chemistry, or other relevant science preferred.
Strong Preference given to those who have:
- Prior hands-on laboratory bench experience
- Demonstrated proficiency with basic laboratory techniques and pipetting
- Experience working with 96-well plate-based assays or similar experimental workflows
- Strong organizational skills and attention to detail
- Ability to maintain thorough and accurate laboratory documentation
- Ability to work independently while also functioning effectively within a collaborative team environment
Preferred Qualifications
- Experience working with human cell lines
- Experience with flow cytometry
- Familiarity with immunologic or protein-based assays (ELISA, cell-based assays, immunofluorescence, etc.)
- Experience with data analysis using RStudio and/or Excel
- Prior exposure to translational, clinical, or neuroimmunology research environments
- Experience handling human biological specimens
About Us
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Skills Required
- Bachelor's degree in biology, chemistry, or other relevant science
- 4 years of research laboratory experience
- Follow all laboratory safety, biosafety, and quality control procedures
- Prior hands-on laboratory bench experience
- Demonstrated proficiency with basic laboratory techniques and pipetting
- Experience working with 96-well plate-based assays or similar workflows
- Strong organizational skills and attention to detail
- Ability to maintain thorough and accurate laboratory documentation
- Ability to work independently and effectively within a collaborative team
- Experience working with human cell lines
- Experience with flow cytometry
- Familiarity with immunologic or protein-based assays (ELISA, cell-based assays, immunofluorescence)
- Experience with data analysis using RStudio and/or Excel
- Prior exposure to translational, clinical, or neuroimmunology research environments
- Experience handling human biological specimens
- Master's degree in biology, chemistry, or other relevant science
Mayo Clinic Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Mayo Clinic and has not been reviewed or approved by Mayo Clinic.
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Retirement Support — A no-cost pension plus an employer-matched 403(b)/401(k) is positioned as a standout differentiator, offering strong long-term financial security. Feedback suggests this retirement combination elevates overall total rewards even when base pay is moderate.
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Healthcare Strength — Expanded medical networks, enhanced fertility coverage, and employer absorption of a plan year’s premium increases point to robust healthcare offerings. Feedback suggests annual updates maintain breadth and competitiveness of coverage.
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Parental & Family Support — Adoption assistance, dependent scholarships, child and elder-care resources, and EAP services provide meaningful family-oriented support. Feedback suggests these programs add tangible value beyond salary alone.
Mayo Clinic Insights
What We Do
Mayo Clinic is the first and largest integrated, not-for-profit medical group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of "the needs of the patient come first." More than 3,800 physicians and scientists and 50,900 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn., Jacksonville, Fla., and Scottsdale/Phoenix, Ariz. Mayo Clinic also serves over 70 communities through Mayo Clinic Health System with locations in MN, IA, and WI. Collectively, these locations care for more than 1 million people each year.
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