Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
As a Senior Product Manager for Tempus ECG-AI, you'll own the product roadmap for our ECG-AI offering—from algorithm scoping and development through commercial deployment into clinical workflows. You'll join a team with deep, proven experience bringing SaMD products to market, and you'll play a key role in shaping how AI-powered cardiac diagnostics are delivered at the point of care.
What You'll Do:
Develop and manage the product roadmap for the ECG-AI offering, ensuring alignment with Tempus' strategic goals across both the Technology and Science organizations.
Own the core ECG-AI device roadmap through the full SaMD lifecycle—including algorithm prioritization, scoping, development, clinical validation, design controls, risk management, regulatory clearance, clinical implementation, and post-market surveillance.
Drive the development of software that enables integration of the ECG-AI devices into clinical workflows, ensuring the approach to deployment of SaMDs leads to high impact, clinical outcomes for the patients at our partner health systems
Work closely with engineering, data science, clinical, and regulatory/quality teams to drive the planning, design, development, validation, and user experience of ECG-AI solutions.
Partner with leadership and cross-functional teams to develop project plans, set ambitious targets during quarterly planning, and take full accountability for achieving those results.
Oversee product releases to ensure the device and its integration are stable in production, scale reliably, and include ongoing monitoring of deployed machine learning model performance.
Distill, refine, and document technical and clinical requirements across teams, leveraging modern AI-assisted workflows to maximize precision and speed.
Lead operational change management for production changes, manage related workflow impacts, and triage product support requests.
Qualifications:
6+ years of experience in product management, including hands-on experience developing and launching a Software as a Medical Device (SaMD) product — through design controls, verification & validation, and regulatory clearance (e.g., FDA 510(k), De Novo, or equivalent). This experience is required.
Outstanding cross-functional leadership skills, with proven experience managing complex projects through influence — particularly across engineering and data science/ML teams.
A proven track record of translating scientific or clinical research into design and product decisions.
Demonstrated ability to manage several programs at once and work proactively to align multi-disciplinary stakeholders (engineering, science, regulatory, clinical).
Exceptional storytelling and communication skills, capable of explaining complex technical and regulatory concepts in simple terms.
AI-Fluency: Leverages Generative AI to accelerate individual productivity and applies a strategic vision for incorporating an agentic-first approach into product solutions.
A growth mindset and a desire to continuously learn.
Highly organized with strong attention to detail and a pervasive bias toward clarity and scalability.
Ability to thrive in a fast-paced environment.
Knowledge of healthcare data is ideal, and experience in cardiology or cardiac diagnostics specifically is a strong plus.
The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Skills Required
- Experience working with agile software development teams
- History of building and using product analytics to drive decisions (tools such as SQL, Tableau, Plotly)
- Experience with software development and project management tools (JIRA, Trello, etc.)
- Ability and interest to quickly ramp up on new concepts in genomics and oncology
- Excellent written and verbal communication skills; ability to translate among biologists, medical professionals, engineers, and data scientists
- 3+ years of technical experience in product management or building software in tech or biotech industry
Tempus AI Compensation & Benefits Highlights
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Healthcare Strength — Medical, dental, and vision insurance are standard and employer‑verified, complemented by life/disability coverage, HSA/FSA, mental health resources, and EAP. Company materials and verified listings indicate these core benefits are well established as of mid‑2026.
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Leave & Time Off Breadth — Vacation/Paid Time Off, Sick Leave, and Paid Holidays are explicitly offered on employer‑verified pages. Many roles are described as having flexible or unlimited PTO, though laboratory staff may follow separate policies.
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Wellbeing & Lifestyle Benefits — On‑site conveniences such as a cafeteria, stocked kitchens, and an on‑site barista are highlighted for select offices, alongside wellness initiatives, gym discounts, commuter benefits, and charitable matching. These day‑to‑day perks are emphasized on official culture/benefits pages and aligned third‑party summaries.
Tempus AI Insights
What We Do
We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time, connect patients with therapies and clinical trials, and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data, Tempus partners with more than half of U.S. oncologists and the majority of the top 20 global pharma companies. Our teams are pioneering work across oncology, neurology, psychiatry, cardiology, and beyond—transforming how care is delivered and therapies are developed. At Tempus, every role contributes to our mission: to help each patient benefit from the experiences of those who came before. For more information, visit tempus.com.
Why Work With Us
We’re looking for people who can change the world. People who question the status quo and refuse to shy away from tough problems. For builders who are never done building, and the learners who are never done learning. Passionate individuals with undying curiosity who want to take on one of the greatest challenges humanity has ever faced—head on.
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Tempus AI Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
Most of the team follows a hybrid policy, with some roles allowing for a fully remote arrangement and some roles being onsite only.
































