Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
Tempus is seeking a (Senior) Medical Director in Oncology to serve as the primary clinical partner for our Life Sciences account teams. This role bridges the gap between clinical oncology practice, real-world data, and biopharma drug development. You will partner with key accounts to provide strategic, proactive clinical guidance. You will translate complex oncologic concepts, patient care realities, and clinical trial challenges into actionable data and AI-driven solutions. The ideal candidate brings dedicated clinical experience in Gastrointestinal (GI) or Breast malignancies, combined with a strong understanding of how real-world evidence accelerates oncology pipelines.
Responsibilities
Build and execute holistic, long-term clinical strategies for assigned accounts, leveraging Tempus capabilities including multimodal real-world data (RWD) datasets, agentic AI tools, and clinical trial acceleration solutions.
Serve as the primary clinical peer to biopharma Clinical Directors, Medical Affairs leaders, and Translational Medicine executives, maintaining a proactive, structured cadence of engagement.
Develop indication-specific "battle decks" that map real-world standards of care, biomarker testing patterns, and unmet clinical needs directly against client pipeline assets.
Analyze client pipelines, clinical trial readouts, and investor relations materials to proactively anticipate client needs and formulate strategic account growth plans.
Synthesize medical conference updates (e.g., ASCO, ESMO, SABCS) into actionable client insights, advising biopharma partners on trial protocol design, cohort selection, and synthetic control arms.
Partner with internal teams on high-value client calls to communicate complex scientific and clinical solutions with authoritative credibility.
Act as an internal subject matter expert across Tempus products and services to ensure scientific accuracy, enhance product usability, and align service capabilities with evolving market needs.
Qualifications
Education & Clinical Practice: MD or DO required, with board certification/eligibility in Medical Oncology
Subspecialty Expertise: Strong clinical focus in Gastrointestinal (GI) or Breast cancers is highly preferred.
Biopharma & RWD Fluency: Proven ability to analyze biopharma drug pipelines, understand clinical trial design/regulatory pathways, and apply complex real-world datasets (NGS, clinical data)
Executive Presence: Track record of building trusted relationships with biopharma leadership, leading complex enterprise initiatives, and presenting to executive client teams.
#LI-NK1
#LI-REMOTE
$270,000-$350,000
The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Skills Required
- MD or DO degree
- Board certification or eligibility in Medical Oncology
- Ability to analyze biopharma drug pipelines
- Understanding of clinical trial design and regulatory pathways
- Ability to apply complex real-world datasets, including NGS and clinical data
- Track record of building trusted relationships with biopharma leadership
- Experience leading complex enterprise initiatives
- Experience presenting to executive client teams
- Strong clinical focus in gastrointestinal or breast cancers
What the Team is Saying
Tempus AI Compensation & Benefits Highlights
-
Healthcare Strength — Health coverage is described as comprehensive, including medical, dental, vision, life and disability insurance, plus mental‑health resources and HSA/FSA options, with core items employer‑verified in mid‑2026.
-
Leave & Time Off Breadth — Paid time off and parental leave are consistently part of the package, with parental leave commonly cited around three months and related pages noted as recently employer‑verified.
-
Wellbeing & Lifestyle Benefits — Everyday perks such as commuter benefits, on‑site meals and coffee programs, gym discounts, charitable matching, ERGs, pet insurance, and team events are widely highlighted, with some amenities available in select offices.
Tempus AI Insights
What We Do
We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time, connect patients with therapies and clinical trials, and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data, Tempus partners with more than half of U.S. oncologists and the majority of the top 20 global pharma companies. Our teams are pioneering work across oncology, neurology, psychiatry, cardiology, and beyond—transforming how care is delivered and therapies are developed. At Tempus, every role contributes to our mission: to help each patient benefit from the experiences of those who came before. For more information, visit tempus.com.
Why Work With Us
We’re looking for people who can change the world. People who question the status quo and refuse to shy away from tough problems. For builders who are never done building, and the learners who are never done learning. Passionate individuals with undying curiosity who want to take on one of the greatest challenges humanity has ever faced—head on.
Gallery
Tempus AI Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
Most of the team follows a hybrid policy, with some roles allowing for a fully remote arrangement and some roles being onsite only.
