Location: London
Reporting to: SVP, Head of Human Resources
Job Summary
Orchard Therapeutics is a global biotechnology gene therapy company dedicated to transforming the lives of people affected by rare diseases through the development of innovative, potentially curative cell and gene therapies. Orchard has its global headquarters in London and is a wholly owned subsidiary of Kyowa Kirin, a Japan-based Global Specialty Pharmaceutical Company.
The Senior HR Business Partner (HRBP) is a critical strategic partner to C-level global functional leaders, providing expert advice, coaching and solutions across all aspects of the employee lifecycle. Reporting to the Head of HR, the HRBP will play a key role in shaping and importantly delivering people strategies that enhance organisational performance, capability and culture across a global, matrixed environment.
Key Elements and Responsibilities:
- Partner with senior, C-level executive leadership and global functional leaders to provide strategic HR guidance across all aspects of the employee lifecycle, including talent, performance, engagement and organisational effectiveness
- Build trusted relationships and coach leaders to enhance capability, leadership effectiveness and organisational performance
- Act as a strategic partner in hiring, working with leaders and Talent Acquisition to define workforce needs, guide selection decisions and ensure high-quality, timely hiring outcomes
- Drive annual talent management processes, including goal setting, talent and succession reviews, performance management and compensation planning in collaboration with Global Rewards
- Develop and implement business-aligned HR strategies that support organisational goals, growth and transformation
- Contribute to the development of the HR function by coaching team members and supporting the Head of HR in building organisational capability
- Ensure effective utilisation and continuous improvement of HR systems, promoting data accuracy and insight-driven decision making
- Lead employee relations matters, ensuring appropriate handling, resolution and risk mitigation
- Monitor external trends and best practices to inform HR strategy and continuous improvement
- Ensure compliance with applicable employment legislation, policies and procedures
Requirements
Experience, skills and knowledge required:
- Significant global HR generalist experience, ideally within a complex, matrixed, international organisation
- Proven track record as an HRBP, influencing senior leaders to enhance organisational performance and drive change
- Strong business acumen, with the ability to influence executive and functional leadership on people-related matters in alignment with business priorities and performance outcomes
- Strong working knowledge of HR practices and employment frameworks across multiple geographies, with the ability to navigate regional nuances
- Demonstrated ability to build credible, trusted relationships and operate effectively at all organisational levels
- Skilled in coaching, influencing and constructively challenging leaders to enhance capability, engagement and performance
- Ability to translate business strategy into pragmatic, people-focused solutions and actions
- Strong analytical and problem-solving skills, with the ability to leverage data to inform decision-making
- Proficient in HR systems and technologies, with a focus on data integrity and continuous process improvement
- Highly organised with strong attention to detail and the ability to manage competing priorities
- Excellent communication skills, with the ability to convey complex information clearly and effectively
- Comfortable operating both strategically and hands-on in a fast-paced, evolving environment
- Experience within the biotechnology, biopharmaceutical or healthcare industry is preferred
Education
Bachelor’s degree (or equivalent) required, preferably in Human Resources, Business Administration or a related field, with a recognised professional HR qualification (e.g. CIPD or equivalent)
Skills Required
- Significant global HR generalist experience
- Proven track record as an HRBP
- Strong business acumen
- Strong working knowledge of HR practices
- Ability to build credible relationships
- Skilled in coaching and influencing leaders
- Strong analytical and problem-solving skills
- Proficient in HR systems and technologies
- Bachelor's degree in HR, Business Administration or related field
What We Do
At Orchard Therapeutics, our vision is to end the devastation caused by genetic and other severe diseases. We aim to do this by discovering, developing and commercializing new treatments that tap into the curative potential of hematopoietic stem cell (HSC) gene therapy. In this approach, a patient’s own blood stem cells are genetically modified outside of the body and then reinserted, with the goal of correcting the underlying cause of disease in a single treatment. In 2018, the company acquired GSK’s rare disease gene therapy portfolio, which originated from a pioneering collaboration between GSK and the San Raffaele Telethon Institute for Gene Therapy in Milan, Italy. Today, Orchard is advancing a pipeline spanning pre-clinical, clinical and commercial stage HSC gene therapies designed to address serious diseases where the burden is immense for patients, families and society and current treatment options are limited or do not exist. Orchard has its global headquarters in London and U.S. headquarters in Boston. For more information, please visit www.orchard-tx.com,







