As a Senior Data Analytics Engineer in Operational Intelligence, you will bridge Data Engineering, Data Science, and Analytics to curate and transform raw operational and laboratory data into BI-ready datasets and scalable data products. You will collaborate across Software, Operations, Research, Development, and Commercial to design and sustain a robust data ecosystem, while performing analysis and building and maintaining dashboards and analytical tools that monitor high-throughput lab processes. In this strategic, hands-on role, you will ensure the accuracy, accessibility, and utility of data and reporting systems that are critical to lab efficiency, traceability, and product quality, delivering trusted insights that drive measurable business value in a rapidly growing environment.
This role is based at our Durham, North Carolina, office. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site.
Responsibilities:
Build, evolve, and support dashboards, reports, and real-time monitoring tools for functional teams and executives that clearly communicate findings and drive data-informed decisions.; enable self-serve analytics and automate common ad hoc requests.
Implement and continuously improve process monitoring systems (e.g., SPC, automated controls, alerting) to track and stabilize process health.
Define, govern, and report KPIs for throughput, quality, efficiency, and compliance; proactively surface trends, anomalies, and risks.
Develop and deploy predictive analytics, trend analyses, and models to anticipate process, equipment, and quality issues; partner with Data Science on model integration and deployment.
Collect, cleanse, and analyze process and production data from high-throughput lab environments; ensure timely, reliable access to accurate datasets.
Provide rapid data extracts and tailored analyses to expedite troubleshooting, containment, and root-cause investigations.
Ensure data quality and integrity through robust testing, validation, lineage, and observability; establish and monitor SLAs for critical datasets.
Maintain comprehensive process documentation compliant with ISO, CLIA, CAP, NYS, GMP, and FDA requirements; ensure monitoring and reporting systems are audit-ready.
These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.
Required Qualifications:
Bachelor’s degree in Computer Science, Statistics, Informatics, Information Systems, Engineering, Data Science, Life Sciences, or a related quantitative field.
5+ years of relevant experience as a data analyst, analytics engineer, or data engineer delivering production-grade datasets, dashboards, and reports.
3+ years of data modeling experience (dimensional/semantic).
2+ years building dashboards and reports in a modern BI platform (e.g., Tableau).
Proficiency in SQL and at least one programming language (Python or R).
Hands-on experience with AWS analytics services (e.g., Redshift, S3, Glue, Managed Airflow) and/or Snowflake.
Experience working with SaaS application data sources (e.g., NetSuite, Salesforce, Workday, Coupa).
Proven expertise in process analytics, SPC, statistical methods, and root-cause analysis (e.g., JMP, Minitab; SQL; Python/R).
Demonstrated ability to collaborate with stakeholders and system users to deliver robust solutions and measurable results.
Experience in regulated life sciences/biotech environments and familiarity with clinical laboratory operations.
Preferred Qualifications:
5+ years of laboratory operations experience in regulated medical device, diagnostics, or biotechnology settings.
- Master’s preferred.
Experience deploying and scaling process monitoring in high-throughput or automated environments.
Knowledge of end-to-end clinical lab workflows (sample shipment; pre-analytical, analytical, and post-analytical phases).
Strong understanding of regulatory and QMS frameworks (GMP, ISO 13485, ISO 15189, CLIA, CAP, NYS, FDA).
Excellent leadership, communication, and cross-functional collaboration skills
What the Team is Saying
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GRAIL Compensation & Benefits Highlights
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Healthcare Strength — Health coverage is described as complete across medical, dental, and vision with multiple plan options and added mental‑health and disability support. Additional provisions such as abortion travel benefits reinforce the depth of the healthcare offering.
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Equity Value & Accessibility — Equity is positioned as a meaningful part of total rewards via new‑hire grants, inducement awards, and a discounted ESPP. Compensation materials also highlight equity alongside bonuses and structured market benchmarking.
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Leave & Time Off Breadth — Policies emphasize flexible time off, paid holidays, and company breaks, with a defined parental‑leave program. International entitlements are specifically called out, indicating breadth across regions.
GRAIL Insights
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What We Do
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is using the power of high-intensity sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop and commercialize pioneering products.
Why Work With Us
Everything we do is guided by our mission to detect cancer early, when it can be cured. It’s the reason we’re here, and it’s no small task. The right people make all the difference. That’s why we’re looking for those who strive to share their knowledge, contribute their skills, inspire each other and commit to something bigger than themselves.
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GRAIL Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
GRAIL has a variety of work types depending on the roles. Some roles are onsite like a lab role, some are fully remote like our Galleri Sales Consultant roles. Others are hybrid with 2-3 days onsite. Typically Tuesday and Thursday.
