Senior Automation Engineer, Laboratory Automation – Analytical Sciences

Posted 8 Days Ago
Be an Early Applicant
Santa Monica, CA, USA
In-Office
103K-155K Annually
Senior level
Biotech • Pharmaceutical
The Role
Designs, programs, implements, and optimizes laboratory automation for cell-based, immunological, and genomic assays. Maintains Hamilton liquid-handling systems, develops automated workflows, troubleshoots equipment, and transfers methods to quality control teams and external partners. Creates technical documentation, trains laboratory staff, evaluates emerging technologies, and collaborates with scientists, engineers, IT, and stakeholders to improve assay robustness, workflow efficiency, and data quality in a regulated cell therapy environment.
Summary Generated by Built In

We are seeking an accomplished Senior Automation Engineer to join the Laboratory Automation team within Analytical Sciences. This fully on-site role is based in Santa Monica, California. Reporting to the Associate Director of Laboratory Automation, you will develop, implement, and optimize automation solutions for cell-based, immunological, and genomic assays. You will own deliverables, maintain momentum, and proactively communicate progress, risks, decisions, and resource needs. The role combines hands-on engineering with project execution and stakeholder management to improve assay robustness, workflow efficiency, and data quality for novel engineered cell therapy products.


Key Responsibilities 


  • Design, build, and implement automation solutions for cell-based, immunological, and genomic assays 
  • Program, test, and maintain Hamilton VANTAGE and other automated liquid-handling workstations 
  • Develop and optimize liquid-handling scripts for complex bioassay workflows 
  • Partner with scientists, engineers, and IT specialists to translate manual processes into robust automated workflows 
  • Troubleshoot, maintain, and continuously improve automated systems to ensure reliable performance 
  • Support the transfer of automated assay methods to Quality Control teams and external partners 
  • Create and maintain SOPs, user guides, and technical reports 
  • Train laboratory personnel on automation systems, workflows, and best practices 
  • Evaluate emerging automation technologies and recommend opportunities for implementation 

Qualifications 


  • Bachelor’s or master’s degree in bioengineering, biotechnology, mechanical engineering, electrical engineering, or a related field  of hands-on experience with laboratory automation systems 
  • Advanced expertise with Hamilton liquid-handling platforms and VENUS software 
  • Experience developing integrated automation workflows using scheduling software such as HighRes Cellario 
  • Proficiency in Python, C++, or a similar programming language 
  • Experience with cell culture, immunological assays, and flow cytometry 
  • Knowledge of GMP requirements and experience in a regulated environment 
  • Strong problem-solving skills, sound judgment, and attention to detail 
  • Excellent written, verbal, and technical communication skills 
  • Demonstrated ability to proactively communicate progress, risks, decisions, and resource needs 
  • Proven ability to prioritize competing work, maintain focus, own deliverables, and provide clear, timely progress updates 
  • Ability to balance hands-on engineering with project execution, stakeholder alignment, and business priorities 

Preferred Qualifications 


  • Knowledge of cell therapy development and manufacturing processes 
  • Familiarity with QbD principles 
  • Experience applying DoE approaches to method development 
  • Experience with data analysis and visualization tools such as Prism, JMP, or FlowJo 
  • Experience with computer-aided design tools such as AutoCAD or Fusion 360 
  • Experience using 3D printing for laboratory automation applications 
  • Experience with LIMS such as Benchling or Labguru, and their integration with laboratory automation schedulers 

The annual base pay (or hourly rate of compensation) for this position ranges from $103,286.40 to $154,929.60. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. 

Date Posted

16-Oct-2026

Closing Date

29-Oct-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Skills Required

  • Bachelor's or master's degree in bioengineering, biotechnology, mechanical engineering, electrical engineering, or a related field
  • Hands-on experience with laboratory automation systems
  • Advanced expertise with Hamilton liquid-handling platforms and VENUS software
  • Experience developing integrated automation workflows using scheduling software such as HighRes Cellario
  • Proficiency in Python, C++, or a similar programming language
  • Experience with cell culture, immunological assays, and flow cytometry
  • Knowledge of GMP requirements and experience in a regulated environment
  • Strong problem-solving skills, sound judgment, and attention to detail
  • Excellent written, verbal, and technical communication skills
  • Ability to proactively communicate progress, risks, decisions, and resource needs
  • Ability to prioritize competing work, maintain focus, own deliverables, and provide timely progress updates
  • Ability to balance hands-on engineering with project execution, stakeholder alignment, and business priorities
  • Knowledge of cell therapy development and manufacturing processes
  • Familiarity with QbD principles
  • Experience applying DoE approaches to method development
  • Experience with Prism, JMP, or FlowJo
  • Experience with AutoCAD or Fusion 360
  • Experience using 3D printing for laboratory automation applications
  • Experience using LIMS such as Benchling or Labguru and integrating them with laboratory automation schedulers

AstraZeneca Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AstraZeneca and has not been reviewed or approved by AstraZeneca.

  • Fair & Transparent Compensation — Pay is considered competitive across many roles when total rewards are factored in. Senior scientific and leadership bands are described with high ranges that reinforce competitiveness at upper levels.
  • Strong & Reliable Incentives — Bonuses, equity eligibility in many salaried roles, and solid sales on‑target earnings with upside are emphasized as meaningful parts of compensation. These elements boost overall value even where base pay is not the very highest.
  • Retirement Support — A 401(k) program with a strong company match and immediate vesting is repeatedly cited as a standout. Generous retirement support is viewed as enhancing the total package relative to peers.

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The Company
HQ: Gaithersburg, MD
70,000 Employees
Year Founded: 1999

What We Do

We're transforming the future of healthcare by unlocking the power of what science can do for people, society and the planet.

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