Who We Are
Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.
Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.
What Matters to Us
Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.
Arcellx Core Values
- Character: Committed to always doing what’s right.
- Audacity: Willing to challenge convention and share candid feedback with others.
- Determination: Curious and self-motivated. Always looking to improve and learn.
- Collaboration: "No job is too small" mentality. Humble and willing to help others.
- Originality: Will bring your unique perspective to the table and respect a diverse set of views and backgrounds.
The “Fine Print” – What You’ll Do
- Serve as a biophysics SME (subject matter expert) in CMC activities including pre-formulation study, formulation development, in-process monitoring, product characterization, particle characterization and investigation.
- Collaborate with a dynamic and engaging team of Arcellx scientists and CDMO partners to perform biophysical characterization and thermodynamic analysis on protein and lentivirus products.
- Build strategies for protein or virus product quality analytical testing throughout the product lifecycle development.
- Participate in designing long-term stability studies per regulatory guidelines and perform stability data trending analysis for drug substances, drug products and reference standards.
- As a key contributor, design and coordinate accelerated and stressed stability study for manufacturability assessment, analytical method development, formulation development, CQA assessment and comparability study.
- Author and review technical documents.
- Perform and troubleshoot analytical assays to support CMC and some research activities.
- Present scientific study design and findings at internal and external meetings.
Skills and Experience We Look For
- Bachelor’s degree with 10+ years of relevant work experience, or master’s degree with 8+ years’ experience, or PhD in relevant scientific discipline with 2+ years of postdoc or industry experience on protein or virus analysis.
- Solid background knowledge and practical experience in biophysical techniques to characterize aggregates, subvisible and visible particles in proteins and/or viral vector products, such as flow imaging techniques, HIAC, NTA, SEC-MALS, FFF-MALS, DLS/SLS, etc.
- Hands-on experience in thermodynamic analysis (DSC or DSF) to support formulation development or product characterization.
- Prior experience in particle characterization and investigation in the late stage of CMC development is highly desired.
- Experience in drafting and reviewing technical documents including analytical method SOPs, characterization protocols and reports.
- Experience in applying Design of Experiment (DOE) and other appropriate statistics approaches during formulation development, analytical method development and robustness study is preferred.
- Excellent collaborator with strong communication skills.
- Proven self-starter with a high attention to scientific details and strong problem-solving skills.
Rewards at Arcellx
Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits.
In addition to a competitive base salary, our compensation package includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required.
Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more.
Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to www.arcellx.com.
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What We Do
We are a clinical-stage biotechnology company reimagining cell therapy through the development of innovative immunotherapies.
