Arcellx
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As a Principal Scientist on the Translational team, you'll be responsible for driving the development and execution of translational strategy for projects moving from discovery to early clinical development, with a focus on hematologic malignancy programs. You'll lead the implementation of clinical biomarker strategies, communicate translational updates, define novel mechanisms of resistance, and contribute to preclinical to clinical translation of pipeline assets.
The Senior Analytical Scientist I at Arcellx will serve as a biophysics subject matter expert in CMC activities, collaborate with teams for biophysical characterization, design long-term stability studies, troubleshoot analytical assays, and present study findings at meetings.
Participate in technical transfers, lead manufacturing deviations investigations, analyze process data, engage with external partners, support change management, and travel up to 30%.
Collaborate with project team members and CROs to generate clinical protocol, perform analysis, interpret study results, manage CRO, validate key efficacy endpoints analyses, and support ongoing publication tasks in the field of biostatistics for a clinical-stage biotechnology company.
Responsible for developing and managing the supply chain for Arcellx cell therapy pipeline, including strategic sourcing, material controls, warehousing, and business systems. Enhances operational controls and efficiencies to advance cell therapies through clinical trials and to patients in need.
As a Principal QC Specialist at Arcellx, you will collaborate with teammates to develop and build a new QC testing laboratory, establish sample management and chain of custody program, perform technical review of GMP method qualification, and lead and approve QC GMP Quality Management Systems. You will be a subject matter expert for the QC assays, especially molecular-based assays.
As the Director, Program Lead, you will be responsible for managing pipeline projects from clinical candidate nomination through clinical proof of concept. You will also be accountable for developing and driving project strategy, managing the project timeline and budget, and ensuring adequate clinical supply. Your expertise in developing immunotherapies for cancer and your skills in project management and trade-off decisions will be crucial in maximizing the likelihood of clinical and commercial success.
As an Associate Scientist in our Cell Biology group, you will contribute to the development of novel cell-based therapies by conducting lab-based research activities, analyzing data, and assisting in the preparation of technical reports. This role requires expertise in handling human immune cells, conducting immune assays, and utilizing various laboratory techniques.