Job Description
Vertex is seeking a highly skilled Senior Azure DevSecOps Engineer to design, implement, secure, and optimize cloud platforms that power enterprise software, data, and AI-driven solutions. This role will be a key technical contributor supporting VaiDA and other strategic initiatives built on Microsoft Azure, Microsoft Foundry, and related cloud technologies.
Working closely with software engineers, cloud architects, information security teams, and business stakeholders, this individual will drive the adoption of DevSecOps best practices, cloud automation, infrastructure as code, and secure software delivery pipelines. The ideal candidate combines deep Azure expertise with a strong security mindset and a passion for building scalable, resilient, and highly automated platforms.
Key Duties and Responsibilities- Design, implement, and manage secure, scalable Azure cloud infrastructure supporting enterprise applications, data platforms, and AI-enabled solutions.
- Build, enhance, and maintain CI/CD pipelines to improve software delivery speed, reliability, quality, and security.
- Embed security controls throughout the software development lifecycle through DevSecOps practices, automated security scanning, policy enforcement, and compliance monitoring.
- Develop and maintain infrastructure as code solutions using Terraform, Bicep, ARM templates, or similar technologies.
- Partner with Information Security teams to implement and continuously improve identity management, secrets management, vulnerability management, network security, and cloud governance controls.
- Support and enhance Microsoft Foundry, Azure AI, and related Azure platform services used to develop and deploy AI-powered applications and agents.
- Establish platform engineering standards, deployment guardrails, and reusable automation patterns that enable secure self-service capabilities for engineering teams.
- Implement observability, monitoring, logging, alerting, and operational excellence practices to improve platform reliability and performance.
- Lead troubleshooting and root cause analysis efforts for complex cloud infrastructure, deployment, and security issues.
- Collaborate with software engineering teams to modernize application deployment architectures and promote cloud-native engineering practices.
- Evaluate and implement emerging Azure and security technologies to improve platform capabilities and reduce operational risk.
- Mentor engineers and promote DevSecOps and cloud security best practices across the organization.
- Deep expertise with Microsoft Azure cloud services and enterprise-scale cloud operations.
- Strong experience with Azure DevOps, GitHub Actions, CI/CD automation, and release management.
- Expertise in infrastructure as code, including Terraform, Bicep, ARM templates, or equivalent technologies.
- Strong understanding of cloud security principles, including Zero Trust, Identity and Access Management (IAM), Privileged Access Management (PAM), secrets management, encryption, and vulnerability remediation.
- Experience implementing security tooling and controls within automated delivery pipelines.
- Hands-on experience with container technologies, including Docker and Kubernetes.
- Strong scripting and automation skills using PowerShell, Python, Bash, or similar languages.
- Experience with monitoring, observability, incident management, and platform reliability practices.
- Ability to communicate complex technical concepts to both technical and non-technical audiences.
- Strong problem-solving skills and a continuous improvement mindset.
- Demonstrated ability to work effectively in highly collaborative, cross-functional environments.
- Bachelor's degree in Computer Science, Information Systems, Engineering, or a related field, or the equivalent combination of education and experience.
- Typically requires 8+ years of experience in cloud engineering, DevOps, platform engineering, site reliability engineering, or related technical disciplines.
- 5+ years of hands-on experience supporting production workloads in Microsoft Azure.
- Experience building and operating enterprise-scale CI/CD platforms and cloud infrastructure.
- Experience implementing cloud security controls and DevSecOps practices within regulated or security-conscious environments preferred.
- Microsoft Azure certifications (Azure Solutions Architect, Azure Security Engineer, Azure DevOps Engineer, or equivalent) strongly preferred.
- Experience with Microsoft Foundry, Azure AI Services, Azure OpenAI, or related AI platform technologies strongly preferred.
- Experience supporting AI, machine learning, or generative AI platforms.
- Experience operating in pharmaceutical, biotechnology, healthcare, or other regulated environments.
- Experience establishing engineering standards and platform governance across multiple development teams.
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Pay Range:
$95,200 - $142,800Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
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Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
Skills Required
- Proficiency in Java, Python, C#, and JavaScript.
- Expertise in software architecture and design patterns.
- Experience with Agile and DevOps practices.
- Strong understanding of database systems and data structures.
- Bachelor's degree in Computer Science, Software Engineering, or related field.
- 1 year of experience in software development roles.
Vertex Pharmaceuticals Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Vertex Pharmaceuticals and has not been reviewed or approved by Vertex Pharmaceuticals.
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Parental & Family Support — Policies provide 12 weeks of 100% paid bonding leave for all U.S. parents with additional fully paid time for birth parents. Family-forming supports include adoption and surrogacy assistance, fertility options like IVF and egg cryopreservation, breast‑milk shipping, subsidized childcare, backup care, and a DCFSA match.
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Leave & Time Off Breadth — Time off includes roughly four weeks of vacation, 13 holidays, sick time, and two companywide shutdowns (summer and year‑end). Some roles also include flexible or unlimited time off and paid volunteer time.
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Retirement Support — Programs include a 401(k) plan with employer contributions and an employee stock purchase plan. Filings describe employer contributions occurring in company stock, supporting long‑term ownership.
Vertex Pharmaceuticals Insights
What We Do
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development. Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.
