Jobs at Vertex Pharmaceuticals

Manages financial planning, budgeting, forecasting, long-range planning, and performance analysis for clinical development functions. Builds financial models, analytics, reporting, scenarios, and business cases to support investment decisions and identify risks and opportunities. Partners with clinical and finance leaders, drives process improvement across the CFO organization, and provides financial insight to guide business decisions.

Leads marketing automation, customer data activation, CDP operations, and OneTrust consent integration. Translates business needs into requirements, user stories, backlogs, and acceptance criteria; prioritizes initiatives; coordinates DTE and vendors; oversees testing, UAT, and launches; and ensures privacy and data-governance compliance. The role optimizes segmentation, journey orchestration, personalization, platform performance, and AI-enabled automation while developing scalable processes and maintaining audit-ready traceability.

Leads FP&A for assigned G&A functions, including annual budgeting, forecasting, long-range planning, workforce planning, variance analysis, financial reporting, and close support. Partners with senior leaders to provide financial counsel, identify performance drivers, allocate resources, and influence business decisions. Builds reporting and analytics, supports financial controls, and drives process improvement through automation, AI-enabled analytics, and visualization tools.

Leads an interdisciplinary automation engineering team developing, deploying, qualifying, and improving automated manufacturing equipment for cell and genetic therapies. Oversees mechanical, electrical, controls, robotics, vision, vendor, commissioning, validation, technology transfer, troubleshooting, and equipment strategy activities. Partners with manufacturing, quality, and vendors to integrate systems, manage documentation, support investigations, and deliver projects on schedule and within budget. The role requires strong regulatory, technical, leadership, and project management expertise.

Lead end-to-end delivery of technology initiatives for Legal, Compliance, and Corporate Communications. Partner with stakeholders and vendors to translate business needs into scalable SaaS solutions, manage integrations, risk, change, and compliance, and contribute to roadmap, governance, and continuous improvement efforts in a regulated environment.

Administers Vertex’s enterprise collaboration, videoconferencing, AV, webcast, Unified Communications, and event technology ecosystem. Responsibilities include platform configuration, access and security, conference-room lifecycle management, executive event support, Tier 3 troubleshooting, integrations, automation, AI-enabled meeting capabilities, monitoring, governance, documentation, training, and service optimization. The role requires hybrid or on-site support at the Boston Seaport office.

Leads a portfolio of AI-driven workforce transformation initiatives, overseeing strategic prioritization, governance, roadmaps, financial management, risk, compliance, and value realization. Partners with executives and cross-functional stakeholders to manage delivery through waves and sprints, supports responsible AI and lifecycle oversight, coordinates vendors and enterprise platforms, and coaches project and program managers. The role requires translating complex AI, data, technology, and regulatory concepts for technical and non-technical audiences.

Supports assigned business functions through budgeting, forecasting, long-range planning, financial modeling, KPI analysis, variance tracking, headcount planning, and business-case evaluation. Participates in accounting close and SOX controls, identifies financial risks and value drivers, communicates insights to management, and supports continuous improvement initiatives within the Finance organization.

Leads Vertex’s ICX data, analytics, AI, decisioning, and agentic strategy. Oversees data products, predictive models, AI agents, measurement, governance, Responsible AI, vendor partnerships, and commercial value realization. Partners with technology, commercial, legal, medical, regulatory, privacy, and compliance stakeholders while building and developing a multidisciplinary team of approximately nine direct reports.

Provide functional and technical support for Oracle E-Business Suite, especially Oracle Process Manufacturing, Supply Chain Management, and Materials Management modules. Partner with stakeholders to gather requirements, design solutions, create specifications, configure systems, and deliver integrations and enhancements. Lead Oracle EBS technical projects in GxP environments while collaborating with developers and technology teams to maintain compliant, scalable systems.

Leads US Commercial Finance as a strategic partner to senior commercial executives. Oversees budgeting, long-range planning, forecasting, revenue and expense management, scenario analysis, investment decisions, and value creation. Guides resource allocation, launch readiness, portfolio optimization, and commercial strategy while managing enterprise risks. Leads and develops a finance team, collaborates across global finance and corporate functions, and influences executive decision-making in a highly regulated biotechnology environment.

Leads workforce planning analytics, forecasting, executive reporting, conversational self-service analytics, applied research, and AI transformation measurement. Builds automated reporting and analytical products using Python or R, SQL, and AI tools; develops governed semantic models and data products; monitors organizational design and data quality; and advises senior leaders on workforce and investment decisions.

Leads R&D financial planning and analysis for Discovery Research and Preclinical Sciences. Partners with senior scientific leaders on budgeting, forecasting, scenario modeling, portfolio investment, resource allocation, reporting, controls, and research collaboration finances. Oversees AI-enabled finance transformation, dashboards, automation, and financial governance while managing two direct reports. Supports CRO and vendor spend, FTE planning, accounting processes, and executive decision-making across early-stage drug discovery portfolios.

Acts as regional general counsel for Vertex’s CEEM operations, advising business leaders on regulatory, marketing, market access, pricing, reimbursement, supply chain, patient advocacy, safety, and government affairs matters. Drafts and negotiates access-program and commercial contracts, supports expansion into new therapy areas, manages legal staff, and provides strategic counsel across multiple countries. Requires substantial biopharmaceutical, law firm, or government legal experience, qualification to practice in a relevant country, and fluency in English and German.

Leads business analysis and technology solution delivery for Vertex’s Cell and Gene Therapy commercial organization. Responsibilities include requirements gathering, process mapping, solution design, AI and automation use cases, stakeholder workshops, testing, training, change management, compliance alignment, and documentation. The role supports patient services, order management, field enablement, analytics, data integration, and commercial platforms while coordinating with product, engineering, data, and vendor teams.

Oversee revenue accounting for order-to-cash activities, including product revenue, accounts receivable, gross-to-net accruals, collections, credit assessment, reconciliations, month-end close, and financial reporting. Partner with commercial, market access, trade, distribution, and external service-provider teams. Lead process improvements, automation, analytics, forecasting support, systems development, and policy enhancements while reviewing team work as needed.

Serve as a technical business partner delivering and supporting COTS and custom PPM solutions. Lead evaluation, selection, implementation, lifecycle planning, vendor management, and compliance activities. Drive process improvements, align technology to business strategy, manage delivery for large complex projects, and collaborate with compliance, audit, and QA teams. Support Agile delivery and oversee outsourced/managed services.

Owns global logistics performance reporting, KPI dashboards, TMS master data governance, annual budgeting, freight accruals, and variance analysis. Partners with logistics, finance, procurement, data, and technology teams to improve data products, automate reporting, maintain data quality, and support digital transformation. Presents performance and financial insights to senior leadership, drives cross-functional alignment, and serves as the logistics end-user representative for analytics requirements.

Leads Procure-to-Pay process and platform enablement across requisitioning, purchasing, receiving, invoicing, matching, supplier information management, controls, and operational payment handoffs. Owns the P2P roadmap, continuous improvement, release readiness, UAT, change management, supplier data quality, and cross-functional collaboration with Procurement, Finance, IT, Data, and Operations. Drives automation, AI adoption, compliance, user experience, and stable financial execution.

Leads Vertex’s global trade compliance strategy, processes, systems, and regulatory activities across pharmaceutical supply chains and international markets. Oversees customs declarations, export controls, licensing, tariff optimization, trade agreements, compliance metrics, CAPA, and managed service providers. Partners cross-functionally with Supply Chain, Legal, Finance, Tax, Regulatory, Technology, and other stakeholders while developing high-performing global teams and scalable solutions.