Jobs at Vertex Pharmaceuticals

Leads workforce planning analytics, forecasting, executive reporting, conversational self-service analytics, applied research, and AI transformation measurement. Builds automated reporting and analytical products using Python or R, SQL, and AI tools; develops governed semantic models and data products; monitors organizational design and data quality; and advises senior leaders on workforce and investment decisions.

Analyzes complex quality and operational datasets, identifies trends, develops metrics, reports, visualizations, and data collection systems, and supports data-driven decision-making. The role documents data lifecycles and sources, advises business partners on data models and analysis, and contributes to continuous improvement initiatives within a regulated pharmaceutical or biotechnology environment.

Leads commercial training strategy and execution for a biotechnology organization. Develops learning programs, conducts needs and performance analyses, facilitates onboarding and advanced training, manages budgets and training portfolios, leads scientific product discussions, and mentors a team. Partners cross-functionally to improve commercial capabilities and workplace performance.

Conduct analytical chemistry research for small-molecule pharmaceutical development programs, including drug substance and product characterization, stability testing, data interpretation, method validation, and troubleshooting. Design experiments, maintain laboratory records, support GMP-friendly methods, collaborate on cross-functional development teams, and provide recommendations for project decisions. The role may also mentor junior staff and requires expertise in HPLC, GC, Karl Fischer, and related pharmaceutical analysis techniques.

Performs statistical analyses supporting clinical trials, observational studies, and real-world data investigations within Global Medicines Development and Affairs. Develops statistical analysis plans, protocols, sample size estimates, randomization plans, data review materials, and clinical study reports. Collaborates with statistical programmers and cross-functional teams to deliver high-quality analyses, contributes to publications, and applies statistical methods in drug development under guidance on complex issues.

Manages quality control laboratory programs supporting in-process, release, and stability testing. Oversees assay readiness, training, sample management, data review, reporting, investigations, laboratory metrics, and cGMP/GDP compliance. Troubleshoots analytical methods and equipment, approves data and SOPs, leads continuous improvement, and represents QC in cross-functional teams. Provides formal people management, coaching, and development on a third-shift schedule.

Supports automation systems in a GMP manufacturing facility, including PLC and HMI configuration, troubleshooting, testing, upgrades, industrial network integration, and data historian management. Maintains OT assets, patching records, backups, lifecycle plans, documentation, and validation records. Coordinates contractors, supports change control and commissioning, assesses risks, and collaborates with Manufacturing, Engineering, Quality, Validation, and vendors to ensure reliable, compliant equipment operation.

Supports implementation, maintenance, testing, and continuous improvement of digital manufacturing systems in a regulated pharmaceutical environment. Assists with MES configuration, user acceptance testing, defect tracking, requirements and validation documentation, incident monitoring, process documentation, training, and system enhancements. Partners with Manufacturing, Quality, Engineering, Supply Chain, and IT stakeholders while developing knowledge of GMP, GxP, electronic batch records, and computer system validation.

Leads US marketing strategy for Vertex’s IgAN portfolio, including brand strategy, lifecycle planning, promotional communications, forecasting, market insights, ROI evaluation, and cross-functional collaboration. Manages teams, contributes to portfolio strategy, oversees tactical execution, and supports financial and workforce responsibilities. Requires pharmaceutical marketing experience, strong analytical and forecasting skills, market research expertise, and substantial people-management experience.

Leads identification, contracting, onboarding, training, and operational readiness of Authorized Treatment Centers for Casgevy across the Netherlands and Belgium. Coordinates Vertex cross-functional teams and healthcare stakeholders, supports treatment-center activation and patient treatment journeys, resolves operational issues, oversees audits and training, tracks readiness objectives, and presents progress and recommendations to senior leaders. The role is commercial but non-promotional, focused on technical, operational, and process support for gene-editing therapy delivery.

Leads multi-product cell therapy manufacturing operations across three shifts at a Boston facility. Oversees compliant drug product production, inventory, resources, capacity, budgeting, quality events, regulatory inspections, digital systems, automation, and continuous improvement. Builds and develops manufacturing teams, manages talent and succession planning, maintains GMP compliance and training excellence, and partners with cross-functional and senior leadership stakeholders to ensure timely product delivery.

Leads R&D financial planning and analysis for Discovery Research and Preclinical Sciences. Partners with senior scientific leaders on budgeting, forecasting, scenario modeling, portfolio investment, resource allocation, reporting, controls, and research collaboration finances. Oversees AI-enabled finance transformation, dashboards, automation, and financial governance while managing two direct reports. Supports CRO and vendor spend, FTE planning, accounting processes, and executive decision-making across early-stage drug discovery portfolios.

Leads multi-product cell therapy manufacturing operations across three shifts, ensuring compliant production, inventory availability, capacity planning, quality, and regulatory readiness. Oversees manufacturing teams, resources, budgets, digital systems, automation, continuous improvement, training, talent development, and succession planning. Partners cross-functionally to execute strategic objectives, maintain GMP compliance, support FDA and EMA inspections, and deliver commercial therapies safely, efficiently, and on schedule.

Leads Vertex’s Commercial Analytics Center of Excellence, overseeing 20–25 employees and enterprise analytics across forecasting, market research, omnichannel, media, field, and sub-national analytics. Sets strategy, governance, operating models, vendor approaches, and prioritization while advising executives on launches, investment, market evaluation, field sizing, and revenue scenarios. Builds organizational capabilities, manages senior leaders and a $10M-plus growing budget, and partners across Commercial, Medical, HEOR, Market Access, Finance, and Supply Chain.

Leads Canadian cystic fibrosis marketing strategy and execution, including brand planning, product launches, agency management, sales initiatives, data and technology adoption, performance measurement, OPEX management, and cross-functional collaboration. Requires biopharmaceutical commercial experience, rare-disease marketing expertise, strong communication skills, and knowledge of Canadian regulatory and compliance requirements. The role travels 20–30% and is hybrid or on-site eligible.

Acts as regional general counsel for Vertex’s CEEM operations, advising business leaders on regulatory, marketing, market access, pricing, reimbursement, supply chain, patient advocacy, safety, and government affairs matters. Drafts and negotiates access-program and commercial contracts, supports expansion into new therapy areas, manages legal staff, and provides strategic counsel across multiple countries. Requires substantial biopharmaceutical, law firm, or government legal experience, qualification to practice in a relevant country, and fluency in English and German.

Leads business analysis and technology solution delivery for Vertex’s Cell and Gene Therapy commercial organization. Responsibilities include requirements gathering, process mapping, solution design, AI and automation use cases, stakeholder workshops, testing, training, change management, compliance alignment, and documentation. The role supports patient services, order management, field enablement, analytics, data integration, and commercial platforms while coordinating with product, engineering, data, and vendor teams.

Leads engineering development, optimization, validation, technology transfer, and lifecycle support for automated cell and genetic therapy manufacturing equipment and systems. Owns technical requirements, vendor selection, risk assessments, FAT/SAT, troubleshooting, investigations, CAPA, change control, and regulatory documentation. Partners cross-functionally with Manufacturing, Quality, Validation, Facilities, MSAT, and Project Management while mentoring engineers and delivering compliant, reliable, scalable manufacturing solutions.

Leads sophisticated statistical analyses for clinical trials, observational studies, and real-world data investigations. Authors statistical analysis plans, data review and dissemination plans, and contributes to clinical study reports and publications. Provides statistical leadership across cross-functional drug development teams, guides programming specifications and review, supports regulatory interactions, and applies advanced methods to study design and analysis. Requires independent strategic judgment, strong collaboration, and expertise in SAS, R, and pharmaceutical development.

Leads commercial analytical activities for cell and gene therapy products, including analytical method validation, technology transfer, testing oversight, continuous improvement, and lifecycle management. Authors and reviews SOPs, protocols, and technical reports while ensuring compliance with GMP and ICH, USP, and EMA requirements. Partners with analytical and process development, manufacturing, supply chain, quality teams, CDMOs, and contract laboratories to support launch readiness and commercial product lifecycle management.