Jobs at Vertex Pharmaceuticals

Lead and execute immunology research projects, design in vitro and in vivo experiments, develop and optimize disease models and translational assays, analyze data, present and publish findings, mentor junior scientists, and collaborate with cross-functional teams to advance therapeutic discovery.

The Administrative Assistant provides business support including scheduling meetings, organizing travel, processing purchase orders, and assisting with onboarding new employees.

The Associate Director will develop and execute digital marketing strategies for healthcare professionals, ensuring compliance and leveraging digital tools to enhance engagement and communication.

The Principal Research Scientist will lead the Dissolution Team in drug development, mentor members, conduct dissolution studies, and ensure compliance with regulatory guidelines.

The International Pharmacovigilance Manager oversees compliance with PV regulations for Vertex products in APAC, focusing on China, managing risks and maintaining documentation.

The Director in the Modeling CoE will lead the HEOR Modeling team in developing health economic models for HTA submissions, provide strategic support, and ensure quality assurance of models developed both in-house and by vendors.

Lead process automation and AI initiatives within the Commercial CGT DTE team by assessing workflows, implementing improvements, and managing change.

The International Pharmacovigilance Senior Manager leads compliance with PV regulations, manages contracts, coordinates with local representatives, and oversees pharmacovigilance activities in APAC, particularly China.

This role leads Aseptic Operations and Training for CGT, ensuring compliance, employee competency, and fostering continuous improvement across Boston-area biopharmaceutical sites.

The Principal Scientist role involves providing MSAT support for biologics manufacturing, managing timelines, troubleshooting processes, and ensuring compliance and efficiency in manufacturing operations.

The Director leads strategic CMC programs, managing planning, execution, and governance, while coaching teams and driving continuous improvement.

Lead and coordinate a portfolio of six transformation workstreams, managing program plans, cross-functional dependencies, risks, and governance. Build executive reporting, dashboards, and business cases to measure and communicate value realization. Partner with senior leaders to prioritize initiatives, secure funding, and drive timely delivery and benefits realization across global, matrixed teams.

Design and embed third‑party risk management workflows across the Source‑to‑Pay lifecycle. Define trigger‑based risk models, integrate TPRM into onboarding, contracting, and master data, enable system configurations and UAT, monitor workflow performance and KPIs, and align cross‑functional roles and controls to ensure compliant, scalable supplier risk orchestration.

Design and execute statistical infrastructure and analyses for clinical trials, observational studies, and RWD. Author SAPs, contribute to protocols and CSRs, collaborate with programming and cross-functional teams, and support dissemination of study results while seeking guidance on complex issues.

The Strategic Sourcing Director will lead sourcing initiatives, develop AI readiness programs, drive value tracking, and enhance sourcing capabilities within the organization.

As a Senior Principal AI Engineer, you will design and enhance data and AI platforms, create AI starter kits, deliver reference implementations, and advocate for cloud-first development approaches to support scalable AI adoption across Vertex Pharmaceuticals.

The Senior Accountant I will support accounting operations, manage fixed assets, ensure compliance, and optimize financial processes across multiple countries.

The Commercial Supply Chain Manager will oversee supply chain planning for a small molecule program, manage inventory, and enhance supply chain processes while collaborating across functions to ensure on-time product supply.

Provide legal advice on market access, pricing, and compliance for pharmaceutical initiatives, ensuring alignment with regulations. Collaborate with various departments and manage outside counsel.

Design, execute, and analyze in vitro mechanistic and phenotypic screening assays to support preclinical safety assessment. Leverage laboratory automation and computational tools to evaluate toxicological endpoints, investigate mechanisms of toxicity, improve translation models, present findings to cross-functional teams, mentor junior scientists, and build external collaborations to advance discovery toxicology capabilities.