Jobs at Vertex Pharmaceuticals

Lead chromatographic method development, qualification, and validation for small molecules and synthetic peptides/oligonucleotides. Design and execute complex experiments, troubleshoot instruments and methods, interpret data, ensure GMP-compliant practices, contribute to project strategy, and mentor team members.

Lead design and engineering of enterprise security platforms across network, cloud, SaaS, AI, and hybrid environments. Implement Zero Trust, firewalls, IPS, NAC, WAF, segmentation, CSPM, and telemetry. Drive secure-by-design practices, automation, platform modernization, vendor selection, and standards. Provide technical leadership, mentorship, architecture reviews, and compliance support in regulated environments.

Lead analytical method lifecycle for late-stage and commercial biologics, including remediation, validation, transfer, troubleshooting, investigations, data trending, regulatory support for INDs/BLAs, authoring technical documents, and managing vendor/CMO partnerships to ensure cGMP compliance and analytical readiness for global commercialization.

Lead marketing strategy and tactical plans for hemoglobinopathies portfolio, generate HCP and patient insights, manage agencies and communications review, measure impact of field tactics, collaborate cross-functionally, and mentor team members.

Lead and execute risk-based internal audits, oversee portions of the SOX testing program, evaluate controls and risks, develop actionable recommendations, manage audit projects and third-party audits, contribute to audit strategy and reporting, coach junior staff, and improve audit practices including data analytics and trend reporting to enhance governance and control effectiveness.

Lead the International Commercial Excellence team to design and deliver commercial programs (account planning, KPIs, incentives, go-to-market, sizing, CRM), partner cross-functionally, manage projects and budgets, and coach field teams to embed continuous improvement across international markets.

Senior individual-contributor HR leader partnering with the CDIO to lead people strategy for Data/Technology/AI. Owns talent strategy, org design, workforce planning, change leadership, leadership development, succession planning, and AI-enabled HR analytics to scale technical capability and improve organizational effectiveness across the enterprise.

Lead FP&A for the US Pain business unit: manage budgeting, forecasting, and quarterly performance reviews; provide scenario and investment analysis; influence business decisions; partner with CFO organization and drive finance process improvements.

Lead Oxford site lab technology strategy and operations: manage platform delivery, security, compliance (GxP/SOX), budget, vendor ecosystems, and a Lab Engineering Support team while acting as the primary research site partner and product-owner for demand shaping and adoption.

Serve as a strategic finance partner across COFO, leading cross-functional initiatives, SOX compliance, reporting automation, and finance transformation (system implementations, M&A). Advise on month-end close, consolidation, third-party financial risk, and FP&A impacts. Drive process improvements, analytics, and change management to support finance operations.

Lead talent acquisition strategy and execution, build proactive pipelines, partner with HR and hiring managers, source and interview candidates, advise on hiring decisions, manage recruiting initiatives and third-party search partners, and leverage AI/digital tools to enhance sourcing and hiring outcomes.

The Strategic Sourcing Director will lead sourcing initiatives, develop AI readiness programs, drive value tracking, and enhance sourcing capabilities within the organization.

The Director of Strategic Sourcing leads the development of sourcing strategies and supplier partnerships to support the company's digital and AI transformation efforts, focusing on innovation and optimizing spend.

Lead global Quality Management System strategy and governance across GxP domains, driving QMS integrity, risk management, harmonization, and continuous improvement. Oversee Quality Systems Owners, partner with enterprise functions, champion quality culture, mentor quality leaders, and lead transformation initiatives including digitization and inspection readiness.

Lead global customer master data management and governance for healthcare entity data. Manage data stewards, vendor partners, and integrations with CRM and downstream systems. Serve as data product owner, support data quality, cataloguing (Collibra), and collaborate with Data, Technology, and Engineering to deliver MDM initiatives and training.

Lead strategy, governance, and optimization of Oracle EBS financial systems supporting global finance. Partner with Accounting, Finance, IT, and auditors to deliver upgrades, integrations, controls (SOX), process improvements, and reporting. Manage vendors, projects, and a team to ensure scalable, compliant, and efficient accounting technology operations.

The Senior Paralegal provides advanced support in various Legal functions, managing workflows, investigations, and contract processes, while coordinating with attorneys and stakeholders.

The AD leads Source-to-Contract execution enablement, ensuring compliance, efficiency, and continuous improvement while managing processes and platforms for sourcing, contracting, and risk management.

Lead the US Pain HCP marketing team to develop and execute an integrated omnichannel HCP strategy for the launch of JOURNAVX. Manage agencies, drive HCP media and digital pilots, measure ROI and optimize investments, partner cross-functionally (field, patient, education), ensure compliance, and coach a high-performing team to achieve launch readiness and commercial goals.

The Senior Director will lead Global Value & Access Strategy for povetacicept, ensuring market access readiness, developing pricing strategy, and managing cross-functional teams.