Jobs at Vertex Pharmaceuticals

Lead strategic sourcing for small-molecule materials, CDMOs, and services. Develop category strategies, manage supplier relationships, oversee RFx and contracts, mitigate supply risks, drive cost savings, lead a sourcing team, and partner with stakeholders to support development, manufacturing, and commercialization.

Lead finance integration for M&A, focusing on FP&A planning, forecasting, reporting, and value-capture tracking. Partner with Finance, HR, Accounting, and stakeholders to baseline assumptions, manage governance and roadmaps, translate financials to Vertex standards, and drive transition to steady-state operations while reporting progress and risks to executives.

Lead Vertex's enterprise AI governance program: define strategy, Responsible AI framework, policies, risk management, and the AI governance platform. Partner with Legal, Privacy, Security, Quality, and business teams to ensure compliant, auditable, and scalable AI adoption across the company.

Design, develop, validate, and transfer analytical assays (ELISA, plate-based binding, cell-based bioassays, HPLC) for biologics. Independently run experiments, analyze and trend data using statistical tools, author protocols/reports, interact with vendors, and ensure methods follow ICH, USP, and EMA guidance for GMP release and stability testing.

Lead inspection readiness and compliance across internal and external GMP sites (CMOs and manufacturing/testing). Provide technical and strategic oversight of inspection management, risk-based controls, quality governance and culture, integrate new modalities, advise cross-functional teams, and manage and develop staff.

Provide strategic HR leadership for the NECAD region, translating business strategy into people priorities. Drive workforce planning, org design, talent management, performance and rewards, employee relations, and change initiatives while partnering with HR Centers of Excellence and coaching senior leaders.

Design, develop, execute and analyze analytical and release assays for cell-based products using multiple platforms (RT-qPCR, ELISA, flow cytometry, ddPCR, AlphaLISA). Troubleshoot and optimize assays, perform DOE and statistical validation, manage reagents and reference standards, author protocols/reports, transfer assays to QC, and maintain detailed documentation to support assay qualification and validation.

The Senior Automation Engineer will lead the technical vision for lab automation platforms, focusing on integration, reliability, and operational support. Responsibilities include designing and supporting automation systems, troubleshooting issues, and mentoring engineers while ensuring systems' scalability and usability.

The Associate Director of GCP Operational QA oversees clinical trial operations to ensure compliance with GCP guidelines, manages risks, and leads quality assurance activities, including audits and process improvements.

The Director of Strategic Sourcing leads the development of sourcing strategies and supplier partnerships to support the company's digital and AI transformation efforts, focusing on innovation and optimizing spend.

Lead global meetings and events strategy, manage vendor/agency performance, establish governance and scalable processes, oversee complex event logistics, ensure HCP/GDPR compliance, analyze data for process improvements, train stakeholders, and travel globally ~30-40%.

The role involves leading biomarker strategies in immunology, managing assay development and validation, mentoring teams, and communicating complex strategies to stakeholders.

The Director of Financial Planning and Analysis is responsible for overseeing financial processes, supporting budgeting, forecasting, and providing insights to enhance profitability for manufacturing operations in biotechnology.

Lead Category Management activities, including sourcing strategies, RFx development, supplier management, and market research to optimize sourcing processes.

The Senior Scientist will lead analytical method development and validation, manage external partnerships, and oversee compliance with cGMP regulations within the pharmaceutical sector.

The Principal Analyst will design and implement AI-enabled solutions for the Cell and Gene Therapy organization, collaborating with various teams to enhance operational efficiency through automation and data integration.

The Project Management Senior Manager oversees multiple departmental projects, develops integrated project plans, manages budgets, and ensures alignment with departmental goals through effective communication and stakeholder engagement.

The Heme Territory Manager will drive demand generation for Casgevy, educate healthcare providers, and build relationships within the specified territory to enhance product adoption.

The Director will lead the development of strategic market access initiatives to enhance customer engagement and optimize access across Vertex's portfolio, collaborating with cross-functional teams and managing market insights.

Responsible for market access strategy for CF products, collaborating across teams to enhance payer awareness and improve access. Manages agency submissions, develops resources for specialty pharmacies, and ensures alignment with corporate objectives through effective training and project management.