Jobs at Vertex Pharmaceuticals

Leads integrated customer experience activation strategy, translating customer journeys into digital capabilities, platform requirements, and business roadmaps. Owns website product strategy, marketing automation, customer data activation, orchestration, and agentic AI portfolios. Partners with technology and analytics teams to deliver scalable, governed, measurable engagement capabilities. Oversees vendors, leads cross-functional alignment, and manages and develops a team of 10 direct reports.

Manage the full lifecycle of complex buy-side and procurement contracts, including drafting, review, negotiation coordination, execution, renewals, amendments, and closeout. Partner with Legal, Strategic Sourcing, Finance, Privacy, Information Security, and business stakeholders to ensure compliance, manage risk, and improve contracting processes. Maintain audit-ready records, analyze contract metrics, develop procedures, support audits, and lead a small contractor team.

Provides strategic HR partnership to senior leaders across global commercial and pricing functions. Responsibilities include talent strategy, organizational design, workforce planning, succession planning, change management, commercial transformation support, leader coaching, and aligning HR programs with business priorities. The role partners with a shared People Advisor and uses data-driven insights to support organizational effectiveness and capability building.

Lead GPO account strategy and relationships for hospital GPOs to secure access for JOURNAVX. Develop and execute account plans, negotiate contracts and pricing, collaborate cross-functionally, report channel performance, and identify growth opportunities. Field-based role with ~40% travel.

Leads market access analytics, forecasting, GTN modeling, pricing and contracting analysis, and GPO performance reporting. Develops dashboards, synthesizes payer and policy impacts, and presents financial insights to senior leadership. Partners with cross-functional teams across finance, HEOR, government pricing, trade, and account management to support commercial decisions, forecasts, and future indications.

Designs and enhances an enterprise data and AI platform, building reusable AI starter kits, reference implementations, templates, and developer-focused patterns. Partners with engineering, governance, and product teams to embed governance, accelerate AI adoption, and reduce delivery time. Leads enablement programs, champions cloud-first innovation, advises cross-functional initiatives, and mentors teams developing and deploying AI solutions. Requires expertise in AI/ML, GenAI, cloud data products, Snowflake or Databricks, agile delivery, and enterprise software development.

Evaluates external pharmaceutical, biotechnology, and academic opportunities through scientific, clinical, commercial, regulatory, and financial analysis. Conducts technology and company landscape assessments, prepares decision-making materials, supports collaboration and acquisition evaluations, and coordinates cross-functional review teams and governance meetings. Builds relationships with transaction and alliance management teams, engages subject matter experts, synthesizes diverse information into recommendations, and improves insight generation and knowledge-management processes.

Leads finance strategy for Vertex’s International New Product Planning function. Partners with executive and commercial leaders on financial planning, forecasting, budgeting, performance management, business cases, scenario modeling, portfolio prioritization, pricing, market access, launch planning, and investment decisions. Ensures accurate reporting, accounting, governance, controls, and policy compliance across international markets. Drives risk and opportunity management while promoting AI and advanced analytics adoption to improve forecasting, planning efficiency, and decision-making.

Leads complex employee relations cases and workplace investigations, advises leaders and HR partners, interprets employment policies, and ensures legal and organizational compliance. The role analyzes case data and workforce trends, develops reporting and dashboards, identifies systemic risks, and recommends culture, training, and process improvements. It requires strong judgment, discretion, investigation, reporting, and executive influence skills while managing sensitive information and collaborating with Legal, Compliance, Privacy, Internal Audit, and business stakeholders.

Provides independent administrative and business support to two to three Vice Presidents. Manages complex calendars, travel and meeting logistics, confidential communications, documentation, purchase orders, invoices, contracts, visitor registration, onboarding, and executive follow-ups. Prepares meeting materials and presentations, coordinates across departments, improves administrative processes, and guides junior colleagues while maintaining strong relationships with senior leaders.

Leads enterprise talent management strategy, succession planning, talent reviews, leadership pipeline development, senior leader development, executive onboarding, and talent analytics. Advises executives and HR partners, identifies high-potential successors, designs leadership assessments and coaching programs, strengthens workforce planning, and integrates talent initiatives across HR. Partners on Workday implementations and explores AI-enabled process improvements.

Supports pharmaceutical marketing strategy by developing HCP and patient materials, managing CRM uploads, speaker programs, conferences, agency partners, budgets, and tactic performance metrics. Collaborates with brand leaders to measure impact, generate marketing insights, ensure regulatory alignment, and execute effective customer engagement initiatives. Serves as a resource for less experienced team members.

Leads financial planning and performance management for assigned functions, including budgeting, forecasting, long-range planning, variance analysis, scenario development, and risk mitigation. Partners with functional leaders and the CFO organization to identify value drivers, communicate business outcomes, improve financial processes, and influence strategic decisions. The role requires strong analytical, communication, business partnership, and continuous improvement capabilities.

Leads Vertex’s Pharmacology department and drug discovery strategy, overseeing in vitro and in vivo assay development for therapeutic potency, efficacy, and mechanism-of-action studies. Manages scientific teams, budgets, hiring, priorities, regulatory documentation, data quality, publications, and patents. Partners across functions to guide research direction, reduce risk, and advance translational models. Requires deep pharmacology and ion channel electrophysiology expertise, strong people leadership, and extensive early-stage drug discovery experience.

Lead Oxford site lab technology strategy and operations: manage platform delivery, security, compliance (GxP/SOX), budget, vendor ecosystems, and a Lab Engineering Support team while acting as the primary research site partner and product-owner for demand shaping and adoption.

Provides senior administrative and office support for department leaders, including calendar management, meeting logistics, travel booking, expense reporting, purchasing, invoices, contracts, visitor registration, onboarding, and presentation preparation. Maintains office operations, supplies, budgets, and vendor relationships while coordinating with IT and facilities teams. Supports site-wide events, handles confidential information discreetly, and serves as a resource for internal business technologies.

Leads discovery immunology programs in autoimmune and inflammatory diseases, from therapeutic target identification and validation through mechanism-of-action studies and early drug discovery. Designs and interprets in vitro, ex vivo, and in vivo research, develops disease models and translational strategies, and applies immune profiling, flow cytometry, molecular analyses, and preclinical methods. Collaborates across biology, chemistry, computational, translational, and project teams; mentors scientists; and communicates findings through publications, presentations, and strategic program updates.

Designs and develops custom optical instruments and microscopy platforms for automated drug discovery. Collaborates with biologists, chemists, physicists, engineers, and software specialists to define specifications, build prototypes, conduct proof-of-concept experiments, optimize cellular assays, and deliver production-ready imaging systems. The role requires expertise in optical design, functional cellular imaging, multiple microscopy modalities, instrument control, data analysis, and pharmaceutical research, along with mentoring and cross-functional scientific leadership.

Develops, optimizes, validates, and implements ligand binding and biomarker assays for clinical trials. Evaluates novel biomarkers in human biofluids and tissues, troubleshoots assay challenges, characterizes reagents, and supports CRO selection and assay transfers. Generates, analyzes, interprets, and presents experimental data while collaborating with research, quality, biomarker, and external teams.

Oversee outsourced nonclinical toxicology and safety studies for small- and large-molecule programs, including cell and gene therapies. Monitor CRO study conduct, data quality, protocol compliance, GLP adherence, timelines, and deliverables through on-site and remote activities. Identify and resolve study issues, prepare monitoring reports, track action items, support CRO qualification and audits, and contribute to regulatory documentation. The role also advances digital and AI-enabled approaches to improve study oversight and operational efficiency.