Scientist I, Analytical Development

Posted 3 Days Ago
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Worcester, MA, USA
In-Office
Junior
Healthtech • Pharmaceutical
The Role
Design, develop, and optimize analytical methods (HPLC, icIEF, CE-SDS, CEX) to characterize biopharmaceuticals. Independently run and troubleshoot experiments, validate methods to regulatory standards, collaborate with cross-functional teams, and mentor junior staff while ensuring GxP compliance.
Summary Generated by Built In
Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

Investigate, identify, develop, and optimize new methods and techniques to generate reliable and reproducible data in a timely manner. Read and adapt scientific literature to accomplish assignments and demonstrate broad and versatile technical expertise within discipline.

Responsibilities

  • Independently design, develop, and optimize robust analytical methods using separations-base techniques (HPLC, icIEF, CE-SDS) to characterize biopharmaceutical products
  • Implement and innovate new experimental protocols/techniques.
  • Understand the goal and maintain a high proficiency in his/her projects as well as the overall program.
  • Interpret results and draw conclusions from own multistage experiments, note significant deviations, then suggest, design, and pursue relevant experiments.
  • Understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner.
  • Perform routine and complex tasks competently and independently and generate reliable and consistent results.
  • Troubleshoot complex analytical issues and implement innovative solutions to improve method performance and efficiency.
  • Impact projects mostly through lab and/or pilot plant based activities.
  • Responsible for compliance with all applicable Corporate and Divisional policies and procedures.
  • Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.
  • Independently design and conduct critical experiments that further project goals.

Qualifications

  • Bachelor's Degree or equivalent education with 5 years of experience, or Master's degree or equivalent education with typically two years of experience. 
  • Theoretical and practical knowledge to carry out the job functions.
  • Strong understanding of protein biochemistry and analytical method development principles.
  • Experience in developing and optimizing methods for charge variant analysis, including both icIEF and CEX techniques, with the ability to transfer these methods to a QC environment.
  • Proficiency in operating and troubleshooting analytical instrumentation (e.g., Agilent, Waters HPLC systems, Maurice, PA800 systems).
  • Experience with the qualification and validation of analytical methods in accordance with ICH, FDA, and USP guidelines, ensuring methods are suitable for late-phase development and regulatory submissions.
  • Experience using automation to standardize high-throughput workflows.
  • Familiarity with statistical tools for data analysis, Empower and regulatory guidelines.
  • Experience collaborating with the process development, quality control, and regulatory affairs teams to align analytical strategies with project timelines and goals.
  • Capable of providing technical guidance and mentorship to junior scientists and laboratory staff.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors  including  geographic location, and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. ​

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

  • This job is eligible to  participate in our short-term incentive programs. ​

Note: No amount of pay is  considered to be wages or compensation until such amount isearned,  vested,  and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a   particular employee  remains in the Company's sole and absolute discretion unless and until paid and may be  modified at the Company’s sole and absolutediscretion,  consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Skills Required

  • Bachelor's degree with 5 years' experience or Master's degree with typically 2 years' experience
  • Strong understanding of protein biochemistry and analytical method development principles
  • Experience developing and optimizing charge variant analysis (icIEF and CEX) and transferring methods to QC
  • Proficiency operating and troubleshooting analytical instruments (Agilent, Waters HPLC systems, Maurice, PA800)
  • Experience with qualification and validation of analytical methods per ICH, FDA, and USP guidelines
  • Experience using automation to standardize high-throughput workflows
  • Familiarity with statistical tools for data analysis and Empower software
  • Experience collaborating with process development, quality control, and regulatory affairs teams
  • Ability to design, interpret, and troubleshoot multistage experiments independently
  • Capable of providing technical guidance and mentorship to junior scientists and laboratory staff

AbbVie Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AbbVie and has not been reviewed or approved by AbbVie.

  • Retirement Support 401(k) contributions include a dollar-for-dollar match up to 6% plus an additional annual company contribution tied to age and service. Company-paid life insurance and other financial protections further strengthen long-term security.
  • Parental & Family Support Paid leave programs include up to 12 weeks at 100% for parental leave and separate paid caregiver leave, with eligibility after six months where noted. Adoption and surrogacy reimbursements and family-building resources add further support.
  • Healthcare Strength Health coverage begins on day one with medical, dental, vision, mental health, and prescription benefits, and preventive care covered at 100%. Options such as HSAs/FSAs and coverage for spouses/domestic partners and children up to age 26 broaden accessibility.

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The Company
HQ: Chicago, IL
50,000 Employees
Year Founded: 2013

What We Do

AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.

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