Scientist, Bioanalytical LC-MS

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do:

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)

About the Role:Supports multiple functions related to Bioanalytical discovery and development. Responsible for at least one following bioanalytical activities (instrumental analysis (LC/MS/MS and/or LC/UV or ligand binding assays/immunogenicity assays), automation, matrix analysis, specialty mass spectrometry techniques, method development/validation, GLP studies, biomarker analysis, enzyme- or immuno-based assays). May be a primary point of contact for certain bioanalytical efforts.

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Your Contributions (include, but are not limited to):

• Perform sample analysis to support bioanalysis efforts for preclinical studies, including pharmacokinetics, pharmacodynamics, immunogenicity, and biological activity

• Generate and characterize critical reagents to support assay development and assay life cycle maintenance (e.g., Biotinylation)

• Effectively communicate results to internal/external teams in presentations and internally authored reports

• Prepare documents to support technical transfer of methods to CROs

• Maintain a safe, organized, and operational laboratory space including maintenance of equipment and procurement of supplies

• May perform pharmacokinetic assay method development, including ligand binding assays/immunogenicity assays

• May perform other techniques such as western blotting, genomic isolations, RT-qPCR, and ddPCR

• Peer QC lab notebooks, study reports, and regulatory contribution BA sections

• Performs other duties as assigned

Requirements:

• BS/BA degree in biology, chemistry, or related science and 2+ years of industry experience in an biotech, pharma, and/or CRO setting; Experience working in and accomplishing tasks a timeline driven setting; Experience in lab automation is preferred; Experience in large molecules and biomarkers bioanalysis is beneficial OR

• MS/MA degree in biology, chemistry, or related science and some industry experience preferred OR

• PhD or equivalent and some experience

• Some background in bioanalytical job-relevant core competency (instrumental analysis (LC/MS/MS and/or LC/UV), automation, matrix analysis, specialty mass spectrometry techniques, method development/validation GLP studies, biomarker analysis) or Some background in bioanalytical job-relevant core competency (immunoassays such as ELISA, handling of a variety of biological matrices such as serum and plasma, automation, method development/validation GLP studies, biomarker analysis)

• Some hands-on experience with role-appropriate technology and methodology such as: automation, LC-MS/MS, radioisotope use, PK analysis and modeling and simulation software

• Developing strong written and verbal communication skills

• Detail oriented yet developing the ability to see broader picture of scientific impact on team

• Developing understanding of project / group goals and methods

• Developing the ability to recognize anomalous and inconsistent results and interprets experimental outcomes

• Developing knowledge of one or more scientific disciplines, becoming expert in one discipline

• Developing strong knowledge of scientific principles, methods and techniques

• Ability to work with a variety of laboratory instrumentation and/or PK analysis and or modeling and simulation software

• Excellent computer skills

• Developing problem-solving, analytical thinking skills

• Ability to meet multiple deadlines, with a high degree of accuracy and efficiency

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Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

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The annual base salary we reasonably expect to pay is $89,800.00-$123,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.