Responsibilities will include:
- Preparing DNA and RNA sequencing libraries using established and novel chemistries.
- Developing, optimising and troubleshooting molecular biology protocols, including nanopore sequencing workflows.
- Planning and independently delivering research projects from experimental design through to data generation and evaluation within an agile research environment.
- Performing preliminary data analysis and visualisation using appropriate bioinformatics tools.
- Maintaining clear experimental records and producing high-quality protocols, technical reports and project updates.
- Collaborating effectively with multiple teams across Oxford Nanopore.
- Providing technical guidance and mentorship to junior colleagues and interns.
- Staying up to date with developments in sequencing technology, molecular biology and RNA research.
What We’re Looking For...
Essential skills and experience:
- PhD , or equivalent research experience, in RNA biology, molecular biology, biochemistry, chemical biology or a related discipline.
- Proven background in RNA molecular biology, including RNA purification, enzymatic manipulation and integrity assessment.
- Strong understanding of RNA stability, degradation, secondary structure and enzymology.
- Demonstrated ability to independently design, optimise and troubleshoot complex experiments.
- Familiarity or willingness to develop proficiency in Python, Bash or command-line bioinformatics tools.
Desirable skills and experience:
- Experience with long-read transcriptomics, ideally Oxford Nanopore direct-RNA sequencing.
- Experience working with synthetic, chemically modified or therapeutic RNA molecules, including an understanding of RNA modification and end chemistry.
- Experience developing RNA manipulation, capture or library-preparation methods, and/or studying RNA structure or interactions.
- Familiarity with computational tools for bioinformatics analyses and data visualization.
- Knowledge of functional genomics, including nucleotide modifications and genome regulation.
Oxford Nanopore Technologies: Our goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology for faster, information rich, accessible and affordable molecular analysis. The first application is DNA/RNA sequencing, and the technology is in development for the analysis of other types of molecules including proteins. The technology is used to understand and characterise the biology of humans and diseases such as cancer, plants, animals, bacteria, viruses, and whole environments. With a thriving culture of ambition and strong innovation goals, Oxford Nanopore is a UK headquartered company with global operations and customers in more than 125 countries.
Skills Required
- PhD or equivalent research experience in RNA biology, molecular biology, biochemistry, chemical biology, or a related discipline
- Proven experience in RNA molecular biology, including RNA purification, enzymatic manipulation, and integrity assessment
- Strong understanding of RNA stability, degradation, secondary structure, and enzymology
- Ability to independently design, optimise, and troubleshoot complex experiments
- Familiarity with or willingness to develop proficiency in Python, Bash, or command-line bioinformatics tools
- Experience with long-read transcriptomics, ideally Oxford Nanopore direct-RNA sequencing
- Experience with synthetic, chemically modified, or therapeutic RNA molecules, including RNA modification and end chemistry
- Experience developing RNA manipulation, capture, or library-preparation methods, or studying RNA structure or interactions
- Familiarity with computational tools for bioinformatics analysis and data visualisation
- Knowledge of functional genomics, nucleotide modifications, and genome regulation
Oxford Nanopore Technologies Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Oxford Nanopore Technologies and has not been reviewed or approved by Oxford Nanopore Technologies.
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Fair & Transparent Compensation — Pay is considered good to above average across many roles, with employer-provided ranges visible for several U.S. commercial and applications positions and company materials emphasizing market‑competitive base pay. Commercial and some senior technical posts, particularly in the U.S., are positioned as competitive and often paired with strong variable components.
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Equity Value & Accessibility — All‑employee share plans in the UK and a U.S. employee stock purchase plan indicate broad access to equity as part of total reward. Company communications highlight attractive bonus and share plans that add meaningful upside beyond base pay.
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Healthcare Strength — U.S. roles indicate strong health insurance and core protections, while official materials and country overviews reference private medical coverage and wellbeing support. These elements position the health package as a notable strength alongside cash compensation.
Oxford Nanopore Technologies Insights
What We Do
Our goal is to enable the analysis of anything, anywhere, by anyone. We have developed the world’s first and only nanopore DNA and RNA sequencing platform. It’s a new generation of sequencing technology — the only one to offer: scalability to portable or ultra-high throughput formats, real-time data delivery, and the ability to elucidate rich biological data. We are aiming to disrupt the way that biological analyses are currently performed, and open up new applications that have a profound, positive impact on society. Our devices offer real-time analysis, for rapid insights, in fully scalable formats — from pocket to population scale — and the technology is being used in more than 100 countries worldwide. Founded in 2005 as a spin-out from the University of Oxford, the company now employs more than 600 people from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.
