Program Manager, Platform & Operations

At Orakl Oncology, we are accelerating the development of oncology treatments. Today, fewer than 5% of new cancer drugs succeed in clinical trials. Clearly, new methods are needed. We combine cutting-edge biology and AI to build the next generation of insight platforms, powered by the world's largest cohort of patient tumor avatars. These avatars fuel our AI-powered predictive engine, helping to anticipate clinical trial outcomes, validate therapies, and uncover new drug candidates. By generating multimodal, real-world data, we deliver insights that consistently outperform existing solutions.

Our mission is simple yet ambitious: to bring more effective treatments to patients who need them, and to make drug development smarter, faster, and more personalized. We collaborate with top hospitals, research institutes, and pharmaceutical companies worldwide. Backed by leading investors, we are a fast-growing, mission-driven startup at the intersection of science and technology.

We are looking for a Senior Technical Program Manager to ensure Orakl's scientific platform operate as one system. Our platform spans severals functions (biobank, R&D, data science, computational biology, and pharma and hospital partnerships), and each one depends on the others to deliver. Your job is to make they work as pillars for the company: aligned on shared goals, coordinated on dependencies, and measured in a way that reflects both the science and the business.

This is a senior, high-ownership role inside Platform and Operations. You will act as a strategic thought partner to the science leads, build and track the program view of the whole platform, keep everyone working from the same roadmap and the same numbers, anticipate where things will break before they do, and make sure our biobank, our external partners, and our internal research all pull in the same direction. You will also help embed a product mindset across the platform and steward our emerging product department, turning strong science and recurring partner demand into clearly scoped, owned products. You will report to the Head of Platform Strategy and Operations, and work daily with the team leads, BD, and the Alliance Manager who owns partner delivery.

1. Run the cross-functional roadmap

• Own the cross-functional work breakdown across biobank, data, computational biology and partnerships: owners, priorities, timelines, interdependencies

• Translate scientific ambitions into executable plans with clear milestones and costs, support each team in building their roadmap and capacity

• Coordinate technical and scientific roadmap execution, identify opportunities and risks, drive remediation, shape priorities with teams

2. Drive operational excellence

• Build and run the KPI framework with the Chief of Staff so each pillar's technical metrics roll up into business and strategic KPIs

• Keep one source of truth for roadmap, KPIs, dependencies and status across Notion, Asana and SharePoint

• Spot optimization possibilities and drive technical scaling

3. Support platform portfolio management

• Support the execution of our virtual patients collection strategy, taking into account scientific and clinical capabilities as well as R&D and business needs

• Contribute to grant writing and manage subsequent collaborative work

• Coordinate and help arbitrate resource allocation to align them with company goals, supporting both internal development and business execution needs

• Coordinate the definition and scoping of R&D bricks supporting the development of our current and future products, aligning Product and R&D teams

• Min 5-7 years experience, including at least 3 years in program or portfolio management in an industrial, tech or biotech environment

• An advanced degree (MSc or PhD) in a life sciences, computational biology, computer science or related field

• Understanding of drug discovery and development, ideally in the field of oncology

• Experience building KPIs or OKR reporting

• Exposure to product management or product operations, ideally in a scientific or technical setting

• Comfortable in fast paced environments, navigating ambiguity and adapting plans as things change, without losing the thread and focus

• Genuine curiosity for both data/AI and biology worlds: you enjoy talking metrics and delivery with wet and dry scientists and engineers

• Excellent communication and stakeholder skills across all levels of the organisation, up to founder level

• Fluency with the tools we use (or similar ones) to run this: Notion, Asana, SharePoint, and dash-boarding

• Fluent in English

• Formal project management certification

• Experience in tech, biotech, a CRO or a data-heavy R&D organisation

• Scientific understanding in tumor biology, target discovery or 3D cell models

• Familiarity with biobank or lab operations, and with data and omics pipelines (teams working in GitHub and AWS). You do not need to code, but you should understand how the work flows.

• Experience managing external vendors, consortia, or grant-funded programs

• Experience setting up PMO structure, cadence, and reporting automation from scratch

• French is a plus (the team is based in Paris)

• We all win when the team moves together, not is silos

• We build our capabilities as products, with owners and a clear reason to exist: clinical impact

• We would rather plan around a bottleneck three months out than firefight it, so raising risk early is expected and welcome

• We want you to build, challenge, and follow metrics that reflect reality and drive decisions, not decorating slides

• We have a feedback culture based on authentic and honest communication, where challenge and pushback are welcomed

Orakl Oncology is a dynamic, flexible, passionate and highly interdisciplinary team. If you want to interact with stellar clinicians, biologists and engineers on a day-to-day basis to transform oncology research, this is the place for you!

You will find:

• Mission: Work in a cutting-edge environment, on the cutting-edge of cancer research.

• Growth opportunities: we’re rapidly expanding the scope of our work and you will be offered multiple opportunities to grow with it!

• Impact: you’re going to be participating in a fast-growing, multi-faceted project with multiple opportunities to shape it according to your interests.