Who Are We?
Our company is based on the science of our founder, Stanley Qi, one of the original CRISPR co-inventors who then furthered the technology so that DNA does not need to be cut to accomplish gene regulation. Instead, we regulate the epigenome to suppress and activate multiple genes simultaneously. We are further evolving the platform and leveraging its strengths to address unmet medical needs.
We are looking for exceptional team members who want an active role in building a rapidly growing biotech.
Title: Scientist I/ Scientist II, Bioanalytical
Location: South San Francisco, CA
Opportunity:
Epicrispr Biotechnologies is seeking a motivated Scientist I / Scientist II, Bioanalytical to support the development and execution of bioanalytical strategies across our pipeline. This individual will contribute to advancing preclinical and clinical programs through hands-on assay development, biomarker analysis, and data generation. The ideal candidate is detail-oriented, collaborative, and excited to grow in a fast-paced biotech environment.
Roles and Responsibilities:
- Design, develop, and execute bioanalytical assays to support preclinical and clinical studies, including PK/PD and biomarker assessments
- Perform routine and complex experiments, analyze data, and clearly document results
- Support development of cell-based potency assays for early-stage and clinical programs
- Troubleshoot assays and optimize methods to improve performance and reproducibility
- Maintain accurate and organized laboratory records and ensure data integrity
- Collaborate with cross-functional teams including R&D, Clinical Development, and Translational Sciences
- Coordinate with external CROs for sample analysis and timelines as needed
- Contribute to regulatory documentation by supporting bioanalytical sections of INDs and other filings
- Stay current with relevant technologies and apply new methods where appropriate
- Present findings in team meetings and contribute to scientific discussions
- Ensure compliance with GLP/GCP standards and internal quality systems
Qualifications:
• Scientist I:
- Ph.D. in Biology, Pharmacology, Bioanalytical Chemistry, or related field,
or - Master’s with 0–3+ years of relevant industry experience
• Scientist II:
- Ph.D. with 2–5 years of relevant industry experience,
or - Master’s with 4–7 years of relevant industry experience
Skills:
- Hands-on experience with bioanalytical assay development and/or execution
- Familiarity with techniques such as qPCR, digital PCR, ligand binding assays, LC-MS/MS, flow cytometry, and/or reporter gene assays
- Experience supporting gene therapy, cell therapy, or nucleic acid-based therapeutics is a plus
- Basic understanding of PK/PD principles and translational science
- Strong attention to detail and problem-solving skills
- Ability to work both independently and collaboratively in a team environment
- Effective communication and organizational skills
- Comfortable working in a fast-paced, evolving environment
Compensation: The salary range for this position is $124,000 to $148,000 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.
Epicrispr Biotechnologies is an early-stage biotechnology company developing a novel technology platform that can provide safe and persistent control of targeted gene regulation. Our proprietary platform represents an entirely new class of therapeutics that can be leveraged to treat severe disease across numerous therapeutic areas, including complex diseases impacted by multiple genes.
Epicrispr Biotechnologies provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.
Skills Required
- Ph.D. in Biology, Pharmacology, Bioanalytical Chemistry, or related field
- 8+ years of relevant industry experience or Master's with 12+ years
- Expertise in bioanalytical, biomarker analysis, and potency assays
- Understanding of PK/PD principles and translational science
- Experience managing CROs and external partners
- Familiarity with regulatory requirements (FDA, EMA)
- Excellent communication and leadership skills
What We Do
Epicrispr Biotechnologies is a biotechnology company developing ultracompact therapies to modulate gene expression in vivo using the smallest known Cas protein, CasMINI
