About the Role
As a protein analytics scientist you will be a crucial member of our interdisciplinary team, comprising highly creative and talented individuals, with exceptional expertise in analytical characterization of therapeutic biologics candidates for development. This role is critical for hit generation, lead optimization, and identification of development candidates. The ideal candidate will have a background in mass spectrometry, BLI, cIEF, HPLC (HIC, SEC, etc.), and other analytical techniques with experience in employing automated methods for sample generation and data analysis in the pharmaceutical/biotech industry.
About You
You are an enthusiastic scientist who takes pride in developing analytical methods for protein characterization using automation where appropriate. You are highly proficient in multiple analytical techniques employed for biologics discovery, multi-parameter optimization and development with hands-on experience in preclinical and CMC activities involving complex biologics. You are an experienced manager who has led technical teams responsible for biologics characterization.
Key Responsibilities
- Working with hit and lead teams to characterize biologics using a diversity of methods including but not limited to mass spectrometry, BLI, cIEF, HPLC, etc.
- High throughput developability assay development for multi-parameter optimization of biologics.
- Establish assays to triage leads based on biophysical and molecular attributes of traditional and complex biologics.
- Establish automated sample preparation and data analysis pipelines where appropriate.
- Design and implement data communication protocols and implement best practices.
- Train and mentor junior team members, providing guidance on experimental design, data analysis, and troubleshooting.
- Maintain accurate and detailed records of experiments, protocols, and results in accordance with company standards and assist in CMC assay transfer as needed.
- Interpret and present scientific findings at research meetings. Provide scientific input and propose follow-up experiments.
- Collaborate and communicate across diverse research teams to successfully achieve scientific goals.
- Contribute to scientific publications, patents, and presentations to disseminate research findings both internally and externally.
Qualifications
- Ph.D. in Chemistry or Analytical Chemistry or related field with 5+ years of industry experience related to analytical characterization of biologics.
- Experience in setting up assays and protocols to analyze biologics samples for discovery and development.
- Experience in CMC analytical method development, technology transfer, and QC attributes is highly desirable.
- Excellent analytical and problem-solving skills, with meticulous attention to detail.
- Strong written and verbal communication skills, with the ability to effectively present complex scientific concepts to both technical and non-technical audiences.
- Ability to work effectively in a collaborative, multidisciplinary team environment, fostering cooperation and knowledge-sharing among team members.
- Demonstrated ability to mentor junior research associates.
- Experience with protein production and high-throughput screening workflows.
- Experience using LIMS and Benchling systems.
Compensation
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. The base pay range for this position is expected to be $150,000 - $205,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.
Top Skills
What We Do
Xaira Therapeutics is an integrated biotechnology company driving advances in artificial intelligence to learn the language of life and transform how we treat disease. The company seeks to rethink the drug discovery and development process from end-to-end by bringing together leading talent across three core areas: machine learning research to better understand biology, expansive data generation to power new models, and robust therapeutic product development to treat disease. Xaira is headquartered in the San Francisco Bay Area
