Principal Quantitative Scientist (m/f/d)

Reposted 17 Hours Ago
Be an Early Applicant
3 Locations
In-Office
4K-4K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
The Role
As a Principal Quantitative Scientist, you'll lead real-world data studies, influencing regulatory decisions and collaborating with cross-functional teams to enhance digital health solutions.
Summary Generated by Built In

Let’s build a healthier future, together! By combining our unique strengths, we are redefining healthcare through sustainable action and innovation. For a behind-the-scenes look, check out this video to see how we at Roche are making personalized health care a reality. 


The mySugr GmbH was acquired by Roche in 2017 and our Vienna office is one of Roche's global sites. You will be located here, in the heart of Vienna, no matter if you work on a mySugr®, Accu-Chek®, navify® or any other Roche product or solution. You can read more about the history of mySugr & Roche here.

Here's what we're looking for:

Roche Diagnostics has built a new strategic area – Roche Information Solutions (RIS) - charged with creating a modern portfolio of decision support software products and generating insights that change the way patients are cared for. Our challenge is to bring together complex diagnostic and treatment data from medical devices and IT systems and intelligently process and present this data to clinicians, researchers, and caregivers to improve research outcomes and patient care by offering a suite of Clinical Decision Support (CDS) solutions. We also work with clinical care solutions that are tailored to be used by the patient directly and empower them with the tools to manage their health. 

As a Principal Quantitative Scientist, you will act as a scientific leader for Real-World Data (RWD), driving evidence generation that fundamentally shapes the development and adoption of our digital health, IVD, and medical device products. This is a high-impact, independent role requiring deep expertise and the ability to influence critical business and regulatory decisions. Your work will involve strategically shaping analyses involving diverse data types (including EHR, claims, omics, and digital health data) in close alignment with data scientists and biostatisticians.

Your upcoming mission:

RWD Strategy & Execution (End-to-End Leadership):

  • Drive the conceptualization, planning, execution, and reporting of advanced RWD studies using various research and commercial healthcare databases.

  • Develop rigorous RWD study protocols and lead complex analyses to support the evidence needs of the IVD, medical device, and digital health portfolio.

  • Ensure the design, execution, and presentation of RWE adhere to the highest scientific and methodological standards.

Strategic Influence & Adoption

  • Act as a RWD leader, working closely with cross-functional stakeholders such as Product Leads, Medical Affairs, and Clinical Development to ensure RWD projects directly support commercial, market access, and regulatory needs.

  • Champion RWD's use to supplement clinical evidence and actively identify opportunities where RWD can serve as the primary evidence mechanism to achieve regulatory and reimbursement objectives.

  • Collaborate with external partners (KOLs, academic institutions, healthcare authorities) on study design and foster strong relationships to explore new data assets and analytical methodologies

Expertise & Mentorship:

  • Leverage and expand expertise in RWD sources, epidemiology, and state-of-the-art causal inference methodologies.

  • Promote innovation by enhancing ways of working (processes, methods, technology) and proactively sharing learnings with peers.

  • Mentor junior colleagues and act as an influential subject matter expert to the team.

Essential Skills for your mission:

  • You hold a PhD (preferred) OR Master’s Degree in a Quantitative science field (e.g. Pharmacoepidemiology, Epidemiology, RWD Biostatistics, Pharmacoeconomics, Health Economic and Outcomes Research)

  • And 7+ years of directly related (industry, consulting, or other relevant) experience.

  • Proven track record of utilizing RWD to support regulatory submissions.

  • Solid expertise in epidemiology and causal inference methodologies is required.

  • Strong experience in using diverse RWD sources to generate insights and evidence.

  • Experience in the Cardiovascular, Renal, and Metabolic (CVRM) therapeutic area is highly preferred.

Bonus Skills:

  • Expertise in RWD & Epidemiology: Proven hands-on experience in designing, implementing, and reporting RWD studies, with specific expertise in epidemiology and a passion for making a difference in healthcare.

  • Analytics: Programming experience with R, Python, SQL and/or other quantitative software.

  • Strategic & Regulatory Acumen: A solid understanding of regulatory guidelines and an ability to use RWD to influence national and international reimbursement and clinical guidelines.

  • Project & People Leadership: Strong project management skills, including the ability to manage scope and delegate. You are a recognized team leader with experience mentoring team members and possess a resilient, can-do attitude.

  • Communication & Collaboration: Excellent communication and collaboration skills, including the ability to influence others without formal authority. A professional working proficiency in English is required.

  • Problem-Solving & Mindset: A data-savvy, creative, and resilient problem solver with a sense of ownership and attention to detail. You are eager to learn and expand your scientific expertise as a reliable team player and thought partner.

What to expect:

  • Ambitious and passionate people building meaningful products for a global audience

  • An innovative agile working environment allowing for collaboration with really smart people and knowledge sharing in cross-functional teams 

  • Loads of benefits ( Apple hardware, fitness, public transport, lunch benefit, language classes, professional training budget, chance to join global conferences...)

  • Flexible working hours and home office policy, 5 weeks vacation

  • An amazing office with a rooftop terrace, fully stocked kitchen and amazing barista coffee machines in the middle of Vienna… oh, and did we mention the best team in the world!

In Austria, we have a legal obligation to disclose the minimum salary according to our collective agreement, which is gross EUR 3.843  - per month for this position. But! Rest assured, we offer amazing competitive compensation packages which take into consideration current market trends, therefore you can expect a higher offer that reflects your experience level.

Who we are and what we care about?

We are committed to providing a healthy, equal and inclusive working environment for our employees to bring true relief to the patient! We care about family friendly career paths, sustainability, a healthy lifestyle and the flexibility of a modern workplace. We maintain a culture of learning and sharing, as well as open and candid feedback. At every level, there are many opportunities to develop and grow - both professionally and personally. 

As a healthcare pioneer committed to transforming the lives of billions of people around the globe, we push boundaries to redefine what is possible. We know that early, accurate diagnosis is essential to maintain health, prevent disease and help advance new, targeted treatments and potential cures for the world’s most serious health problems. We have a passion for innovation and a profound commitment to make a lasting impact on society by continuing to improve the standard of care for humankind. Our culture inspires us to create healthcare that is sustainable, efficient and financially viable. Healthcare that is built on people’s needs, strong data and clinical insights. Healthcare that saves lives.

Interested? Great. We’d like to hear from you! Just click that “Apply Now” button and send us your CV in English …. and anything else that you think might impress us.

Roche is an Equal Opportunity Employer.

Skills Required

  • PhD or Master's Degree in a Quantitative science field
  • 7+ years of related experience
  • Track record utilizing RWD for regulatory submissions
  • Expertise in epidemiology and causal inference methodologies

Roche Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Roche and has not been reviewed or approved by Roche.

  • Retirement Support U.S. materials describe a 401(k) with both matching and an additional company contribution, supported by formal plan documents and true‑up features. This structure is positioned as a standout element of the total package, particularly at Genentech.
  • Leave & Time Off Breadth Time‑off provisions include substantial vacation, a year‑end shutdown, and a paid six‑week sabbatical after six years. These elements indicate a recharge‑oriented approach within the U.S. offering.
  • Healthcare Strength Company materials emphasize comprehensive medical, dental, vision, and mental‑health resources alongside well‑being programs. Benefits pages consistently highlight breadth across core health coverage elements.

Roche Insights

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The Company
Provincia de Buenos Aires
93,797 Employees
Year Founded: 1896

What We Do

Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare – a strategy that aims to fit the right treatment to each patient in the best way possible. Roche is the world’s largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. Thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Roche has been recognised as the Group Leader in sustainability within the Pharmaceuticals, Biotechnology & Life Sciences Industry ten years in a row by the Dow Jones Sustainability Indices (DJSI).

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