Who Are We?
Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by uniting patients, care teams, and researchers on a secure, technology-enabled platform that drives clinical innovation and offers a path towards better patient outcomes.
This is precision cardiology, and we know it’s within reach.
What Will You Do?
The Overview
The Principal Product Designer to own the end-to-end design of our products — from early-stage discovery through polished, production-ready interfaces. This is a foundational hire at a critical stage of growth. You will be the design voice in the room: following standards, collaborating with Product & Engineering, and delivering work that meets both the needs of clinicians and patients.
This individual contributor role is ideal for a seasoned generalist who is comfortable with ambiguity and confident in using their craft to create clarity. A strong candidate will be equally skilled in gathering requirements, building information architecture, and crafting high-fidelity UI.
The Specifics
- Define and drive long-term product vision and design strategy for multiple products. Lead complex, ambiguous design problems from conceptual exploration through detailed execution.
- Partner with Product Manager and Engineering teams to conduct workshops, feature definition, and stakeholder management
- Collaborate with clinical, regulatory, and legal teams to translate user needs into design artifacts and specifications
- Design high-fidelity mockups and interactive prototypes for user research and development handoff
- Update organization regularly on product design progress.
- Represent the design perspective for broad, non-technical audience
Why Prolaio?
- Impactful Work: You will join in the fight against heart failure (HF) and hypertrophic cardiomyopathy (HCM) with the goal of extending and saving the lives of our patients while also being at the forefront of changing the healthcare industry through technology.
- Innovative Environment: You will be part of an organization doing something that’s never been done before.
- Professional Growth: You will join a growing team and have a substantial impact on our daily and future operations with the opportunity to continuously learn and grow.
- Collaborative Team: You will be part of a team of collaborative, curious, and committed individuals focused on the collective good, inclusiveness, scientific excellence, and advancing digital health for cardiology.
Who You Are?
- 7+ years of product or UX/UI design experience, including 3 years in a senior or principal-level role
- Portfolio demonstrating end-to-end of complex product design, ranging from long term product vision, to detailed execution
- Hands-on experience designing for regulated industries, preferably medical devices, health IT, or clinical software
- Strong organization, written, and verbal communication skills, including ability to document design rationale and detailed specifications.
- Working understanding of product management and development processes, with demonstrated experience collaborating with those disciplines
Why You’ll Love Working Here
- Meaningful Compensation: Competitive salary, performance bonus, and equity so you can share in what we build.
- Great Health Coverage: Medical, dental, and vision plans with multiple options and strong company contributions.
- Flexible Spending Perks: HSA, FSA, commuter benefits, and a $1,200 annual Lifestyle Spending Account to support wellness, commuting, family needs, and more.
- Time to Recharge: Generous paid time off, sick leave, and company holidays.
- Family-First Benefits: Paid parental leave, caregiver leave, and support for growing families.
- Security & Peace of Mind: Company-paid life insurance and short- and long-term disability coverage.
- Plan for the Future: 401(k) plan to help you build long-term financial security.
- Care When You Need It: Easy access to telehealth and optional supplemental coverage for life’s unexpected moments.
Starting Salary is at $154,000.00 (Exact Compensation may vary based on skills, experience, and location)
Skills Required
- 7+ years of product or UX/UI design experience
- At least 3 years in a senior or principal-level design role
- Portfolio demonstrating end-to-end complex product design from vision to detailed execution
- Hands-on experience designing for regulated industries (medical devices, health IT, or clinical software)
- Ability to design high-fidelity mockups and interactive prototypes for research and development handoff
- Strong written and verbal communication skills, including documenting design rationale and detailed specifications
- Working understanding of product management and development processes with demonstrated cross-functional collaboration
Prolaio Compensation & Benefits Highlights
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Healthcare Strength — Health, dental, and vision coverage start on day one, with the company paying roughly 80–90% of premiums depending on plan and coverage level. Employer-paid short- and long-term disability and basic life insurance are also called out in public listings.
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Leave & Time Off Breadth — New hires are listed with 15 vacation days accruing immediately, 10 sick days, and 13 paid company holidays. Several sources also mention additional personal or wellness days that broaden paid time away options.
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Wellbeing & Lifestyle Benefits — A Lifestyle Spending Account via Benepass provides about $100 per month ($1,200 annually) for wellness, commuting, and similar expenses. Commuter benefits, wellness programs, and access to an onsite gym are also referenced in recent postings.
Prolaio Insights
What We Do
Prolaio is a clinical intelligence company dedicated to unlocking continuous, predictive and shareable heart data to liberate patients from hospital-based reactive care and accelerate every new therapy. The company was created by cardiologists, cardiovascular practitioners, and data scientists specifically to address the world’s number one cause of death — cardiovascular disease. By combining scientific rigor with cutting‑edge technology, Prolaio aims to transform real‑world heart data into faster discovery today and precision care for functional cures tomorrow.
Why Work With Us
Kardigan and Prolaio were both founded to challenge the status quo in cardiology. If we have any shot at radically reducing the time and cost to develop meaningful new medicines and provide better healthcare access and outcomes for patients, we need to fundamentally embrace real-world data and AI-based tools in a way that is fully integrated across
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Prolaio Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
