Principal Architect, AI-Native Applications

Posted Yesterday
Be an Early Applicant
Newark, NJ, USA
In-Office
150K-200K Annually
Senior level
Healthtech
The Role
Leads organization-wide architecture for AI-native applications, defining standards and reference implementations for backend systems, data platforms, APIs, microservices, LLM integrations, retrieval-augmented generation, and agentic workflows. Designs scalable cloud and on-premises architectures, ensures healthcare security and compliance, conducts architecture reviews, partners with technical and business leaders, and mentors senior engineers while remaining hands-on in code.
Summary Generated by Built In

WebMD Ignite, a division of WebMD and Internet Brands, is the growth partner for healthcare organizations. We guide people to better health at all stages of their journey, from discovery to recovery. Our combination of leading brands in the industry—including WebMD, Medscape, Krames, PulsePoint, Vitals, The Wellness Network, Mercury Healthcare, and Healthwise—offers comprehensive solutions that engage individuals with timely, relevant messaging that optimizes experiences and outcomes, driving loyalty and lifetime value for our clients. Learn more at WebMDIgnite.com.

WebMD Ignite, a division of WebMD and Internet Brands, is the growth partner for healthcare organizations. We guide people to better health at all stages of their journey, from discovery to recovery. Our combination of leading brands in the industry — including WebMD, Medscape, Krames, PulsePoint, Vitals, The Wellness Network, Mercury Healthcare, and Healthwise — offers comprehensive solutions that engage individuals with timely, relevant messaging that optimizes experiences and outcomes, driving loyalty and lifetime value for our clients. Learn more at WebMDIgnite.com.

About the Role:

The Principal Architect, AI-Native Applications is the lead technical authority for how WebMD Ignite designs, builds, and scales modern applications in an AI-native environment. This role defines the architectural patterns, standards, and reference implementations that development teams across the organization build against, with a particular focus on backend systems, data-intensive services, and applications that embed large language models, retrieval-augmented generation, and agentic workflows. The Principal Architect operates as a hands-on individual contributor and technical leader, remaining close enough to the code to pair with senior engineers and validate design decisions directly. This is a senior, cross-cutting role that establishes a coherent application architecture practice where design decisions are currently made project by project.

Key Responsibilities:
  • Define and own the application architecture patterns, standards, and reference implementations that development teams build against across the organization.

  • Architect complex backend systems, including microservices architectures, APIs, streaming and event-driven protocols, and data engineering pipelines.

  • Design high-performance data platforms for AI workloads, including vector stores, graph databases, distributed caching, and semantic retrieval over million-record corpora.

  • Establish the patterns and guardrails for AI-native applications, including LLM integration, retrieval-augmented generation, multi-model orchestration, and agentic workflows.

  • Conduct architecture reviews and ensure solution designs meet scalability, performance, security, interoperability, and cost requirements across both cloud and on-premises environments.

  • Set standards for AI-ready APIs, data services, and application frameworks that enable rapid prototyping and production rollout of new capabilities.

  • Partner with engineering, product, data, and DevOps leaders to align technical direction with business outcomes and delivery timelines.

  • Ensure architectures meet the security, compliance, and privacy requirements of regulated healthcare environments, including HIPAA and the handling of protected health information (PHI). 

  • Provide technical mentorship to senior engineers and raise the overall architecture fluency of the engineering organization. 

Qualifications:
  • 7+ years of experience in software architecture, backend engineering, or data engineering, including senior or principal-level technical leadership. 

  • Demonstrated experience architecting complex, distributed backend systems using microservices, APIs, and event-driven or streaming patterns.

  • Hands-on experience designing and operating data platforms for high-volume, high-dimensional workloads, including vector databases, graph databases, distributed caching, and semantic retrieval.

  • Practical experience building AI-native or AI-enabled applications, including LLM integration, retrieval-augmented generation, orchestration frameworks, and agentic systems.

  • Strong command of cloud architecture (AWS, Azure, or GCP) and experience operating across both cloud and on-premises environments. 

  • Ability to remain hands-on in code while providing architecture-level leadership.

  • Working knowledge of the security, privacy, and compliance requirements of healthcare data environments, including HIPAA and PHI handling.  

  • Excellent communication skills, with the ability to translate complex technical concepts for both engineering and business audiences.

Preferred Skills:
  • Experience in a healthcare, health IT, or other regulated data environment.

  • Experience operating within HITRUST, NIST, or similar compliance frameworks. 

  • Familiarity with modern warehouse/lakehouse and high-performance analytical data platforms.

  • Experience defining developer tooling, standards, and AI-assisted software development workflows.

Compensation: $150,000 - $200,000Bonus Eligible:

This position is also eligible for a discretionary company bonus, based upon business results.

Benefits:

Employees in this position are eligible to participate in the company sponsored benefit programs, including the following within the first 12 months of employment:

  • Health Insurance (medical, dental, and vision coverage)
  • Paid Time Off (including vacation, sick leave, and flexible holiday days)
  • 401(k) Retirement Plan with employer matching
  • Life and Disability Insurance
  • Employee Assistance Program (EAP)
  • Commuter and/or Transit Benefits (if applicable)

Eligibility for specific benefits may vary based on job classification, schedule (e.g., full-time vs. part-time), work location and length of employment.

Skills Required

  • 7+ years of experience in software architecture, backend engineering, or data engineering, including senior or principal-level technical leadership.
  • Experience architecting complex distributed backend systems using microservices, APIs, and event-driven or streaming patterns.
  • Hands-on experience designing and operating data platforms for high-volume, high-dimensional workloads, including vector databases, graph databases, distributed caching, and semantic retrieval.
  • Experience building AI-native or AI-enabled applications using LLM integration, retrieval-augmented generation, orchestration frameworks, and agentic systems.
  • Strong command of cloud architecture using AWS, Azure, or GCP, with experience operating across cloud and on-premises environments.
  • Ability to remain hands-on in code while providing architecture-level leadership.
  • Working knowledge of healthcare data security, privacy, and compliance requirements, including HIPAA and PHI handling.
  • Excellent communication skills for translating complex technical concepts to engineering and business audiences.
  • Experience in healthcare, health IT, or another regulated data environment.
  • Experience with HITRUST, NIST, or similar compliance frameworks.
  • Familiarity with modern warehouse, lakehouse, and high-performance analytical data platforms.
  • Experience defining developer tooling, standards, and AI-assisted software development workflows.
Am I A Good Fit?
beta
Get Personalized Job Insights.
Our AI-powered fit analysis compares your resume with a job listing so you know if your skills & experience align.

The Company
HQ: New York, NY
2,062 Employees
Year Founded: 1995

What We Do

Our Company: WebMD is a leading provider of health information services to consumers, physicians, healthcare professionals, employers and health plans. Our Business: WebMD is the leading provider of health information and services to consumers and healthcare professionals. The online healthcare information, decision-support applications and communications services that we provide: help consumers take an active role in managing their health by providing objective healthcare information and lifestyle information. make it easier for physicians and healthcare professionals to access clinical reference sources, stay abreast of the latest clinical information, learn about new treatment options, earn continuing medical education credits and communicate with peers. enable employers and health plans to provide their employees and plan members with access to personalized heath and benefit information and decision support technology that helps them make informed benefit, provider and treatment choices.

Similar Jobs

CoreWeave Logo CoreWeave

Senior Special Projects Manager

Cloud • Information Technology • Machine Learning
In-Office
2 Locations
1450 Employees
149K-198K Annually

Tapestry - Coach and Kate Spade Logo Tapestry - Coach and Kate Spade

Temporary Sales Associate

eCommerce • Fashion • Retail • Sales • Wearables • Design
Hybrid
Marlton, NJ, USA
16000 Employees
15-20 Hourly

Samsara Logo Samsara

Sales Operations Manager

Artificial Intelligence • Cloud • Computer Vision • Hardware • Internet of Things • Software
Easy Apply
Remote or Hybrid
United States
4000 Employees
95K-144K Annually

JPMorganChase Logo JPMorganChase

Data Scientist

Financial Services
Hybrid
2 Locations
289097 Employees

Similar Companies Hiring

Sailor Health Thumbnail
Healthtech • Social Impact • Telehealth
New York City, NY
20 Employees
Granted Thumbnail
Artificial Intelligence • Healthtech • Insurance • Mobile • Financial Services
New York, New York
23 Employees
OneImaging Thumbnail
Healthtech
Miami, FL
62 Employees

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account