HistoSonics is a commercial-stage medtech company advancing the Edison® System, a novel non-invasive sonic beam therapy based on histotripsy. Since receiving FDA De Novo grant for the non-invasive destruction of liver tumors in 2023, the company has progressed beyond initial market entry into commercial expansion, reimbursement momentum, and ongoing clinical and pipeline development. In addition to its current liver tumor indication, HistoSonics is pursuing future indications across multiple applications including kidney, pancreas, prostate, neuro, women’s health, and other significant underserved human health areas, to realize the broader potential histotripsy across multiple disease states and medical specialties.
We offer an exciting work culture where cutting-edge science meets real-world application, and each team member’s contribution is important to our success in ensuring our physicians and their patients get what they need most.
Location: Madison, WI - Hybrid
Position Summary (Why this role matters):
NPI Sourcing Manager to serve as the primary supply chain partner for New Product Introduction (NPI) and Research & Development initiatives. In this highly cross-functional role, you will own sourcing strategy and supplier engagement from concept through production release, ensuring component availability, cost competitiveness, and supply continuity for our fastest-moving programs.
Key Responsibilities (What you’ll do):
- Lead supplier sourcing and qualification activities for new components, subassemblies, and finished goods in accordance with ISO 13485 and FDA requirements.
- Partner with Supplier Quality Engineering (SQE) to execute supplier audits, first article inspections (FAIs), and qualification testing.
- Negotiate pricing, lead times, tooling costs, NREs, and supply agreements with prototype and production suppliers; establish favorable commercial terms early in the product lifecycle.
- Partner closely with engineering, program management, quality, and operations to support design reviews, material readiness, and schedule adherence across all active R&D programs.
- Develop should-cost models, track component cost targets, identify supply risks (single-source, long-lead, allocation), and implement dual-source or alternate-part strategies to protect program timelines.
- Manage prototype and sample procurement including purchase order creation, expediting, and delivery tracking to support aggressive R&D build schedules and engineering evaluations.
- Develop and maintain strategic supplier relationships across PCBAs, mechanical, electrical, and custom-fabricated components; conduct business reviews and drive continuous improvement initiatives.
- Own the supply chain handoff from NPI to volume production, including BOM cleanliness, lead time alignment, safety stock strategy, and documentation required for ERP system setup.
Qualifications and Skills:
- Bachelor’s degree in supply chain management, business administration, finance or engineering
- 8+ years in strategic buying or commodity management
- Experience in medical devices.
- Hands-on NPI / product launch experience
- Proficiency in ERP systems (SAP, Oracle, or similar)
- Strong negotiation and contract management skills
- Familiarity with BOM and ECO management
- Ability to manage multiple high-priority programs simultaneously
- Familiarity with DFM / DFX reviews
- Commodity experience in electronics or precision machining
- Experience supporting overseas contract manufacturers
Benefits: We offer a comprehensive benefits package for full-time employees. This includes health, dental, and vision insurance, life, short-term and long-term disability insurance, 401(k), paid time off, and more.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
U.S. Work Authorization & Sponsorship: Employer will not sponsor visas for position.
Skills Required
- Bachelor's degree in supply chain management, business administration, finance, or engineering
- 8+ years of experience in strategic buying or commodity management
- Experience in the medical device industry
- Hands-on new product introduction or product launch experience
- Proficiency with ERP systems such as SAP, Oracle, or similar
- Strong negotiation and contract management skills
- Familiarity with bill of materials and engineering change order management
- Ability to manage multiple high-priority programs simultaneously
- Familiarity with design for manufacturability and design for excellence reviews
- Commodity experience in electronics or precision machining
- Experience supporting overseas contract manufacturers
What We Do
HistoSonics is a growth phase company developing a non-invasive sonic beam therapy platform and procedure using the science of histotripsy. Histotripsy utilizes the pressure created by focused sound energy to liquefy and destroy targeted tissue, including diseased tissue and tumors, at sub-cellular levels. The company’s new platform delivers personalized, tissue specific treatments with precision and control, and without the undesirable side effects of many of today’s interventional and surgical modalities. HistoSonics is led by a team of experienced domain experts and industry leaders with offices in Ann Arbor, MI, Madison, WI, and Minneapolis, MN.
