Manager, R&D Business Operations

Posted Yesterday
Be an Early Applicant
3 Locations
In-Office
Senior level
Healthtech • Biotech • Pharmaceutical • Manufacturing
The Role
Manage purchase orders throughout their lifecycle, translating contract terms into accurate SAP/Ariba setups, tracking budgets, processing amendments, supporting invoice matching and accruals, and ensuring procurement compliance. Partner with R&D, Finance, Strategic Sourcing, Legal, and Accounts Payable; produce operational reports, support audits and close activities, train stakeholders, resolve discrepancies, and improve purchase-to-pay processes.
Summary Generated by Built In
Manager, Business Operations (Purchase Order Management)

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.


As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.


What You Will Do:

  • Create, generate, and manage purchase orders in Ariba/SAP following full contract execution, ensuring alignment with contract terms, budgets, and approved scopes of work in compliance with company policies and service level standard turnaround times.

  • Translate contractual payment terms, milestones, and fee structures into accurate and compliant purchase order structures.

  • Review executed agreements to ensure proper financial setup, including funding allocations, payment schedules, and budget tracking.

  • Process and manage change orders, PO amendments, closures, and funding adjustments in accordance with contract modifications.

  • Partner with R&D, Finance, and Strategic Sourcing to ensure timely PO issuance and resolution of system or budget discrepancies.

  • Monitor purchase order lifecycle activities, including invoice matching, goods receipt confirmations, accrual support, and PO reconciliation.

  • Ensure compliance with internal financial controls, delegation of authority policies, and procurement procedures prior to PO release.

  • Serve as system subject matter expert (SME) for Ariba/SAP purchase order workflows and provide guidance to internal stakeholders.

  • Train business partners on purchase requisition and PO processes, including proper documentation and system requirements.

  • Facilitate weekly or monthly operational status meetings related to PO issuance, budget tracking, and financial metrics as appropriate.

  • Generate reports and dashboards to track PO cycle times, open commitments, spend against budget, and operational KPIs.

  • Support month-end and year-end close activities, including accrual validation and financial reconciliation.

  • Identify and implement process improvements to enhance PO accuracy, system efficiency, and compliance with internal policies and external regulations.

  • Support audit requests and compliance reviews related to procurement and purchase order activities.

Your Profile:

  • Bachelor’s degree required; advanced degree preferred.

  • Minimum 5 years of experience in pharmaceutical/biotech business operations, procurement operations, finance operations, or contract-to-PO management.

  • Demonstrated experience creating and managing purchase orders within enterprise systems (e.g., SAP, Ariba).

  • Strong understanding of procure-to-pay (P2P) processes, including requisitioning, PO generation, invoice matching, and accruals.

  • Experience working cross-functionally with R&D, Finance, Strategic Sourcing, Legal, and Accounts Payable.

  • Strong analytical skills with the ability to interpret contract financial terms and translate them into operational system requirements.

  • Working knowledge of pharmaceutical/biotech regulatory and compliance considerations impacting vendor payments and financial controls.

  • Ability to identify financial discrepancies or operational risks and escalate appropriately.

  • Strong organizational skills with the ability to manage multiple purchase orders, vendors, and deadlines simultaneously.

  • Proficiency in Microsoft Office applications (Word, Excel, PowerPoint), with strong Excel skills for financial tracking and reporting.

  • Experience supporting internal or external audits related to procurement or financial operations.

  • Strong attention to detail and ability to interpret and apply company financial policies, procedures, and internal controls.


Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.


Are you a current ICON Employee? Please click here to apply

Skills Required

  • Bachelor's degree
  • Advanced degree
  • At least 5 years of experience in pharmaceutical or biotech business operations, procurement operations, finance operations, or contract-to-PO management
  • Experience creating and managing purchase orders in enterprise systems such as SAP or Ariba
  • Strong understanding of procure-to-pay processes, including requisitioning, PO generation, invoice matching, and accruals
  • Experience working cross-functionally with R&D, Finance, Strategic Sourcing, Legal, and Accounts Payable
  • Strong analytical skills and ability to interpret contract financial terms
  • Working knowledge of pharmaceutical or biotech regulatory and compliance considerations affecting vendor payments and financial controls
  • Ability to identify financial discrepancies or operational risks and escalate appropriately
  • Strong organizational skills managing multiple purchase orders, vendors, and deadlines
  • Proficiency in Microsoft Office, including strong Excel skills for financial tracking and reporting
  • Experience supporting internal or external procurement or financial operations audits
  • Strong attention to detail and ability to apply financial policies, procedures, and internal controls

ICON plc Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about ICON plc and has not been reviewed or approved by ICON plc.

  • Healthcare Strength Benefits are described as comprehensive, with medical coverage and wellness initiatives highlighted. Larger sites are also associated with added wellness supports such as onsite fitness options and access to an employee assistance program.
  • Leave & Time Off Breadth Time-off and flexibility provisions are positioned as a meaningful part of the total package, including vacation/annual leave and flexible work scheduling. Flexibility is sometimes cited as helping offset long hours in certain roles.
  • Retirement Support Retirement and savings support is presented as a core component of the benefits package, including offerings such as pension arrangements in some locations and a U.S. 401(k) plan with company match. Financial planning resources are also emphasized as part of broader security benefits.

ICON plc Insights

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The Company
HQ: Dublin
34,685 Employees
Year Founded: 1990

What We Do

Since our foundation in Dublin, Ireland in 1990, our mission has been to help our clients to accelerate the development of drugs and devices that save lives and improve quality of life. We do this by delivering best in class information, solutions and performance, with an unyielding focus on quality at all times. We offer a full range of consulting, development and commercialisation services from a global network of offices in 53 countries. We focus our innovation on the factors that are critical to our clients – reducing time to market, reducing cost, and increasing quality – and our global team of experts has extensive experience in a broad range of therapeutic areas.

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