Manager, API Manufacturing Sciences (Hikari Plant) / 課長代理, API技術グループ (光工場)

Posted 4 Hours Ago
Be an Early Applicant
Hiring Remotely in Japan
Remote or Hybrid
Mid level
Healthtech • Software • Analytics • Biotech • Pharmaceutical • Manufacturing
Takeda exists to create better health for people, brighter future for the world.
The Role
Leads API manufacturing science activities, including new product launches, process validation, technology transfers, process improvement, and troubleshooting. Applies data science, statistical and multivariate analysis, mechanistic modeling, and digital tools to optimize processes. Prepares and reviews GMP technical documentation and regulatory submission materials. Requires experience in API or chemical process scale-up, process development, PAT, or related optimization, plus a science or engineering degree and professional English proficiency.
Summary Generated by Built In

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.  I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

タケダの紹介

タケダは「世界中の人々の健康と輝かしい未来に貢献する」ことを企業の存在意義(パーパス)としています。そして目指す未来を共有しながら、一人ひとりが自分の可能性を引き出し、お互いの個性を認め合う、多様性にあふれた先進的な組織作りに取り組んでいます。私たちと一緒に、世界中の人々のいのちに貢献し、さらなる成長と活躍を目指しませんか。

タケダはグローバルな研究開発型のバイオ医薬品のリーディングカンパニーです。従業員は創業時から受け継いできたタケダの価値観であるタケダイズム(誠実=公正・正直・不屈)を道しるべとしながら、患者さんに寄り添い(Patient)人々と信頼関係を築き(Trust)社会的評価を向上させ(Reputation)持続可能な事業を発展させる(Business)を日々の行動指針としています。

募集部門の紹介

API Manufacturing Sciencesは、国内唯一の医薬品原薬(API)を扱う工場において、APIに関する科学的・技術的活動をリードする組織です。製品ライフサイクル全体を俯瞰し、生産体制の立ち上げから継続的な製造プロセス改善、さらには製造委託先への技術移管に至るまで、一貫した技術支援を担っています。本部門では、先端技術やデータサイエンスを取り入れながら、グローバルな製造ネットワークと連携し、継続的なプロセス革新を推進しています。

職務内容

  • 新製品立上げ、プロセスバリデーション、技術移管に関する計画策定および実行
  • API製造プロセスの改善およびトラブルシューティングの実施
  • データサイエンスの実践およびデジタルツールの活用によるプロセスの最適化(統計解析、多変量解析、物理モデル構築等)
  • GMPに基づく各種技術文書の作成および薬事申請関連文書の作成・レビュー

応募要件

実務経験/スキル/知識(以下のいずれか、または複数の経験を有する方)

  • APIもしくは化学品の有機合成およびプロセス化学に基づくスケールアップ経験
  • データサイエンス(統計解析、多変量解析等)または物理モデル(メカニスティックモデル)を活用したプロセス開発・最適化の経験
  • Process Analytical Technology(PAT)を活用したリアルタイムプロセスモニタリングの構築・運用経験
  • 化学プロセスに関する基礎的理解(反応、分離、晶析、乾燥等)
  • デジタルツールに関する知識(Aspen、gPROMS、MODDE、CFD、SIMCA等)
  • 統計解析(回帰分析、DoE、SPC等)または多変量解析に関する基礎知識

学歴/資格/語学

  • 理工系学士以上(化学、化学工学、薬学、製造工学、機械工学、材料工学等)
  • 英語:読み書きおよび会話による業務遂行が可能なレベル

その他

本ポジションでは、ご自身の持つプロセス化学や化学工学などの専門性をベースに、実務レベルでの実験・検討を通じて経験を積みながら成長していきたい方を歓迎します。

自ら手を動かしてコツコツと課題に取り組むことが好きな方、様々な専門性を持つ方とディスカッションしながらチャレンジするのが好きな方に活躍いただける環境です。

Takeda Compensation and Benefits Summary:

  • Allowances: Commutation, Housing, Overtime Work etc.

  • Salary Increase: Annually, Bonus Payment: Twice a year

  • Working Hours: Headquarters (Osaka/ Tokyo) 9:00-17:30, Production Sites (Osaka/ Yamaguchi) 8:00-16:45, (Narita) 8:30-17:15, Research Site (Kanagawa) 9:00-17:45

  • Holidays: Saturdays, Sundays, National Holidays, May Day, Year-End Holidays etc. (approx. 123 days in a year)

  • Paid Leaves: Annual Paid Leave, Special Paid Leave, Sick Leave, Family Support Leave, Maternity Leave, Childcare Leave, Family Nursing Leave.

  • Flexible Work Styles: Flextime, Telework

  • Benefits: Social Insurance, Retirement and Corporate Pension, Employee Stock Ownership Program, etc.

Important Notice concerning working conditions:

  • It is possible the job scope may change at the company’s discretion.

  • It is possible the department and workplace may change at the company’s discretion.

LocationsHikari, Japan

Worker TypeEmployee

Worker Sub-TypeRegular

Time TypeFull time

Skills Required

  • Experience scaling up organic synthesis and process chemistry for APIs or chemicals
  • Experience using data science, statistical or multivariate analysis, or mechanistic models for process development and optimization
  • Experience building or operating real-time process monitoring using Process Analytical Technology
  • Fundamental understanding of chemical processes, including reactions, separation, crystallization, and drying
  • Knowledge of digital tools such as Aspen, gPROMS, MODDE, CFD, or SIMCA
  • Basic knowledge of statistical analysis, regression, Design of Experiments, Statistical Process Control, or multivariate analysis
  • Bachelor's degree or higher in a science or engineering discipline such as chemistry, chemical engineering, pharmacy, manufacturing engineering, mechanical engineering, or materials engineering
  • English proficiency sufficient for professional reading, writing, and conversation

Takeda Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Takeda and has not been reviewed or approved by Takeda.

  • Retirement Support — Employer-funded retirement is described as notably strong, combining a dollar-for-dollar 401(k) match with an additional company contribution that scales with age and service. Access to an employee stock purchase plan further supports long-term wealth building.
  • Parental & Family Support — Paid bonding leave for all parents, substantial adoption/surrogacy reimbursement, and robust caregiver resources (backup care and Maven family-forming support) are emphasized as core strengths. These offerings create a comprehensive safety net for a range of family situations.
  • Healthcare Strength — Multiple medical plan options (nationwide PPO/HSA and regional HMOs), employer HSA funding, and integrated mental-health and well-being programs signal depth in coverage. Preventive care is covered in-network, and plan choices by state expand access.

Takeda Insights

Am I A Good Fit?
beta
Get Personalized Job Insights.
Our AI-powered fit analysis compares your resume with a job listing so you know if your skills & experience align.

The Company
HQ: Cambridge, MA
50,000 Employees
Year Founded: 1781

What We Do

For over 240 years, Takeda’s propensity to evolve has driven the next generation of innovation, and as a future-focused organization, we’re continuing to drive forward with endurance in our steadfast pursuit to achieve the best outcomes for our patients in a rapidly changing world.  We have been preparing for this period of value creation by investing in data, digital and technology, and we’re proud of our employees and their commitment to turning groundbreaking ideas into life-changing impacts.   Since our founding in Japan, integrity and putting patients first have been at the heart of our identity, and we will emerge ready for our future as one of the most trusted and science-driven digital biopharmaceutical companies. Join a team where your innovation impacts lives.   Together, we’ll realize improved outcomes by improving data quality, enhancing launch execution and improving the patient journey. You’ll play a critical role in accelerating data collection and increasing accuracy across all parts of the business. Patients across the globe will benefit from access to treatments afforded by greater opportunities and efficiency in our research and development.  

Why Work With Us

We connect to our history and Japanese heritage through everything we do to bring our purpose, values, vision, and imperatives to life. We are committed to bringing better health and a brighter future to patients. Being a part of Takeda means having the opportunity to be a part of something bigger than yourself.

Gallery

Gallery

Similar Jobs

Takeda Logo Takeda

Operational Excellence Lead, Narita Site

Healthtech • Software • Analytics • Biotech • Pharmaceutical • Manufacturing
Remote or Hybrid
Chiba, JPN
50000 Employees

Takeda Logo Takeda

CCS expert, Sterility Assurance, Hikari Site /光工場 無菌性保証室 CCSエキスパート (汚染管理戦略専門)

Healthtech • Software • Analytics • Biotech • Pharmaceutical • Manufacturing
Remote or Hybrid
Japan
50000 Employees

Takeda Logo Takeda

Scientist

Healthtech • Software • Analytics • Biotech • Pharmaceutical • Manufacturing
Remote or Hybrid
Fujikawa, Minamikoma, Yamanashi, JPN
50000 Employees

Similar Companies Hiring

Onshore Thumbnail
Artificial Intelligence • Fintech • Software • Financial Services
New York, New York
60 Employees
Revel Thumbnail
Aerospace • Hardware • Robotics • Software
Marina Del Rey, California
60 Employees
Blee Thumbnail
Artificial Intelligence • Marketing Tech • Software
New York, New York
30 Employees

Sign up now Access later

Create Free Account

Please log in or sign up to report this job.

Create Free Account