Lead Scientist

Posted 7 Days Ago
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Triangle Trailer Park, Township of Jacksonville, NC, USA
In-Office
Senior level
Biotech
The Role
Lead end-to-end genomic analyses, frame scientific questions, run or directly perform complex analyses (GWAS, PRS), translate results for partners, manage timelines/scope/quality, mentor junior staff, and act as scientific consultant to external partners.
Summary Generated by Built In

Location: Durham, North Carolina (Hybrid)

 

The Mission: Why We Exist

Genomics is a science-led transatlantic TechBio combining large-scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare. We are united by a single vision to help people live longer healthier lives, using the power of genomics.

Genomics aims to help people live longer, healthier lives in two ways: super-charging drug discovery and development for novel treatments with our AI-enabled advanced genetic analytics platform, and by helping people understand their personal risk of common chronic diseases through polygenic risk scores - giving doctors and health systems the chance to get the right people into the right prevention, screening and treatment programmes at the right time.

A Day in the Life

No two projects look the same, but a typical week might see you framing the right scientific question for a complex genomic analysis, then structuring the work so your team can run with it. You make the decisive calls when a problem is ambiguous or novel, and you roll up your sleeves on the toughest analyses yourself rather than watching from the sidelines.

You might act as strategic consultant to an external pharma or biotech partner in the morning - fielding sharp technical questions in real time - and mentor a junior colleague through a tricky method in the afternoon. Throughout, you are translating dense genomic results into clear, actionable insight, spotting delivery risks before they become problems, and keeping one eye on scientific quality and the other on scope, timelines and the partner experience.

Who You Are

You are a scientist who has moved beyond individual contribution and wants genuine ownership of outcomes. You hold a PhD (or equivalent experience) in a quantitative life-science discipline - genomics, bioinformatics, computational biology, statistics or a closely related field - and you have led complex scientific projects from end to end, managing timelines, scope and stakeholder expectations along the way.

You are fluent in genomic data analysis at scale, comfortable with large genetic datasets, GWAS, polygenic risk scores and related methodologies. Success in this role demands a robust grasp of statistical human genetics, applied inventively in a partner-facing environment: you excel at unravelling complex genomic data and have a knack for translating raw findings into actionable consulting insights, working collectively with both your highly skilled internal team and external partners.

You communicate with equal ease whether presenting to a non-specialist audience or debugging a method at your desk, you make sound analytical judgements under uncertainty, and you work naturally across teams. Most of all, you are ready to start bringing others up with you.

 

Your Package

We are committed to providing a transparent, supportive, and rewarding work environment.

 
Compensation & Growth
  • Competitive Salary: Salaries are externally benchmarked annually to ensure top-of-market compensation.

  • Clear Career Path: A straightforward, open progression framework means you'll always know the path to promotion and how to achieve your next career goal.

  • Continuous Learning: Including external courses and a wide library of L&D materials, because your growth is our success.

Wellbeing & Time Off
  • Holiday: 25 days annual leave, plus bank holidays, plus an extra 3-day company-wide shutdown at year-end.

  • Financial & Health Security: Robust benefits including a market-leading pension scheme, comprehensive private health insurance for you and your family with NO excess, critical illness, and life assurance.

  • Enhanced Leave: Enhanced paid family leave to support all new parents.

Work Environment & Culture
  • Flexible Working: Hybrid Working (e.g., From our London, Oxford Office)

  • Truly Inclusive Time Off: Our 'Bank Your Bank Holiday' program allows you to exchange public holidays for dates that hold personal or cultural significance to you.

  • Vibrant Social Culture: From regular Town Halls and team picnics to organised sports events, our social committee ensures frequent opportunities to connect and celebrate.

  • Green Commute: Cycle-to-Work scheme and convenient office locations near major transport hubs.

     

Ready to Build the Future?

If this opportunity excites you, apply now!

We are dedicated to creating a diverse environment and are proud to be an equal-opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

Genomics politely requests no contact from recruitment agencies. We do not accept speculative CVs from recruitment agencies nor accept the fees associated with them.

 

Skills Required

  • PhD or equivalent experience in genomics, bioinformatics, computational biology, statistics, or closely related quantitative life-science discipline
  • Proven experience leading complex scientific projects end-to-end, managing timelines, scope, and stakeholder expectations
  • Fluency in genomic data analysis at scale, including experience with large genetic datasets, GWAS, and polygenic risk scores
  • Robust grasp of statistical human genetics and ability to apply methods creatively in partner-facing settings
  • Strong communication skills for presenting to non-specialists and debugging methods with technical teams
  • Experience mentoring or developing junior colleagues and contributing to team capability growth
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The Company
HQ: Oxford
164 Employees
Year Founded: 2014

What We Do

We are a pioneering healthcare company that aims to transform health through the power of genomics. The company was formed in 2014 by four world-leading statistical and human geneticists at the University of Oxford, including Professor Sir Peter Donnelly and Professor Gil McVean. We use large-scale genetic information to realise preventative medicine and improve drug discovery. We're a world-leader in genomic prevention: a paradigm-changing approach to sustainable healthcare which for the first time allows reliable, personalised estimates of risk for all the common diseases and cancers, well ahead of disease manifestation, allowing accurate and early interventions and tailored screening. Our proprietary algorithms and databases offer something no competitor can: the ability to accurately link minute variation across the entire genome to changes in thousands of biological measurements and disease outcomes, to generate population-level insights for healthcare systems, individual-level insights for clinicians about the risk of common diseases, and new understanding of disease processes. In August 2018, we announced a multi-year collaboration with Vertex to use human genetics and data science to advance discovery of precision medicines. We also have several pilot programmes in development within UK and US healthcare systems. Our team is a multi-disciplinary group focused on finding powerful and creative solutions for bringing subject-leading science to as wide an audience as possible, and, in doing so, offer the chance of transforming lives around the world. The workforce is highly qualified and consists of over 150 people, including genomic scientists, computational biologists, statisticians, software engineers, product developers, data scientists and commercial strategists. We are headquartered in Oxford, with offices in Cambridge (UK), London (UK), and Boston (US).

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