Hardware Engineer, Scientific Instrumentation

Posted 3 Days Ago
Be an Early Applicant
Watertown, MA, USA
In-Office
Mid level
Healthtech • Biotech • Pharmaceutical • Agriculture
The Role
Design and build custom scientific instruments across mechanical, electronics, and firmware domains; develop and execute NGS workflows and assays; maintain sequencing QC; troubleshoot experiments and validate assays with biologists; write protocols/SOPs; set up and maintain lab instrumentation; iterate prototypes to production and communicate technical tradeoffs to team and stakeholders.
Summary Generated by Built In

Who we are

Cultivarium builds scientific tools that turn biological discovery into real-world capability. As a Frontier Research Contractor, we provide technical solutions and hands-on support to partners working on the problems of today. Born a Focused Research Organization, we are drawn to the hardest technological problems in biology and built to tackle them with intensity. We prize builders who efficiently leverage resources to deliver tangible solutions at the frontier, for outsized societal benefit. Our ambition is to study and engineer non-model organisms across the entire tree of life.

What we are looking for

We're expanding our hardware initiatives and now need more leadership of these activities in-house. Cultivarium builds custom equipment to probe more organisms across the tree of life, including an automated imaging incubator, high-throughput electroporation systems, and robotic platforms for engineering biology, much of it built today with outside firms. You’ll design and own these instruments end to end, from prototype to reliable, daily-use tools. You’ll partner closely with wet-lab scientists and a small set of external contractors, and design hardware that doesn’t yet exist to generate new-to-the-world datasets. A successful candidate brings strong engineering judgment to ambiguous problems, a bias for building and iterating, and the range to reason across the mechanical, electrical, and biology boundary.

Responsibilities:

  • Design and own custom instruments for imaging, culturing, and engineering organisms across the tree of life, spanning mechanical systems, electronics and firmware, and the integration between them.

  • Harden prototypes into reliable equipment that runs unattended for long experiments, designing for robustness, manufacturability, and serviceability.

  • Build and extend key subsystems: precision motion and gantry systems, high-voltage electroporation electronics, imaging and illumination, and thermal and environmental control.

  • Integrate instruments with robotic automation and liquid-handling platforms.

  • Scope and manage focused external engineering contractors,.

  • Bring high agency and high standards: take ownership, give and receive candid feedback, and push the team to be its best in service of the science.

Basic Qualifications:

  • You believe that the most interesting biology will be better observed, measured, and engineered with new technologies rather than using those from the past. 

  • Authorized to work without sponsorship.

  • Bachelor's in mechanical engineering, electrical engineering, or a related field, or equivalent professional experience.

  • 3–7+ years designing and shipping real hardware: instruments, devices, or lab equipment. We care more about evidence of compelling outputs and high velocity than years on a résumé. Show us what you've built and how fast you built it.

  • Depth in at least one of mechanical design, electronics, or firmware, with enough range to reason across all three and across the hardware/software boundary.

  • Hands-on experience taking hardware from prototype to working product, including testing, debugging, and iteration.

  • Strong quantitative and analytical skills, reasoning from first principles, with meticulous record-keeping.

  • A strong communicator who explains technical tradeoffs clearly to engineers and non-engineers, with a creative, detail-oriented, collaborative approach.

Advanced Qualifications:

  • Experience building scientific instruments or lab equipment (e.g. bioreactors, culturing systems, optical or fluidic systems).

  • Experience with lab automation, robotics, or instrument control and integration.

  • Proficiency in embedded firmware (C/C++) and/or a modern language for instrument control and data (e.g. Python). Experience with mechanical CAD, PCB design, sensors, or mixed-signal systems.

  • Experience working in a research or early-stage environment where requirements evolve quickly.

  • Track record of technical contributions through shipped products, open-source software, publications, or equivalent demonstrated expertise.

We offer:
  • An opportunity to refine your craft in service of science and society.

  • Paid time off, company holidays, and a year-end closure

  • Medical, dental, and vision insurance

  • 401(k) with employer match

We are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kindt

Skills Required

  • Authorized to work without sponsorship
  • Bachelor's degree in mechanical engineering, electrical engineering, or related field, or equivalent experience
  • 3-7+ years designing and shipping hardware (instruments, devices, or lab equipment)
  • Depth in at least one of mechanical design, electronics, or firmware, with range across all three
  • Hands-on experience taking hardware from prototype to working product, including testing and debugging
  • Strong quantitative and analytical skills with meticulous record-keeping
  • Strong communication skills explaining technical tradeoffs to engineers and non-engineers
  • Experience building scientific instruments or lab equipment (bioreactors, optical/fluidic systems)
  • Experience with lab automation, robotics, or instrument control and integration
  • Proficiency in embedded firmware (C/C++) and/or modern languages for instrument control and data (e.g., Python)
  • Experience with mechanical CAD, PCB design, sensors, or mixed-signal systems
  • Experience in research or early-stage environments where requirements evolve quickly
  • Track record of technical contributions through shipped products, publications, or open-source work
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The Company
25 Employees
Year Founded: 2021

What We Do

Cultivarium is a non-profit bioengineering organization dedicated to unlocking the potential of non-model microorganisms. The company develops open-source genetic tools, resources, and platforms that empower life scientists to study and engineer a diverse range of microbes. By expanding access to novel microorganisms, Cultivarium aims to inspire new research avenues, push the frontiers of biotechnology, and support a more sustainable and inclusive bioeconomy.

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