Externally Sponsored Research (ESR) Manager

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

As a new member of the Revolution Medicines team, the Manager, Externally Sponsored Research (ESR) will play a critical role in the management, tracking, and coordination of our global ESR program. This includes investigator-sponsored trial (IST) proposals and collaborative research. The individual will serve as the central point of contact for submission triage, workflow management, and documentation related to these programs.

The ESR Manager will ensure efficient handling of all proposals by overseeing the receipt, internal review, approval documentation, and tracking processes while maintaining compliance with industry regulations globally and company policies.

Key responsibilities include:

ESR Management

• Oversee the submission workflow for ESR proposals, ensuring proper documentation and review.

• Coordinate ESR committee meetings, facilitating proposal review, tracking outcomes, and documenting approvals.

• Ensure adherence to IST funding guidelines, global compliance policies, and research requirements.

• Maintain ongoing communication with investigators and institutions regarding proposal status, required documentation, and next steps.

Workflow & System Oversight

• Manage the grants management system, ensuring seamless functionality and accessibility for external applicants.

• Track and report key metrics on ESR proposal volume, approval rates, and funding allocations.

• Support the automation and optimization of ESR workflow processes to improve efficiency and compliance.

Cross-Functional Collaboration & Compliance

• Collaborate with Clinical Operations on execution of the ESR program.

• Collaborate with Medical Affairs, Compliance, Legal, and Finance teams to ensure proper due diligence and tracking of funded activities.

• Collaborate with Information Systems on grants management system related topics

• Assist in the preparation of audits, compliance reports, and transparency disclosures (e.g., Sunshine Act reporting as required).

• Provide guidance to external applicants and internal stakeholders on grant submission policies and requirements.

Required Skills, Experience and Education:

• Bachelor’s degree required (Life Sciences, Business, or related field preferred).

• 5+ years of experience in grants administration, medical education, or investigator-sponsored trials within the biotechnology, pharmaceutical, or healthcare industry.

• Experience working with grants management systems, submission portals, and tracking databases.

• Strong knowledge of industry regulations and compliance standards for external funding (PhRMA Code, ACCME, FDA, OIG, Sunshine Act, etc.).

• Proficiency in grants management software and tracking tools to oversee proposal workflow and documentation.

Preferred Skills:

• Experience in oncology or clinical research funding.

• Prior experience in grants or ESR program administration within a biopharma or healthcare organization. 

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