Enterprise Security Lead

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Chicago, IL, USA
Hybrid
140K-200K Annually
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Analytics • Biotech • Generative AI
Tempus is a technology company leading the adoption of AI to advance precision medicine and patient care.
The Role

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

At Tempus, software and AI products are owned and developed by small, autonomous teams composed of engineers, designers, scientists, and product managers. Teams set the goals, build the software, deploy the code, and contribute to a growing software platform that drives research and delivers advanced diagnostic and treatment improvements for our clinical partners and their patients.

Tempus is searching for a driven Security Leader with a strong background in Information Security principles to join our expanding Enterprise Security team. This role combines strategic vision with hands-on expertise. You'll oversee, guide, and design a comprehensive security program safeguarding our IT infrastructure, lab equipment, and sensitive data. While fostering a culture of security awareness and industry standard compliance, you'll leverage your proven expert-level knowledge in a specific domain (e.g., Microsoft Security, Endpoint Security, Network Security) to lead the design, implementation, and maintenance of robust security solutions.

 

Responsibilities:

  • Provide strategic vision and leadership for the Enterprise Security team, defining security priorities and aligning them with overall business objectives.

  • Oversee the design, implementation, and maintenance of comprehensive security solutions across various domains, including Microsoft Security, Endpoint Security, Server Security, Network Security, Asset Management, Device Assurance, Zero Trust Security, PKI, and Compliance.

  • Lead the development and implementation of security policies, procedures, and standards, ensuring they are aligned with industry best practices and regulatory requirements.

  • Guide and mentor Enterprise Security team members, fostering a collaborative environment that promotes continuous learning and professional development.

  • Identify, assess, and mitigate security risks, proactively addressing potential threats and vulnerabilities.

  • Collaborate with IT and other business units to promote security awareness and integrate security best practices into operational processes.

  • Develop and implement a communication strategy to inform stakeholders of security risks, updates, and best practices.

  • Track key security metrics and report on the overall effectiveness of the security program.

Requirements:

  • Proven expert-level knowledge and experience in one or more specific domains, such as Microsoft Security, Endpoint Security, or Network Security.

  • Minimum 7+ years of experience in Information Technology, with a strong understanding of security principles and best practices.

  • Excellent communication, collaboration, and interpersonal skills.

  • Ability to translate technical security concepts into clear and concise language for both technical and non-technical audiences.

  • Strong analytical and problem-solving skills.

  • Experience working in a collaborative environment with IT and other business units.

  • Experience with security frameworks like NIST CSF, CIS Controls, or ISO 27001 (a plus).

  • Experience with security tools and technologies relevant to the scope of the role (a plus).

#LI-SH1

#LI-Hybrid

CHI: $140,000-$200,000

The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. 

What the Team is Saying

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Tempus AI Compensation & Benefits Highlights

  • Healthcare Strength Comprehensive medical, dental, vision, life, and short‑term disability coverage is paired with FSA and EAP/mental‑health support, plus pet insurance. Feedback suggests this broad healthcare foundation is strong for a tech/healthtech employer.
  • Parental & Family Support Parental leave is highlighted across sources, with multi‑week leave for new parents and family supports like an onsite Mother’s Room noted. Feedback suggests these programs are a meaningful part of the package.
  • Wellbeing & Lifestyle Benefits Day‑to‑day perks include a company cafeteria with meals, stocked snacks, an on‑site barista, commuter programs, gym discounts, ERGs, and team outings. Feedback suggests these amenities enhance the on‑site experience.

Tempus AI Insights

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The Company
HQ: Chicago, IL
3,775 Employees
Year Founded: 2015

What We Do

We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time, connect patients with therapies and clinical trials, and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data, Tempus partners with more than half of U.S. oncologists and the majority of the top 20 global pharma companies. Our teams are pioneering work across oncology, neurology, psychiatry, cardiology, and beyond—transforming how care is delivered and therapies are developed. At Tempus, every role contributes to our mission: to help each patient benefit from the experiences of those who came before. For more information, visit tempus.com.

Why Work With Us

We’re looking for people who can change the world. People who question the status quo and refuse to shy away from tough problems. For builders who are never done building, and the learners who are never done learning. Passionate individuals with undying curiosity who want to take on one of the greatest challenges humanity has ever faced—head on.

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Tempus AI Offices

Hybrid Workspace

Employees engage in a combination of remote and on-site work.

Most of the team follows a hybrid policy, with some roles allowing for a fully remote arrangement and some roles being onsite only.

Typical time on-site: 3 days a week
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