We are seeking a visionary and execution-focused Director of Software Engineering to lead our Data Platform engineering organization. In this role, you will drive the technical strategy, architecture, and delivery of our next-generation, cloud-native data platform.
The ideal candidate brings over 15 years of software engineering experience, combining deep technical expertise in big data, cloud infrastructure, and AI-driven workflows (including RAG and LLM applications) with a proven track record of scaling engineering teams (10+ headcount). You will collaborate closely with cross-functional executives to translate complex domain requirements into scalable, secure, and compliant production-grade software.
This role is based in Sunnyvale, California. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site. At our Sunnyvale campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities but candidates must be flexible based on the needs of the business.
Responsibilities
Team Scaling & Culture: Lead, mentor, and scale a multi-disciplinary global engineering organization, fostering a culture of high performance, continuous learning, and technical excellence.
Strategic Roadmap Delivery: Own the technical roadmap and resource allocation, ensuring 95%+ on-time execution of strategic product milestones.
Agile Transformation: Champion and mature Agile/Scrum methodologies to optimize feature velocity, minimize product turnaround time, and maintain high software quality.
Strategic Technical Architecture & Data InnovationCloud-Native Evolution: Architect, govern, and optimize the transition to modern serverless and microservices architectures on AWS, driving structural cost optimization and system elasticity.
Big Data Ecosystems: Define the strategy for next-generation big data platforms utilizing Snowflake, Databricks, Apache Iceberg, AWS Glue, etc. to process, partition, and index petabyte-scale datasets.
Performance Engineering: Oversee analytical and search data model optimizations to continually improve query performance and data pipeline throughput.
AI & Product ModernizationAI-Driven Initiatives: Direct the integration of AI-assisted SDLC tools and architect LLM-enabled product features, including RAG-based semantic search and conversational search workflows.
API & System Interoperability: Oversee the development of high-throughput ETL pipelines and secure, scalable RESTful APIs built on Java / Spring Boot to ensure global data interoperability.
Operational Excellence & ComplianceDevOps & SRE Practices: Mature CI/CD automation pipelines using infrastructure-as-code (Terraform, Ansible, Jenkins) to automate provisioning and security patching.
Security & Compliance: Ensure all platforms strictly adhere to modern cybersecurity standards and regulatory compliance frameworks (e.g., GDPR, HIPAA).
Required Qualifications
15+ years of progressive experience in software engineering, with 5+ years in a dedicated engineering leadership role managing cross-functional, global teams.
Proven ability to interface with executive stakeholders (Product, UX, Architecture) to align engineering outputs with business growth.
Strong experience managing large operational budgets and implementing strategic cloud cost-optimization practices.
Technical Stack & Domain ExpertiseBackend & Architecture: Expert-level knowledge of Java, Spring Boot, Spring MVC, distributed systems design, database sharding, and high-performance microservices.
Data & Analytics: Deep proficiency with Snowflake, Apache Iceberg, AWS Glue, Spark, and Elasticsearch.
AI & Search: Hands-on architecture experience with Retrieval-Augmented Generation (RAG), Large Language Model (LLM) frameworks, and semantic/conversational search.
Cloud & DevOps: Strong expertise in AWS Cloud infrastructure, containerization, and IaC tools (Terraform, Ansible, Jenkins).
Domain Interoperability: Experience in high-volume, regulated data fields (e.g., genomics, healthcare, bioinformatics, or fintech) and data standards (e.g., GA4GH) is highly desirable.
EducationMaster’s Degree in Computer Science, Software Engineering, or a highly related technical field preferred.
Bachelor’s Degree in Computer Science or Engineering or equivalent practical experience.
This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.
GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!
Skills Required
- 15+ years of progressive software engineering experience
- 5+ years in a dedicated engineering leadership role managing cross-functional global teams
- Proven track record scaling engineering teams (10+ headcount)
- Expert-level knowledge of Java, Spring Boot, and Spring MVC
- Deep proficiency with Snowflake, Databricks, Apache Iceberg, AWS Glue, and Spark
- Experience with Elasticsearch and analytical/search data model optimization
- Hands-on architecture experience with RAG, LLM frameworks, and semantic/conversational search
- Extensive AWS Cloud infrastructure experience and containerization expertise
- Experience with IaC and CI/CD tooling such as Terraform, Ansible, and Jenkins
- Experience building high-throughput ETL pipelines and secure RESTful APIs
- Strong experience managing large operational budgets and cloud cost-optimization
- Knowledge of regulatory compliance frameworks relevant to healthcare (HIPAA, GDPR)
- Ability to interface with executive stakeholders and drive strategic roadmaps
- Bachelor's Degree in Computer Science, Engineering, or equivalent practical experience
- Master's Degree in Computer Science, Software Engineering, or related field
- Experience in high-volume regulated data domains (genomics, healthcare, bioinformatics, or fintech) and familiarity with GA4GH standards
- Experience championing Agile/Scrum methodologies
What the Team is Saying
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GRAIL Compensation & Benefits Highlights
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Healthcare Strength — Multiple medical plan options, comprehensive medical/dental/vision coverage, and strong mental health programs are described, with employer HSA contributions up to $3,000 for the HDHP. These elements indicate a well‑rounded health offering.
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Leave & Time Off Breadth — Flexible time off is highlighted, with examples of unlimited/FTO policies working well in practice. Paid holidays and company winter breaks further support time away from work.
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Equity Value & Accessibility — New‑hire equity grants that vest over four years and a discounted Employee Stock Purchase Plan are positioned as meaningful parts of total compensation. Ongoing eligibility for additional equity is also noted.
GRAIL Insights
What We Do
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is using the power of high-intensity sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop and commercialize pioneering products.
Why Work With Us
Everything we do is guided by our mission to detect cancer early, when it can be cured. It’s the reason we’re here, and it’s no small task. The right people make all the difference. That’s why we’re looking for those who strive to share their knowledge, contribute their skills, inspire each other and commit to something bigger than themselves.
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GRAIL Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
GRAIL has a variety of work types depending on the roles. Some roles are onsite like a lab role, some are fully remote like our Galleri Sales Consultant roles. Others are hybrid with 2-3 days onsite. Typically Tuesday and Thursday.
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