The PMO drives business outcomes by transforming strategic vision into execution through robust program governance, modern tools, and proactive change leadership. This function mobilizes high-performing project teams, aligns resource capacity to strategic priorities, and establishes clear accountability for deliverables. As financial and operational stewards, this job family optimizes project investments, proactively mitigates risks, and ensures rigorous adherence to quality standards while leveraging strategic partnerships and holding vendors accountable to ensure project success is achieved and outcomes are realized.
The Director, IT Program Management (Enterprise Infrastructure PMO) leads some of the organization’s most visible, complex, and strategically important technology and business initiatives. This Director operates at the intersection of strategy and execution, connecting work across organizational boundaries, anticipating impacts others may miss, and mobilizing the right teams, leaders, and partners to deliver successful outcomes.
The Director, IT Program Management (Enterprise Infrastructure PMO) is accountable for driving initiative outcomes, ensuring decisions are made, obstacles are removed, and programs remain aligned with strategic objectives. This is a highly visible role for a strategic leader who thrives in ambiguity, builds structure where it does not exist, and acts with urgency and ownership. The ideal candidate is a systems thinker who looks beyond individual projects, proactively identifies dependencies and risks, and drives results through influence rather than direct authority.
Location - Nationwide, fully remote (with preference towards candidates in ET/CT, willing and able to travel to our global HQ in Central Ohio 5-10%)
Responsibilities
- Lead complex, enterprise-critical initiatives with significant organizational impact and executive visibility.
- Take end-to-end ownership of initiative health and outcomes, driving decisions, accountability, and forward momentum.
- Proactively orchestrate work across business and technology organizations, identifying dependencies, risks, and stakeholder needs before they become delivery challenges.
- Establish structure, clarity, and accountability when processes, ownership, or direction are evolving.
- Provide leadership across assigned initiatives, directing and influencing project and program managers responsible for individual workstreams.
- Influence functional leaders, delivery teams, and external partners to drive decisions, remove obstacles, and achieve desired outcomes.
- Bring forward actionable recommendations and solutions rather than simply reporting issues or escalating problems.
- Serve as a trusted advisor to senior leaders, communicating initiative health, risks, decisions, and opportunities with clarity and confidence.
- Strengthen how strategic initiatives are managed and delivered by establishing sustainable practices that improve execution over time.
Qualifications
- Ideally targeting individuals with 10+ years of experience leading complex technology programs, portfolios, or strategic initiatives (including tangible results delivering large-scale transformation, digital, emerging technology, or AI-enabled initiatives).
- Demonstrated ability to identify opportunities, anticipate challenges, and take decisive action in complex and evolving environments.
- Proven success influencing outcomes and establishing accountability across highly matrixed organizations without direct authority.
- Strong business, financial, and operational acumen.
- Significant experience working with senior executives and leading initiatives with substantial organizational visibility.
- Exceptional communication, facilitation, negotiation, and executive presentation skills.
- Experience managing strategic vendor, consulting partner, and contractual relationships.
- Experience leading initiatives with enterprise-wide impact and competing organizational priorities, highly preferred.
- Experience building or evolving operating models, governance structures, or delivery practices - preferred.
- Working knowledge of AI, emerging technologies, and the organizational considerations associated with their implementation.
- Experience with enterprise portfolio management solutions such as Planview, preferred.
- PMP, PgMP, or similar project and program management certifications preferred.
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Anticipated Salary Range $118,200 - $199,980 USD
Bonus Eligible - Yes
Benefits: Cardinal Health offers a wide variety of benefits and programs to support health and well-being.
- Medical, dental and vision coverage
- Paid time off plan
- Health savings account (HSA)
- 401k savings plan
- Access to wages before pay day with myFlexPay
- Flexible spending accounts (FSAs)
- Short- and long-term disability coverage
- Work-Life resources
- Paid parental leave
- Healthy lifestyle programs
Application window anticipated to close: 10/30/2026 * if interested in opportunity, please submit application as soon as possible.
The salary range listed is an estimate. Pay at Cardinal Health is determined by multiple factors including, but not limited to, a candidate’s geographical location, relevant education, experience and skills and an evaluation of internal pay equity.
Cardinal Health supports an inclusive workplace that values diversity of thought, experience and background. We celebrate the power of our differences to create better solutions for our customers by ensuring employees can be their authentic selves each day. Cardinal Health is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, ancestry, age, physical or mental disability, sex, sexual orientation, gender identity/expression, pregnancy, veteran status, marital status, creed, status with regard to public assistance, genetic status or any other status protected by federal, state or local law.
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Skills Required
- 10+ years of experience leading complex technology programs, portfolios, or strategic initiatives
- Experience delivering large-scale transformation, digital, emerging technology, or AI-enabled initiatives
- Ability to identify opportunities, anticipate challenges, and take decisive action in complex environments
- Experience influencing outcomes and establishing accountability across highly matrixed organizations without direct authority
- Strong business, financial, and operational acumen
- Experience working with senior executives and leading highly visible initiatives
- Exceptional communication, facilitation, negotiation, and executive presentation skills
- Experience managing strategic vendors, consulting partners, and contractual relationships
- Experience leading enterprise-wide initiatives with competing organizational priorities
- Experience building or evolving operating models, governance structures, or delivery practices
- Working knowledge of AI, emerging technologies, and organizational considerations associated with implementation
- Experience with enterprise portfolio management solutions such as Planview
- PMP, PgMP, or similar project and program management certification
Cardinal Health Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Cardinal Health and has not been reviewed or approved by Cardinal Health.
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Leave & Time Off Breadth — Paid time off is frequently described as generous, including examples like multiple weeks of vacation, additional sick days, and in some roles even “unlimited” or untracked time off. Parental leave, paid holidays, and volunteer time further broaden the overall leave offering.
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Healthcare Strength — Medical, dental, and vision coverage is positioned as comprehensive, with added supports such as preventive care, telehealth/clinic access, mental health resources, and EAP counseling. Wellness programs and incentives (e.g., premium discounts tied to checkups or healthy lifestyle actions) add to the perceived breadth of healthcare-related support.
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Retirement Support — A 401(k) with company match, along with programs like stock purchase/equity participation and charitable matching, contribute to a stronger total rewards picture beyond base pay. Additional financial supports such as disability coverage and early wage access also enhance the overall package.
Cardinal Health Insights
What We Do
Cardinal Health is a distributor of pharmaceuticals, a global manufacturer and distributor of medical and laboratory products, and a provider of performance and data solutions for healthcare facilities. With 50 years in business, operations in more than 35 countries and approximately 44,000 employees globally, Cardinal Health is essential to care. We are navigating the complexities of healthcare and providing scaled solutions to help our customers thrive in a changing world. We strive to be a trusted healthcare partner by driving growth in evolving areas of healthcare, while building upon our distribution, products, and solutions to meet customer needs.









