Director, Demand/Supply Planning

Posted 3 Days Ago
Be an Early Applicant
South San Francisco, CA, USA
In-Office
203K-264K Annually
Expert/Leader
Biotech
The Role
Leads integrated demand, supply, inventory, and clinical supply planning across an outsourced biotech manufacturing network. Builds forecasts and supply plans, monitors inventory and capacity risks, coordinates CDMO execution, develops scenario analyses, and provides dashboards and recommendations for cross-functional governance. The role improves planning processes and supports clinical development, launch readiness, and patient supply continuity.
Summary Generated by Built In

About Us 

Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.
It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.
 
Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.
 
We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.
 
At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families, we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic—leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn, we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.
 
These values are the foundation of our work, empowering us to make a real difference, every day.
 
 

Reporting to the Senior Director, Head of Planning, the Director, Demand & Supply Planning will lead execution of integrated demand, supply, inventory, and planning processes across Kardigan’s outsourced manufacturing and clinical supply network.

You will work closely with teams across Technical Operations, CMC, Clinical Operations, Quality, Regulatory Affairs, Finance, Procurement, Program Management, External Manufacturing, Clinical Supply Chain, and external partners. This role is a great fit for someone who enjoys bringing structure to ambiguity, connecting strategy to execution, and using data to help teams make smart decisions in a fast-moving clinical development environment.

What You’ll Do

  • Build demand plans that translate clinical enrollment assumptions, protocol requirements, regional plans, and future launch expectations into practical forecasts.
  • Create integrated supply plans across drug substance, drug product, packaging, labeling, testing, release, distribution, and clinical supply activities.
  • Help ensure patients and clinical sites have the supply they need by balancing service, continuity, shelf life, and inventory investment.
  • Track inventory health, supply plan performance, forecast accuracy, capacity constraints, and emerging risks before they become issues.
  • Partner with External Manufacturing and Technical Operations to align CDMO execution activities with approved demand and supply plans.
  • Lead scenario planning for demand changes, manufacturing delays, batch outcomes, inventory needs, capacity availability, and launch readiness.
  • Turn complex planning data into clear recommendations, dashboards, and decision points for cross-functional planning and governance forums.
  • Improve how planning gets done by strengthening templates, assumptions, reporting cadences, data quality, and planning tools.

What You’ll Bring

  • 10–12+ years for Director level in supply chain planning, demand planning, supply planning, clinical supply, manufacturing planning, or related operations roles.
  • Experience in biotechnology, pharmaceutical, medical device, or another regulated life sciences environment.
  • Strong understanding of clinical-stage supply chains, outsourced manufacturing networks, CDMO/CMO coordination, and planning across drug substance, drug product, packaging, labeling, testing, release, and distribution.
  • Ability to build forecasts, supply plans, inventory scenarios, planning dashboards, and data-driven recommendations that support cross-functional decisions.
  • Clear communicator who can influence without direct authority and partner effectively with technical, operational, financial, clinical, and executive stakeholders.
  • Bachelor’s degree in Supply Chain, Operations Management, Engineering, Life Sciences, Business, or a related discipline required; advanced degree, MBA, or APICS/ASCM certification preferred.

Preferred Experience

  • Experience in a clinical-stage, pre-commercial, launch-stage, or rapidly scaling biotech/pharma organization.
  • Experience supporting S&OP, Integrated Business Planning, long-range planning, or supply governance processes.
  • Experience with ERP, planning, inventory visibility, IRT, dashboarding, or analytics tools.
  • Comfort operating in a fast-paced, matrixed environment where priorities evolve and processes are still being built.

Exact Compensation may vary based on skills, experience and location.

Pay range
$203,000$264,000 USD

Skills Required

  • 10–12+ years of experience in supply chain planning, demand planning, supply planning, clinical supply, manufacturing planning, or related operations roles
  • Experience in biotechnology, pharmaceutical, medical device, or another regulated life sciences environment
  • Strong understanding of clinical-stage supply chains and outsourced manufacturing networks
  • Experience coordinating CDMO/CMO activities
  • Experience planning across drug substance, drug product, packaging, labeling, testing, release, and distribution
  • Ability to build forecasts, supply plans, inventory scenarios, planning dashboards, and data-driven recommendations
  • Ability to influence without direct authority and partner with technical, operational, financial, clinical, and executive stakeholders
  • Bachelor’s degree in Supply Chain, Operations Management, Engineering, Life Sciences, Business, or a related discipline
  • Experience in a clinical-stage, pre-commercial, launch-stage, or rapidly scaling biotech or pharmaceutical organization
  • Experience supporting S&OP, Integrated Business Planning, long-range planning, or supply governance processes
  • Experience with ERP, planning, inventory visibility, IRT, dashboarding, or analytics tools
  • Advanced degree or MBA
  • APICS or ASCM certification

Kardigan Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Kardigan and has not been reviewed or approved by Kardigan.

  • Healthcare Strength Comprehensive medical, dental, and vision coverage is paired with life and disability insurance and an EAP, signaling a robust core benefits backbone. Employer materials present this coverage as part of a standard, well-rounded package for a U.S. biotech.
  • Fair & Transparent Compensation Explicit salary ranges are posted for multiple roles and the company highlights competitive salaries, indicating greater pay transparency for candidates. The careers site and job postings also outline an annual bonus program, clarifying elements of total cash compensation.
  • Leave & Time Off Breadth Paid holidays and paid time off are called out, with culture materials referencing “generous” PTO. These signals point to substantive time-off provisions even if accrual details are not yet specified.

Kardigan Insights

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The Company
HQ: Princeton, NJ
56 Employees
Year Founded: 2023

What We Do

Kardigan is a patient-driven heart health company that is modernizing cardiovascular drug development to deliver medicines that move patients beyond symptom management to functional cures. By matching critical disease drivers with treatment responders identified in clinical trials, Kardigan is developing a portfolio of medicines that modify the underlying cardiovascular disease pathophysiology to get patients closer to the cures they deserve. For more information about Kardigan, please visit kardigan.bio. If you are interested in joining our passionate and driven team with deep cardiovascular, biotechnology and operational expertise, please visit kardigan.bio or the careers tab of this page.

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