Cluster HTA Hub Senior Manager

Posted 4 Hours Ago
Be an Early Applicant
2 Locations
In-Office
300K-300K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
Lead HTA technical work across six East European markets: develop economic models, generate evidence (SLRs, NMAs, RWE), prepare HTA dossiers, manage AI-enabled workflows, coordinate submissions, and drive cross-functional and external payer engagements to support reimbursement and value positioning.
Summary Generated by Built In
Use Your Power for Purpose
The Innovating for Growth organization is an agile, efficient, and innovative cluster-led model, designed to unlock growth and accelerate impact for patients. It is centered on uniting colleagues under a single cluster identity, leveraging AI and digital tools, and fostering a culture of continuous improvement. The new structure enables dynamic resource allocation, rapid learning and a start-up spirit that empowers teams to act entrepreneurially. Ultimately, I4G aims to reach more patients, faster, with greater impact and collaboration across countries where empowered teams unlock greater value than ever before.
The HTA is a technical team responsible for supporting the centralized and streamlined HTA process across the cluster, enabled by AI (where to drive efficiencies and reduce complexity in the go-to-market (GTM) model. Operating within the HTA hub established by the HTA Lead, the specialist contributes to new ways of working by generating high-quality health economic evidence, managing AI-supported workflows, and ensuring HTA submissions remain on track. The HTA specialist will have multiple market insights understanding the HTA requirements across countries within the cluster and will enable synergies across markets for HTA submissions.
ROLE SUMMARY
We are looking for a Senior Manager, Health Technology Assessment (HTA) to join the East Europe HTA Hub, covering 6 markets (Poland, Romania, Israel, Bulgaria, Slovakia, Czech Republic).
This role is part of a newly established cluster structure, designed to strengthen HTA capabilities across markets while driving new ways of working and transformation, including AI-enabled approaches.
The position combines EU-level activities (EU JCA, PICOs), HTA dossier development for countries, economic modelling and value development, and cross-functional cluster projects.
ROLE RESPONSIBILITIES
In order of importance, indicate the primary responsibilities critical to the performance of the role. It is recommended not to list actual tasks but focus on 5 essential responsibilities . Please include:
  • Country/ Cluster remit
  • Revenue accountability/ responsibility
  • TA/ Portfolio/ Product responsibility
  • Complexity of the role: Strategic leadership/ Operational/ Implementation management, External Engagement

HTA Development & Technical Execution
  • Design and adapt health economic models (e.g., cost-utility, cost-effectiveness, budget impact) to support HTA submissions across countries within the cluster.
  • Generate and synthesize clinical and economic evidence, including SLRs, NMAs, and real-world data inputs.
  • Prepare value dossiers and submission packages aligned with national and regional HTA requirements.
  • Apply AI-enabled tools for literature review automation, scenario modeling, and data visualization.

Submission Coordination & Quality Assurance
  • Support the end-to-end HTA submission process, ensuring accuracy, consistency, and compliance with internal and external standards.
  • Conduct internal review checkpoints and collaborate with cross-functional teams to address uncertainties and strengthen value propositions.
  • Maintain documentation and version control for all HTA deliverables across markets.

Strategic Collaboration & Knowledge Sharing
  • Work closely with the HTA Lead, Medical and Commercial teams to align technical outputs with strategic objectives.
  • Contribute to internal knowledge sharing by documenting learnings and best practices from HTA projects.
  • Participate in cluster-wide HTA hub activities and support harmonization of processes across cluster.
  • Participate in HTA specialist community of practice across clusters and with GAV community to cross-polinate learnings and best practices.

External Engagement Support
  • Preparing materials for payer interactions, advisory boards, and external consultations.
  • Contribute technical input to policy shaping initiatives led by the HTA Lead or cluster teams.

QUALIFICATIONS
Basic Qualifications
  • Minimum education requirement
  • Area of expertise required
  • Years of experience.

Minimum Requirements:
  • Bachelor's or master's degree in natural sciences and/or public administration
  • Minimum 5 years of experience in HTA, market access, or health economics within pharma, biotech, or consultancy.
  • Strong understanding of HTA frameworks and payer requirements across cluster countries.
  • Hands-on experience in developing health economic models and conducting evidence synthesis
  • Proven track record in preparing HTA dossiers, reimbursement submissions, or value dossiers for agencies
  • Proficiency in modeling software (e.g., Excel, TreeAge, R, Python) and data analysis tools.
  • Experience collaborating with cross-functional teams (clinical, regulatory, market access, medical affairs, pricing).
  • Familiarity with real-world evidence (RWE) generation and use in HTA.
  • Strong analytical skills with a structured approach to problem solving and execution
  • Excellent written communication skills for developing HTA dossiers, value messages, and technical reports.
  • Familiarity with AI-based tools for literature review, data extraction, and scenario simulation.

Preferred Requirements
  • Master's or PhD in Health Economics, Outcomes Research, Public Health, or a related quantitative discipline; PhD is a plus, especially in health economics, outcomes research, or epidemiology.
  • Experience working across countries and abiity to work in matrix organizations

STAKEHOLDER MANAGEMENT
Provide the primary groups or key role(s) that this role will interact with as a regular part of the role responsibilities. Include any external interactions as appropriate.
  • Internal connections: Cluster Commercial Lead, CMO, ICO, other cluster and country marketing and commercial teams, cluster and International commercial excellence and analytics / AI specialists, medical scientific experts, cluster leads and country medical leads, HTA and access leads, finance, business operations, regulatory, safety, legal and other enabling function.
  • External connections: senior HCPs / KOLs, industry associations, patient organizations, government officials, HTA authorities, regulatory authorities.

Pay Transparency Note:
Minimal Annual Gross Base Salary: 300.000 PLN
Annual Bonus: 20%
Company car and other benefits as per Pay Policy.
Please be kindly informed that the above salary conditions apply to Candidates based in Poland only. Applicants from other countries will be a subject to local pay policies.
Purpose
Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.
Digital Transformation Strategy
One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.
Flexibility
We aim to create a trusting, flexible workplace culture which encourages employees to achieve work life harmony, attracts talent and enables everyone to be their best working self. Let's start the conversation!
Equal Employment Opportunity
We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms - allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees.
Disability Inclusion
Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here!
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected]. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Pursuant to Article 24(6) of the Act of June 24, 2024 on the protection of whistleblowers, Pfizer Polska Sp. z o.o. and Pfizer Trading Polska Sp. z o.o. declare that they have adopted a joint internal reporting procedure, which, in accordance with the provisions of the aforementioned Act, is also available to persons applying for employment on the basis of an employment relationship or other legal relationship constituting the basis for providing work or services or performing functions. The content of the procedure is made available upon request sent to the contact person or to the email address [email protected].
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers .
Market Access

Skills Required

  • Bachelor's or master's degree in natural sciences and/or public administration
  • Minimum 5 years of experience in HTA, market access, or health economics within pharma, biotech, or consultancy
  • Strong understanding of HTA frameworks and payer requirements across cluster countries
  • Hands-on experience in developing health economic models and conducting evidence synthesis
  • Proven track record in preparing HTA dossiers, reimbursement submissions, or value dossiers for agencies
  • Proficiency in modeling software (e.g., Excel, TreeAge, R, Python) and data analysis tools
  • Experience collaborating with cross-functional teams (clinical, regulatory, market access, medical affairs, pricing)
  • Familiarity with real-world evidence (RWE) generation and use in HTA
  • Strong analytical skills with a structured approach to problem solving and execution
  • Excellent written communication skills for developing HTA dossiers, value messages, and technical reports
  • Familiarity with AI-based tools for literature review, data extraction, and scenario simulation
  • Master's or PhD in Health Economics, Outcomes Research, Public Health, or related quantitative discipline (PhD is a plus)
  • Experience working across countries and ability to work in matrix organizations

What the Team is Saying

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Pfizer Compensation & Benefits Highlights

  • Healthcare Strength Multiple U.S. medical plan options include telehealth, comprehensive mental‑health support, fertility/family‑building benefits, transgender‑inclusive coverage, and certain Pfizer medications at no cost. A Wellbeing Wallet and wellness resources broaden the health and wellbeing offering.
  • Retirement Support A 401(k) with company matching is paired with an additional Pfizer Retirement Savings Contribution, alongside company‑paid life and disability insurance. One‑on‑one financial planning support is provided through Fidelity.
  • Leave & Time Off Breadth Paid time off spans vacation, holidays, and personal days, with additional caregiver and medical leave. U.S. parental leave commonly includes 12 weeks paid with options for additional unpaid bonding time and a return‑to‑work transition.

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The Company
HQ: New York, NY
121,990 Employees
Year Founded: 1848

What We Do

Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.

Why Work With Us

We are the inventors, the problem solvers, the big thinkers — those who surmount any hurdle to deliver breakthrough medicines to the people who are counting on them the most.

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