ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
Our Real World Solutions Team is looking for an experienced Clinical Trial Manager and Senior Clinical Trial Manager (CTM) that will be responsible for the end-to-end operational oversight of assigned clinical trials, ensuring delivery against agreed timelines, budget, and quality standards. This includes oversight of site management (remote and onsite), clinical team activities, and compliance with regulatory requirements.
The CTM leads Clinical Operations execution and serves as the primary point of accountability for trial delivery, working cross-functionally with internal teams and externally with sponsors.
What you are going to do:
Trial Execution & Oversight
Plan and manage all clinical operations activities across assigned trials.
Ensure delivery in line with scope, timelines, budget, and quality expectations.
Oversee site lifecycle activities, including start-up, activation, monitoring, and close-out.
Team Leadership & Oversight
Lead and oversee project specific operational activities of Clinical Research Associates (CRAs) and Site Management Associates (SMAs).
Provide direction, training, and study performance oversight for clinical team members.
Review monitoring reports, documentation, and study deliverables for quality and compliance.
Site & Monitoring Management
Develop and implement site management and monitoring plans.
Oversee remote and onsite monitoring activities, including visit planning and execution.
Ensure timely collection, review, and maintenance of trial documentation in CTMS.
Risk & Quality Management
Proactively identify risks and implement mitigation strategies.
Utilize metrics and dashboards to monitor study performance and quality.
Support data review and query management activities as needed.
Stakeholder Management
Collaborate with cross-functional teams (Project Management, Data Management, Finance).
Build and maintain strong relationships with sponsors and external partners.
Provide status updates, metrics, and key study insights to stakeholders.
Compliance & Governance
Ensure adherence to ICH-GCP, regulatory requirements, and internal SOPs.
Support audit and inspection readiness.
Additional Contributions
Participate in bid defense activities as required.
Contribute to process improvements and operational best practices.
What do you need:
Bachelor’s degree in life sciences or related field (or equivalent experience) with at least 1+ year of experience in a CTM or equivalent role (CRO or pharmaceutical environment)
Experience managing Phase III and/or IV clinical trials across multiple therapeutic areas.
Knowledge of risk-based monitoring (RBM) principles preferred
Experience managing North American studies
Ability to manage multiple studies and priorities in a fast-paced environment
Strong leadership, organizational, and problem-solving skills
Effective communication and stakeholder management skills
Willingness to travel (~15%)
Key Competencies
Leadership and team management
Strategic planning and execution
Risk assessment and mitigation
Decision-making and problem-solving
Cross-functional collaboration
Communication and stakeholder engagement
#LI-Remote
#LI-AR1
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
- Competitive base salary and performance related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
Skills Required
- Bachelor's degree in life sciences or a related field, or equivalent experience
- At least 1 year of experience in a Clinical Trial Manager or equivalent role in a CRO or pharmaceutical environment
- Experience managing Phase III and/or Phase IV clinical trials across multiple therapeutic areas
- Knowledge of risk-based monitoring principles
- Experience managing North American studies
- Ability to manage multiple studies and priorities in a fast-paced environment
- Strong leadership, organizational, and problem-solving skills
- Effective communication and stakeholder management skills
- Willingness to travel approximately 15%
ICON plc Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about ICON plc and has not been reviewed or approved by ICON plc.
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Healthcare Strength — Benefits are described as comprehensive, with medical coverage and wellness initiatives highlighted. Larger sites are also associated with added wellness supports such as onsite fitness options and access to an employee assistance program.
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Leave & Time Off Breadth — Time-off and flexibility provisions are positioned as a meaningful part of the total package, including vacation/annual leave and flexible work scheduling. Flexibility is sometimes cited as helping offset long hours in certain roles.
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Retirement Support — Retirement and savings support is presented as a core component of the benefits package, including offerings such as pension arrangements in some locations and a U.S. 401(k) plan with company match. Financial planning resources are also emphasized as part of broader security benefits.
ICON plc Insights
What We Do
Since our foundation in Dublin, Ireland in 1990, our mission has been to help our clients to accelerate the development of drugs and devices that save lives and improve quality of life. We do this by delivering best in class information, solutions and performance, with an unyielding focus on quality at all times. We offer a full range of consulting, development and commercialisation services from a global network of offices in 53 countries. We focus our innovation on the factors that are critical to our clients – reducing time to market, reducing cost, and increasing quality – and our global team of experts has extensive experience in a broad range of therapeutic areas.
