B100 Upstream Operations Manager (Dayshift)

Reference no. R2857926 

Position title: B100 Upstream Operations Manager (Dayshift)

Location: Toronto, ON

Duration: Fixed term, 12 months

About the Job

Join a global network that powers how Sanofi delivers — seamlessly, purposefully, and at scale. In Manufacturing & Supply, you’ll help reimagine how life-changing treatments reach people everywhere, faster. 

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

The B100 operations manager is responsible for the relevant manufacturing operations in compliance with cGMP according to their specific production area (upstream, downstream, MWS, etc). The manager is responsible for the daily activities of unionized staff in a cGMP facility in compliance with company policies. This includes responsibility for the scheduling and execution of all operations with adequate level of GMP documentation. This includes support from a user perspective for B100 project activities and adherence to SOPs, cGMP and HSE procedures.

We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.

About Sanofi

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. 

Main Responsibilities:

Technical – 5%

• Supports the design of B100 relevant operations through remaining stages of project

• Review and approve technical and quality related documentation.

• Administration of Miscellaneous equipment (user access, periodic review, audit trail management)

Planning and Execution - 30%

• Development and ownership of production schedules to support validation, engineering runs and full scale manufacturing

• Manages scheduling of preventative maintenance plans, spare parts, BOMs.

• Supports development of manufacturing recipes

• Supports execution of validation activities related to equipment, process and facilities

• Ensures project support and production activities are executed as per defined schedules

• Monitors & communicates team performance with respect to deliverables using visible metrics

• Supports operations execution on the shop floor (MES, PCS)

• Responsible for development and life cycle management of documentation related to manufacturing operations (eBPR, Logs, etc)

• Supports development of operating budget and staffing for operations and project related activities.

• Develop communication approach for operations topics to ensure project milestones are met (escalation, cascading)

cGMP Compliance & Quality - 35%

• Works with QOOQ, QOSA and RA to ensure compliance with GMP requirements, develop quality continuous improvement initiatives, develop staff quality culture and GMP knowledge

• Leads development and maintenance of operating procedures in adherence to global and site policies

• Ensures compliance of facilities & equipment; minimize process deviations and environmental incidences, identify root cause and implement corrective/preventative actions.

• Supports the development of lesson plans, ensure training is completed in a timely manner.

• Ensure lesson plans are updated appropriately and training remains current.

• Conducts inspections for manufacturing operations (GEMBA, MSV)

• Point of contact (lead) for internal/external audits, regulatory inspections, regulatory responses

People and Development - 15%

• Organizes and develops staff to ensure a high performing team; establishes, monitors and

  provides individual feedback on staff objectives; ensures training of staff according to training plans and to continue to develop their competencies; coach staff on personal development goals and document follow up

• Contributes to the B100 management team, communicates and co-operates with other departments to obtain consensus and e sure appropriate service levels

• Hire new employees and follow company’s procedures; responsible for attendance management and time reporting system.

Continuous Improvement - 10%

• Implement and execute lean management systems established for Bulk; ensures continuous improvement of processes; troubleshoot and lead resolution for manufacturing issues

• Identify and lead initiatives to increase process efficiency, quality and/or yield; implements solutions or changes via change control; plans and manages facility and organization improvements

• Provides metrics and other reports as requested

Accountable for a safe workplace - 5%

• Ensures that employees work within the policies, procedures and regulations including

  responding promptly to all health and safety concerns or incidents

• Ensures all critical incidents and accidents are reported to the appropriate authorities; potential safety and health hazards are identified communicated to staff as lessons learned

• Ensures that that personal protective equipment and clothing are available and appropriate for the tasks

• Ensures continuous EHS awareness and improvement by integrating team with site and

  Bulk initiatives

• Cooperation with and assistance to the EHS management and Joint Health and Safety Committee in carrying out their

  functions.

Scope and dimensions:

• Shift size : up to 20 Union staff

• Oversees specific area of operations in Building 100

• Develop and Ensure consistency of communication across shift

About You

Education and Experience:

• Minimum Bachelors in Microbiology/Biochemistry/Chemical Engineering or related Life Science(s).

• Preferred Masters in Microbiology/Biochemistry/Chemical Engineering or related Life Science(s).

• At least 3-5 years of experience in manufacturing within the pharmaceutical/biotech industry (people management experience preferred).

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team. 

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. 

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. 

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs. 

AI Usage 

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

North America Applicants Only

The salary range for this position is:

Final compensation will be determined based on demonstrated experience, skills, location, and other relevant factors. Employees may be eligible to participate in Company employee benefits programs, and additional benefits information can be found through the (CA)LINKOR (US) LINK.

La fourchette salariale pour ce poste est la suivante:

La rémunération finale sera déterminée en fonction de l'expérience démontrée, des compétences, du lieu de travail et d'autres facteurs pertinents. Les employés peuvent être admissibles à participer aux programmes d'avantages sociaux de l'entreprise, et des informations supplémentaires sur les avantages sociaux peuvent être trouvées via le lien