About Us: this is who we are
At Cyprotex US, an Evotec company, we believe that curiosity is the spark that drives innovation and success. As a forward-thinking team, we thrive on challenging the status quo, learning from each other, and pushing the boundaries of what’s possible. We're on a mission to create a place where curiosity isn't just encouraged—it’s celebrated. Are you someone who asks questions, seeks answers, and isn't afraid to go deeper? #BeCureious with us and see where your curiosity can take you!
Cyprotex US specializes in ADME-Tox and Biosciences including both in vitro (laboratory experiments) and in silico (computer modelling) approaches. Cyprotex was founded in 1999. The Company serves the Pharmaceutical and Biotech, Cosmetics/Personal Care and Chemicals Industries as well as academia and not-for-profit organizations. Over 1700 organizations trust Cyprotex for their ADME-Tox and Bioscience research needs.
The Role: Your challenge …in our journey
We’re looking for a passionate and curious Associate Principal Scientist to join our team. If you’re excited by new challenges, solving complex problems, and learning every step of the way, you might just be the perfect fit. In this role, you’ll have the opportunity to drive impactful projects, collaborate with bright minds, and explore uncharted territories.
As an Associate Principal Scientist at Cyprotex, you'll have the freedom to ask the hard questions, think outside the box, and find creative solutions that push us forward. It’s a role where your curiosity will fuel both your personal growth and the success of the team.
What You'll Do:
Perform routine in-vitro ADME assays
Responsible for planning, performing and reporting in vitro metabolism ADME studies for discovery and development stage compounds.
Actively participate in experimental design, perform experiments as well as critically analyze, interpret and report the data to design next steps.
Ability to perform high-impact as well as high throughput studies to completion in a fast paced environment, while managing multiple projects to meet the timelines
Provides scientific knowledge and responsible in establishing new ADME assays as well as contribute to the continuous improvement of the current ADME assays
Guide junior scientists within the department
Assist in data analysis and interpretation
Laboratory support including ordering, equipment calibration and validation Working to a high standard and adhering to our Quality System
Work closely with the Project Managers to ensure the requirements of our clients are met
Assist in running and maintaining robotic systems to support processes.
Perform Quality Review of peer data and assist in consolidating assay control and validation criteria
Work closely with the Project Managers to ensure the requirements of our clients are met
Who You Are:
BS/MS in a scientific relevant field with at least 6 years of related experience in contract research organizations, pharmaceutical industries or academia. Or a PhD in in vitro drug metabolism and 3 years related industry experience.
An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
Experience in drug discovery/development
Broad understanding of ADME, and in particular hands-on experience of executing and interpreting data from in vitro drug metabolism and DDI assays
Knowledge of bioanalytical sciences including LC-MS/MS, GC-MS, biotransformation and physical organic chemistry
Experienced in cell based or biochemical assays.
The base pay range for this position at commencement of employment is expected to be $93,500 to $115,000. This is a salaried exempt position. Base salary offered may vary depending on the individual’s skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, short-term and long-term disability, company paid basic life insurance, 401k company match, flexible work, generous paid time off and paid holiday, wellness and transportation benefits.
Evotec (US) Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.
Skills Required
- PhD in a relevant scientific field with at least 3 years related experience (or equivalent education/experience)
- Experience in High Content Assay development
- Experience with imaging‑based assays
- Experience with MEA (Multi‑Electrode Array) based assays
- Experience in drug discovery/development and broad understanding of toxicology (TOX)
- Experience in cell‑based or biochemical assays
- Ability to perform high‑throughput studies and operate/maintain robotic laboratory systems
- Experience with experimental design, data analysis, interpretation, and reporting
- Excellent oral and written communication skills
- Knowledge and proficiency with Microsoft Word and Outlook
- Strong attention to detail and ability to manage time and work independently
What We Do
Evotec is a biotechnology company that is committed to advancing drug discovery and development. Through flexible business models, we collaborate with pharmaceutical companies, biotechs, foundations, and government agencies on a substantial scale. We believe that by working together, we can make a difference in the lives of patients. Our Pipeline Co-Creation model represents our adaptable, multi-modality, fully integrated end-to-end approach to drive collaborations and services across all phases of drug discovery and development – from discovery of novel targets to achieving Proof of Concept in the clinic and into commercial manufacturing. We aspire to contribute data-driven disease understanding and early disease relevance in humans to bring the probability of success up. We select the right modality, which is then propelled forward on our platforms by our passionate people striving for the fastest and most effective ways towards patient impact. This is enabled by convergence of human ingenuity with data and AI. We also offer specific solutions, products, and CRO/CDMO-like services, always in support of the Biopharma R&D innovator. Our more than 4,000 scientists work closely with numerous partners concurrently, delivering fully integrated research and development portfolios or individual projects with the highest quality standards and efficiency, coupled with great science, passion, engagement, and communication.
