Associate Director, Downstream MS&T

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Position: Associate Director, Downstream MS&T

Manager: Daryl Powers

Location: Primary location: Massachusetts (Devens)

Working with Us
Challenging. Meaningful. Life-changing. Those are not words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You will get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us

Position Summary

The Associate Director of Downstream MS&T will lead a team of approximately 9 Engineers/ Scientists providing direct laboratory support and purification process expertise for biological assets at the Devens site and at global CDMO partners.

This position provides technical leadership with respect to small-scale purification model development, process characterization, process robustness activities, process lifecycle management, investigation support, new technology introduction, new product introduction, tech transfer, regulatory submissions, and filing responses. The successful candidate will have demonstrated subject matter expertise in separation sciences, and will have a track record of successful leadership of technical teams who achieve high-quality results and exhibit a strong culture of excellence.

Reporting to the MS&T Bioprocess Technology director, the successful candidate will lead a dynamic and highly technical team of scientists and engineers by setting appropriate objectives and priorities, overcoming obstacles; and timely delivering results.

Key Responsibilities

• Manage the book of work for the Downstream MS&T team. Effectively prioritize activities and communicate those priorities to the team and key external stakeholders.
• Maintain a culture of inclusive engagement within the team through effective management of technical deliverables and development of the members of the team.
• Support technical investigations and audits at the site and CDMO partners by providing laboratory and technical expertise to ensure successful and robust closure of such investigations and audits.
• Support changes required to maintain or improve downstream operations at the site and CDMO partners.
• Work with global partners in MS&T and Biologics Development to identify and implement purification process improvements and best practices across the manufacturing network.
• Drive the development and implementation of innovative purification and process analytics solutions to provide required experimental data with reduced investment of Downstream MS&T resources.
• Collaborate with Manufacturing Technology, Biologics Development, and site resources to identify solutions to increase process capability and/or plant yield in both the short and long-term. Develop the data and business case to support investment in these solutions; and support the reduction of these solutions to practice through extensive collaboration.
• Partner with Biologics Development to evolve Downstream control strategies and deliver late-stage clinical/next generation programs.
• Responsible for supporting the development of a high performing team and establishing culture of safety and compliance.

Qualifications & Experience

• Science or Engineering Degree in Biotechnology, Biochemical or Chemical Engineering, or related discipline: PhD (~8+yrs of experience), MS (~10+yrs of experience), BS (~15+yrs of experience), with a solid history of technical accomplishments.
• Experience in downstream commercial biologics manufacturing or development.
• Deep technical expertise in downstream biologics bioprocessing and a working understanding of upstream bioprocessing, analytical science, and manufacturing operations.
• Thorough knowledge of model development, process characterization, Quality by Design, validation principles for manufacturing processes, and process control fundamentals in commercial manufacturing.
• Thorough understanding of regulations, and familiarity with regulatory environment and industry trends for Biologics Drug substance.
• Comprehensive experience managing and leading diverse teams, including matrix management.

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. There are other duties and responsibilities that are considered incidental or secondary to the overall purpose of this job. Employees holding this position will be required to perform any other job-related duties as requested by management.

If you come across a role that intrigues you but does not perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™,” every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion, and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture. 

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodation/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. 

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.