AI Application Engineer

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Boston, MA
In-Office
127K-167K Annually
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Software • Database • Analytics
Powering the world’s most important systems with data that saves lives, runs businesses, and shapes the future.
The Role

AI Engineer

We are seeking an AI Engineer to join our Managed Services team. You will design, integrate, and deploy AI solutions—including agentic applications, LLM inference, similarity search, guardrails, and model evaluation— to improve workflows and scalability, and to optimize the deployment, operation, and upgrade of InterSystems cloud solutions.


This role is ideal for a strong software engineer passionate about applying AI to real-world challenges, collaborating with cross-functional teams to build prototypes and deliver production-ready solutions.

Key Responsibilities

  • Design, develop, and deploy AI software components, including agentic applications, LLM inference, foundation model training, and AI-powered development tools.
  • Build AI-driven tools to improve the deployment, operation, and upgrade of InterSystems cloud solutions.
  • Evaluate and integrate agentic AI platforms into coding, testing, CI/CD, and operational workflows.
  • Lead proofs-of-concept, prototypes, and internal tooling to improve cloud-based service delivery.
  • Partner with cross-functional teams to drive AI adoption and best practices.

Required Qualifications

  • 5+ years of experience in software engineering or platform engineering roles.
  • Experience building AI/ML solutions—such as agentic applications, LLM inference, similarity search, vector databases, guardrails, or memory systems.
  • Strong coding skills inPython or other languages such as C++ or ObjectScript.
  • Expertise in cloud environments (e.g., AWS, Google Cloud, Azure, or private cloud) and containerization technologies.

Preferred Qualifications

  • Experience AI-powered development tools (e.g., GitHub Copilot, Tabnine, Replit).
  • Background in DevOps, or Platform Engineering.
  • Hands-on experience with automation tools such as
  • Contributions to open-source AI/ML frameworks or tools are a plus

We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States.

InterSystems is providing a current good faith estimate of the anticipated base salary range for this position depending on a variety of factors including experience, education, skills, and performance.

Other compensation may include a discretionary annual variable target incentive.

The company also provides generous employee benefits including:

  • Medical, vision, and dental insurance
  • Short-term and long-term disability, and life insurance
  • 401(k) Profit Sharing Contribution
  • Paid Time Off and Holidays
  • Parental Leave
  • Tuition reimbursement
The estimated base compensatation range for this role is:
$127,000$167,000 USD

About InterSystems

InterSystems, a creative data technology provider, delivers a unified foundation for next-generation applications for healthcare, finance, manufacturing, and supply chain customers in more than 80 countries. Our data platforms solve interoperability, speed, and scalability problems for large organizations around the globe to unlock the power of data and allow people to perceive data in imaginative ways. Established in 1978, InterSystems is committed to excellence through its 24×7 support for customers and partners around the world. Privately held and headquartered in Boston, Massachusetts, InterSystems has 38 offices in 28 countries worldwide. For more information, please visit InterSystems.com.

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The Company
HQ: Boston, MA
2,407 Employees
Year Founded: 1978

What We Do

InterSystems builds the software that makes complex systems work—reliably, securely, and at scale. For more than 45 years, we’ve been the information engine behind some of the world’s most mission-critical applications in healthcare, government, and business.

Our data management, integration, and analytics technologies help organizations connect disparate systems, turn data into insight, and deliver better outcomes. From enabling interoperable healthcare and advancing clinical care, to powering national infrastructure and large-scale enterprise systems, our technology is used every day by millions of people in more than 80 countries.

What sets InterSystems apart is not just what we build, but how we build it. We focus on long-term innovation, deep engineering excellence, and solving hard problems that truly matter. Our teams work closely with customers to tackle real-world challenges—often behind the scenes, but always at the heart of what keeps essential systems running.

If you’re motivated by meaningful work, technical depth, and the opportunity to have a global impact, you’ll find it here.

Why Work With Us

Because we are a profitable, privately-held software company, we place our clients first in everything we do. You’ll work on meaningful, complex problems alongside deeply curious experts in a culture that values learning, ownership, and long-term growth—without the pressure of quarterly Wall Street demands.

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For the first 3 or 6 months (experience and role dependent), we ask our employees to work in the office 5 days a week. After that time, our employees receive 24 work from home Fridays to use at their discretion throughout the year.

Typical time on-site: None
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