3PL Operations Manager

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Fixed-term contract for one year, with the possibility of extension to a full-time position.

Position Overview
The 3PL Operations Manager is responsible for managing the daily operational activities with Madrigal’s third-party logistics partners (3PLs), ensuring smooth, compliant, and efficient execution of distribution and order-to-cash processes. This role acts as the key operational interface for existing 3PLs and works closely with Quality, Finance, Customer Service, and Supply Chain to resolve day-to-day issues, monitor performance, and drive operational excellence.
This role complements the strategic and implementation responsibilities of the 3PL Distribution Lead by focusing on business-as-usual operations, performance follow-up, and cross-functional coordination both internally and with external logistics partners.

Key Responsibilities

3PL Daily Operations Management

• Oversee daily operational activities with existing 3PL partners to ensure timely and accurate order processing, shipment execution, and inventory handling.
• Serve as the primary point of contact for operational topics and escalations related to current 3PL operations (e.g., product integrity, regulatory / quality compliance, inventory and distribution).
• Monitor inbound and outbound flows, order status, stock movements, and issue resolution to ensure continuity of supply.

Order Fulfillment and Operational Execution

• Coordinate end-to-end operational execution from order receipt through delivery in collaboration with internal and external stakeholders.
• Support order-to-cash activities by ensuring accurate transactional flow, timely invoicing inputs, and effective issue resolution.
• Partner with customer service and commercial teams to address service-related issues and support customer requirements.

Cross-functional Coordination with Quality and Finance

• Work closely with Quality on deviations, temperature excursions, CAPAs, complaints, returns, change controls, and GDP-related operational topics.
• Coordinate with Finance on invoicing accuracy, credit/debit note issues, inventory reconciliation, charge validation, and cost tracking.
• Ensure operational alignment between 3PL activities and internal quality and financial controls.

Performance Monitoring and Continuous Improvement

• Track day-to-day service performance of 3PLs against agreed KPIs such as OTIF, inventory accuracy, order cycle time, and issue resolution.
• Support regular operational review meetings with 3PLs and prepare performance summaries, action logs, and follow-up items.
• Identify process improvement opportunities and drive corrective actions to improve efficiency, compliance, and service quality.

Compliance and Documentation

• Ensure all operational activities are executed in line with GDP requirements, internal procedures, and contractual service expectations.
• Support audits, inspections, and documentation requests by maintaining operational records and ensuring readiness of 3PL-related data.
• Maintain operational SOPs, work instructions, and governance documentation relevant to existing 3PL activities.

Launch and Transition Support

• Provide operational expertise and hands-on support during new market setups, launches, or transitions as needed.
• Support handover of newly implemented 3PLs into steady-state operations once go-live is completed.

Qualifications and Experience

• Bachelor’s degree in Supply Chain, Logistics, Business Administration, or a related field.
• 5-7+ years of experience in logistics, distribution, customer service, or 3PL operations, ideally within the pharmaceutical or healthcare industry.
• Experience working with third-party logistics providers in a regulated environment.
• Advanced understanding of GDP requirements and distribution compliance.
• Experience collaborating cross-functionally with Quality and Finance teams.
• Languages: Fluent in English and Dutch required, Italian and Spanish preferred

Skills and Attributes

• Strong operational mindset with attention to detail and follow-through.
• Ability to manage multiple priorities and resolve day-to-day issues in a structured way.
• Strong communication and stakeholder management skills.
• Analytical and organized, with the ability to monitor KPIs and translate data into action.
• Proactive, hands-on, and solution-oriented approach.

We are committed to fostering an inclusive and diverse workplace and do not discriminate on the basis of any legally protected characteristics. Madrigal processes your personal data in connection with its recruitment and talent sourcing activities in accordance with applicable data protection laws. Further information about how your personal data is processed, together with details of your rights and how to exercise them, is available in our Job Applicant Privacy Notice, which is made available to you if you apply through Workday.

Please note that this job description is not exhaustive and may evolve over time. Only shortlisted candidates will be contacted. Applicants must be authorized to work in the country of employment at the time of application. Employment terms, where applicable, will be governed by relevant collective bargaining agreements.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.