Radical Numerics

HQ
San Francisco
Total Offices: 2
25 Total Employees
The architectures that power modern AI were designed for language, not for science. They were never built to understand DNA, interpret experiments, or learn the rules that govern living systems. Closing this gap represents one of the defining opportunities of our time. Our team has pioneered advances across frontier AI, including the first models trained with one-million-token context windows, and now scaling toward one billion. We focus on innovations on systems and architecture, because building AI for science demands a fundamentally different foundation. As a first application of this technology engine, we are advancing AI for life, the most complex and consequential domain of all. We are the AI team behind Evo and Evo 2, the generative genomics models used to create real gene-editing tools and the first whole genomes designed entirely by AI. That work demonstrated that AI can create biology, not just analyze it. We are now building multimodal models trained directly on the fabric of biology, enabling faster discovery, deeper understanding, and entirely new capabilities. As we push the frontier of general biological intelligence, we will build systems hand-in-hand to ensure global biological resilience: rapid detection, rapid response, and rapid countermeasures against emerging threats, both natural and synthetic. Our mission is ambitious: to reimagine what AI can do for biology, and to build that future. Our advisors include Eric Horvitz, CSO of Microsoft, Chris Ré of Stanford, George Church of Harvard, and Andrew Weber, former Assistant Secretary of Defense for Nuclear, Chemical and Biological Defense Programs.

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Radical Numerics Offices

OnSite Workspace

Employees work from physical offices.

Monday-Thursday, Friday remote optional

Typical time on-site:
HQSan Francisco, California, USA
Tokyo, Tokyo, JPN

Perks + Benefits

Compensation + Total Rewards
Offers company equity
Offers competitive compensation and rewards package

Family + Childcare Benefits
Offers generous parental leave

Healthcare Benefits
Offers dental insurance
Offers health insurance
Offers vision insurance

Retirement Benefits + Financial Planning
Offers 401(K)
Provides 401(K) matching

Time Off
Utilizes an Unlimited PTO policy

Work Environment
Utilizes an open door policy that encourages accessibility
Open office floor plan to encourage communication and collaboration
Hosts in-person all-hands meetings