Jobs at Kyverna Therapeutics

The Sr. Director, Clinical Scientist leads clinical research for Multiple Sclerosis therapies, overseeing study execution, protocol development, and cross-functional collaboration in a biotech setting.

Provide high-trust executive support including complex calendar and travel management, meeting logistics, presentations, communications, project coordination, and confidential administrative processes for senior leadership in a biotech environment.

Lead global regulatory strategy for Kyverna's cell therapy portfolio across development, approval, and commercialization. Drive labeling strategy, health authority engagements (FDA, EMA), regulatory submissions (INDs, BLAs/MAAs), and cross-functional alignment with Clinical, CMC, Commercial, Market Access, and Legal. Mentor and scale the regulatory team, manage external partners, and provide regulatory input for business development and portfolio decisions to enable launch readiness and lifecycle management.

Lead discovery and early development strategy for next-generation immune cell therapies. Oversee multidisciplinary teams, evaluate and advance in vivo CAR-T and cellular engineering technologies, build external collaborations, prioritize discovery investments, and partner with clinical, regulatory, and business teams to progress candidates from discovery through IND-enabling development.

Lead development and execution of CAR T channel strategy and operations, overseeing 3PL, specialty pharmacy, distribution, state licensing, government pricing support, GTN optimization, partner governance, launch readiness, reporting, and cross-functional coordination to ensure scalable, compliant commercialization.

Support QA operations for cell therapy manufacturing: review batch records, support product release and disposition, manage vendor change notifications, oversee deviations/change controls/CAPAs, author and maintain SOPs, support audits and inspection readiness, and drive QMS continuous improvement.

Lead integrated lifecycle strategy for emerging therapeutic platforms from discovery through commercialization. Coordinate cross-functional teams (Research, Clinical, Regulatory, Manufacturing, Quality, Commercial) to drive INDs, pivotal studies, PV/PPQ, launch readiness, and lifecycle expansion. Define development pathways, manufacturing strategies, CDMO partnerships, and commercialization plans to maximize portfolio value and mitigate program risk.

Lead pharmacovigilance operations and safety science for assigned products, overseeing vendor management, case processing quality, signal detection and management, aggregate reporting, risk management plans, regulatory submissions, and inspection readiness in collaboration with cross-functional teams.

Senior leader accountable for integrated development and commercialization strategy of CAR-T programs. Leads lifecycle governance, cross-functional coordination, portfolio prioritization, regulatory and manufacturing readiness, risk assessment, and executive-level decision-making to advance programs from development through regulatory filings and launch.

Lead cross-functional program management for engineered T cell therapy development. Translate strategy into integrated plans, track milestones and risks, drive execution and governance, align stakeholders, and build operational processes. May recruit and supervise junior PM staff.

Lead U.S. commercial sales and go-to-market strategy for CAR-T therapies. Build and scale a specialty sales organization, drive launches and market penetration, manage field teams, collaborate cross-functionally on access and site readiness, and use analytics to monitor KPIs and optimize performance.

The Sr. Director of Marketing Promotions will lead promotional strategies, ensure compliance with regulations, and coordinate with various departments for successful product launches and lifecycle management.

Lead QA operations and strategic quality oversight for CDMOs across plasmid, viral vector, and cell therapy manufacturing. Oversee batch release, batch record review, product disposition, deviations/CAPAs, change controls, and inspection readiness. Drive continuous improvement, monitor quality metrics, and support patient apheresis and lab onboarding to ensure cGMP and regulatory compliance.

Lead Kyverna's external and internal corporate communications with emphasis on pipeline and SPS pre-launch. Develop media, digital/social and website strategies, write press materials and corporate narratives, manage agencies and IR relationships, support crisis communications, and drive employee engagement and internal change communications.

The Senior Clinical Research Scientist will design, execute, and analyze clinical studies, ensuring compliance with GCP and regulatory requirements, and collaborate across multiple departments.

The Sr. Director of Business Development will drive Kyverna's growth strategy through strategic partnerships, licensing, and collaboration in the biopharmaceutical sector.

Lead and build Kyverna's Manufacturing and Supply Chain function for autologous and allogeneic cell therapies. Manage CMOs, vendors, clinical supply, sourcing, logistics, budgets, and regulatory compliance. Develop operational plans, supply orchestration and tracking systems, ensure network readiness for pivotal studies and launches, and recruit and develop a high-performing team.

Lead Process Development for engineered T-cell therapies, overseeing process design, optimization, characterization, technology transfer, GMP support, regulatory CMC documentation, and team leadership. Serve as primary technical interface with CDMOs and cross-functional partners to deliver robust, scalable cell expansion processes and lifecycle change management.