Jobs at Genomics England

Develop and own scalable backend software supporting genomic research, clinical decision-making, and healthcare innovation. Responsibilities include building Python microservices and REST APIs on AWS, working with relational databases and identity platforms such as Okta, developing automated tests, troubleshooting issues, collaborating with engineering and QA teams, and leading feature development. The role also involves technical collaboration with suppliers and mentoring junior engineers.

Embed security into product development by partnering with engineering squads, conducting threat modeling and design reviews, integrating code, dependency, and infrastructure scanning into CI/CD, managing vulnerabilities, and translating security standards into practical guidance. The role also supports the Security Champions program, mentors engineers, and promotes shift-left security across cloud-native applications and delivery pipelines.

Build and maintain Python-based test automation frameworks and suites. Design and execute UI, API, integration and end-to-end tests, create Gherkin test cases, ensure traceability, support CI/CD pipelines, investigate defects, manage test data, and collaborate with product, engineering and QA teams to embed shift-left quality practices across the SDLC.

Design, build and maintain Java-based automated test frameworks and suites (UI, API, integration, regression). Drive shift-left testing, create Gherkin test cases, ensure traceability, execute tests in CI/CD, investigate defects, manage test data, and collaborate with product and engineering teams to improve quality across the SDLC.

Lead end-to-end delivery of technical workstreams across Developer Platform, Test Enablement and SRE. Define and track OKRs, manage risks, dependencies and governance, engage stakeholders, support procurement and budgets, line-manage Delivery colleagues, and promote service-oriented, measurable engineering improvements across the SDLC.

Lead and manage architects across Scalable Tech to provide architectural oversight, governance, and direction for cloud and on-premise platforms. Shape enterprise architecture input, embed best practice, support delivery teams, promote reuse and technical excellence, and drive alignment across engineering, product and delivery stakeholders for large-scale genomics platforms.

Lead enterprise architecture vision, strategy, and roadmaps across clinical, research, data, digital, and corporate capabilities. Define principles, standards, target architectures and transition plans; assess current-state, reduce duplication, and guide major initiatives. Influence senior stakeholders, establish governance, work with security, data, engineering and vendors, and promote reusable patterns to ensure coherent, sustainable technology outcomes.

Lead architecture, design and delivery of enterprise-scale genomic healthcare solutions. Guide squads, influence stakeholders, ensure interoperability (FHIR/GA4GH), cloud/hybrid integration (AWS, HPC, petabyte storage), data governance, metadata management and reusable patterns to support analytics, secure data access and large-scale genomic research services.

Work within multidisciplinary teams to design and run genomic and multi-omics analyses (WGS, GWAS, rare variant testing, fine-mapping, MR). Prepare, QC and harmonise datasets, build and refine pipelines and containers (Nextflow, cloud), benchmark methods, and produce reports and publications. Act as a domain expert supporting internal and external stakeholders on study design, analysis and interpretation in human disease genetics.