Jobs at Exelixis

Leads enterprise digital workplace product strategy, roadmap execution, and delivery across communication, collaboration, content management, productivity, data, and analytics platforms. Partners with business, architecture, engineering, QA, operations, vendors, and stakeholders to define requirements, deliver secure and scalable solutions, improve user experience, monitor performance, and support regulatory compliance including GxP, HIPAA, and GDPR.

Designs and develops Exelixis’s cloud platform, including AWS infrastructure, Terraform-based automation, CI/CD pipelines, DevOps tooling, account provisioning, security controls, and production monitoring. Leads complex technical initiatives, establishes platform strategy, advises stakeholders, resolves advanced infrastructure problems, documents systems, improves operational resilience, and mentors engineers. Requires extensive experience in highly available cloud infrastructure and regulated environments.

Designs and supports AWS cloud platform products, automation tools, CI/CD pipelines, DevOps tooling, infrastructure-as-code solutions, and account provisioning automation. Leads complex technical initiatives, improves development and deployment processes, establishes security and access controls, supports operational excellence, and advises stakeholders on platform strategy. Serves as a technical subject matter expert and mentors engineers while ensuring reliable, compliant, and scalable cloud infrastructure.

Provides complex, confidential administrative support to executives and business-unit leadership. Manages calendars, travel, expenses, correspondence, meetings, conferences, events, filing systems, vendor invoices, and executive communications. Handles sensitive inquiries, prepares reports, supports process improvements, and serves as an information source on company policies and procedures. Requires strong judgment, organization, communication, confidentiality, composure, and advanced Microsoft Office skills.

Performs financial analysis supporting corporate development, business development, M&A, strategic planning, lifecycle management, and corporate finance. Builds valuation, merger consequences, DCF, long-range planning, scenario, sensitivity, and capital structure models. Conducts comparable company analysis, evaluates licensing and acquisition opportunities, supports investment and divestment decisions, maintains WACC calculations, and presents recommendations to executives and the Board. Collaborates cross-functionally and monitors biotech and pharmaceutical market trends.

Supports executive leadership with financial analysis for corporate development, M&A, business development, strategic planning, lifecycle management, and corporate finance. Builds valuation, merger, DCF, long-range planning, scenario, funding, capital structure, and WACC models. Evaluates licensing, acquisition, investment, and divestment opportunities; prepares deal recommendations and Board presentations; analyzes biotech and pharmaceutical peers; and translates complex financial analyses into business recommendations.

Designs and leads cloud platform products, automation, CI/CD pipelines, DevOps tooling, and AWS account provisioning. Owns infrastructure strategy, delivery, security controls, incident response, documentation, observability, and root cause analysis. Serves as a technical subject matter expert, leads complex initiatives, collaborates cross-functionally, and mentors engineers. Requires advanced AWS and Terraform expertise in highly available production environments.

Manages cost, inventory, collaboration, COGS, and CMC R&D accrual accounting. Oversees close activities, reconciliations, standard costs, reserves, variance analysis, reporting, process improvements, audits, SOX compliance, and accounting systems. Partners with supply chain, FP&A, alliance management, and technical accounting teams while providing staff training and supporting accounting projects.

Build foundational AI-enabled applications, prototypes, prompts, tests, documentation, and agentic automations. Translate defined requirements into software components, scripts, integrations, and workflow configurations. Support prompt engineering, retrieval-assisted use cases, API integrations, testing, troubleshooting, documentation, code reviews, and demonstrations. Apply software development lifecycle practices, data privacy, information security, compliance, and responsible AI standards while learning from senior team members.

Leads a portfolio of digital applications supporting pharmaceutical discovery, development, and commercialization. Owns product vision, strategy, roadmaps, requirements, prioritization, lifecycle management, and agile delivery. Partners with business, engineering, architecture, quality, operations, and vendors to deliver secure, compliant, user-centered products. Oversees application stability, regulatory compliance, data and AI practices, quality assurance, KPIs, and continuous improvement while mentoring product team members.

Drafts, negotiates, tracks, and manages contracts supporting research, development, and supply chain functions. The role identifies and communicates contractual risks, troubleshoots agreements, advises internal stakeholders, supports in-house attorneys, and handles miscellaneous legal tasks under supervision. It requires strong contract-management, organization, prioritization, communication, and multitasking skills, with biotechnology, pharmaceutical, or high-tech in-house contracting experience preferred.

Lead complex sourcing and outsourcing initiatives for G&A, IT, and Commercial categories in pharma/biotech. Partner with stakeholders to drive cost savings, contract negotiation, supplier performance, risk mitigation, and process improvements. Mentor junior staff, manage SOWs and vendor governance, and support compliance and audit readiness.

Lead design and implementation of cloud security architectures, investigate and remediate security incidents, integrate security tooling into CI/CD pipelines, assess vulnerabilities, collaborate cross-functionally, and ensure regulatory compliance (SOX, FDA) while improving organizational security posture.

The Associate Principal Architect will design and implement cloud-based data architectures on AWS and Databricks, manage data governance, and lead CI/CD pipelines, optimizing for security and performance in advanced analytics settings.

Lead strategy, architecture, delivery, and operations of enterprise AI platforms and AI-enabled solutions. Define roadmap, build reusable AI capabilities, deliver production-grade generative and agentic AI, establish AI-native engineering practices, ensure responsible AI governance, and partner with cross-functional stakeholders to scale AI adoption and measure business impact.

Build and test AI-enabled prototypes, internal tools, prompts, and agentic automations. Translate requirements into small software components, write basic unit tests, support prompt engineering and API integrations, document designs and runbooks, participate in code reviews and demos, and follow data privacy, security, and responsible AI practices while learning SDLC and team processes.

Design and evolve a cloud analytics platform: define automation, IaC, CI/CD, and governance; lead complex projects; mentor engineers; ensure compliance and platform reliability for regulated biotech environments.

Build and prototype agent-based AI applications and workflows, connecting LLMs, prompts, tools, and APIs. Rapidly prototype then harden code, execute CI/CD and testing, write docs/runbooks, participate in reviews, and apply secure-by-design and responsible AI practices.

Design, build, and deploy production-grade agentic applications and multi-agent workflows that automate IT and business processes. Convert prototypes into hardened services, integrate LLMs and enterprise data sources, implement CI/CD and observability, author runbooks and docs, lead reviews and threat modeling, and apply secure-by-design and responsible AI practices.

The Biostatistics Director leads statistical analysis and clinical trial design, collaborates with teams, manages CROs, and oversees statistical outputs for clinical trials, especially in oncology.