Jobs at BigHat Biosciences

Lead BigHat’s machine learning strategy and a senior ML team developing antibody property models, generative protein models, and agent services. Build production-grade ML and MLOps capabilities, integrate models with automated wet-lab data, deliver computational insights for therapeutic programs, and develop platform offerings for AI and biopharma partners. The role combines technical leadership, hands-on modeling, team mentorship, external engagement, and accountability for reproducible, benchmarked ML impact on antibody design.

Own the full accounting function for a high-growth biotech, including financial close, reporting, technical accounting, R&D accruals, tax, equity accounting, compliance, and audit readiness. Build scalable finance infrastructure, internal controls, and SOX compliance processes while leading a NetSuite implementation and transition from QuickBooks. Prepare board reporting, manage external advisors and auditors, support public-company reporting, implement finance automation, and build an effective accounting team.

Develop generative and predictive machine learning models for antibody sequence, structure, and property design. Build multi-objective protein optimization and LLM-driven methods for lab-in-the-loop drug development, deploy models with engineering teams, and support therapeutic programs. Collaborate across machine learning, drug development, wet-lab science, automation, and data science teams to accelerate the creation of safer, more effective biologic therapies.

Develop generative and predictive machine learning models for therapeutic antibody sequence, structure, and property design. Build multi-objective optimization and agentic LLM methods for lab-in-the-loop protein engineering, deploy models with engineering teams, and support drug development programs. Collaborate with drug developers, wet-lab scientists, automation specialists, and data scientists to translate ML methods into validated antibody candidates.

Develop and scale high-throughput automated assay workflows for antibody and drug discovery. Program laboratory automation instruments and robotic systems, design integrated workcells, troubleshoot bottlenecks, improve reliability and capacity, and collaborate with software engineering and LIMS teams on integrated workflows. Support equipment validation, qualification, documentation, and workflow data analysis while contributing to the growth of the automation team.

Contract SharePoint consultant to design and build program management SharePoint sites, integrate Smartsheet feeds, configure document control workflows and Power Automate automations for IND/regulatory submissions, manage permissions, provide admin support, and hand off to internal teams. Work is remote and US-based with optional Microsoft 365 Copilot/SharePoint AI assessment.